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Journal Abstract Search

465 related items for PubMed ID: 31541870

  • 1. Design and synthesis of (2-(phenylamino)thieno[3,2-d]pyrimidin-4-yl)(3,4,5-trimethoxyphenyl)methanone analogues as potent anti-tubulin polymerization agents.
    Tian C, Chen X, Zhang Z, Wang X, Liu J.
    Eur J Med Chem; 2019 Dec 01; 183():111679. PubMed ID: 31541870
    [Abstract] [Full Text] [Related]

  • 2. Discovery of (2-(pyrrolidin-1-yl)thieno[3,2-d]pyrimidin-4-yl)(3,4,5-trimethoxyphenyl)methanone as a novel potent tubulin depolymerizing and vascular disrupting agent.
    Tian C, Wang M, Shi X, Chen X, Wang X, Zhang Z, Liu J.
    Eur J Med Chem; 2022 Aug 05; 238():114466. PubMed ID: 35635956
    [Abstract] [Full Text] [Related]

  • 3. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
    Eissa IH, Dahab MA, Ibrahim MK, Alsaif NA, Alanazi AZ, Eissa SI, Mehany ABM, Beauchemin AM.
    Bioorg Chem; 2021 Jul 05; 112():104965. PubMed ID: 34020238
    [Abstract] [Full Text] [Related]

  • 4. Novel [1,2,4]triazolo[1,5-a]pyrimidine derivatives as potent antitubulin agents: Design, multicomponent synthesis and antiproliferative activities.
    Yang F, Yu LZ, Diao PC, Jian XE, Zhou MF, Jiang CS, You WW, Ma WF, Zhao PL.
    Bioorg Chem; 2019 Nov 05; 92():103260. PubMed ID: 31525523
    [Abstract] [Full Text] [Related]

  • 5. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
    Romagnoli R, Kimatrai Salvador M, Schiaffino Ortega S, Baraldi PG, Oliva P, Baraldi S, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Balzarini J, Liekens S, Mattiuzzo E, Basso G, Viola G.
    Eur J Med Chem; 2018 Jan 01; 143():683-698. PubMed ID: 29220790
    [Abstract] [Full Text] [Related]

  • 6. Design, synthesis and evaluation of novel bis-substituted aromatic amide dithiocarbamate derivatives as colchicine site tubulin polymerization inhibitors with potent anticancer activities.
    Sun YX, Song J, Kong LJ, Sha BB, Tian XY, Liu XJ, Hu T, Chen P, Zhang SY.
    Eur J Med Chem; 2022 Feb 05; 229():114069. PubMed ID: 34971875
    [Abstract] [Full Text] [Related]

  • 7. Discovery and mechanistic insights into thieno[3,2-d]pyrimidine and heterocyclic fused pyrimidines inhibitors targeting tubulin for cancer therapy.
    Wu C, Zhang L, Zhou Z, Tan L, Wang Z, Guo C, Wang Y.
    Eur J Med Chem; 2024 Oct 05; 276():116649. PubMed ID: 38972078
    [Abstract] [Full Text] [Related]

  • 8. Design, Synthesis, and Biological Evaluation of 1-Methyl-1,4-dihydroindeno[1,2-c]pyrazole Analogues as Potential Anticancer Agents Targeting Tubulin Colchicine Binding Site.
    Liu YN, Wang JJ, Ji YT, Zhao GD, Tang LQ, Zhang CM, Guo XL, Liu ZP.
    J Med Chem; 2016 Jun 09; 59(11):5341-55. PubMed ID: 27172319
    [Abstract] [Full Text] [Related]

  • 9. The Design, Synthesis, and Biological Activities of Pyrrole-Based Carboxamides: The Novel Tubulin Inhibitors Targeting the Colchicine-Binding Site.
    Boichuk S, Galembikova A, Syuzov K, Dunaev P, Bikinieva F, Aukhadieva A, Zykova S, Igidov N, Gankova K, Novikova M, Kopnin P.
    Molecules; 2021 Sep 24; 26(19):. PubMed ID: 34641324
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and biological evaluation of 1-benzyl-N-(2-(phenylamino)pyridin-3-yl)-1H-1,2,3-triazole-4-carboxamides as antimitotic agents.
    Prasad B, Lakshma Nayak V, Srikanth PS, Baig MF, Subba Reddy NV, Babu KS, Kamal A.
    Bioorg Chem; 2019 Mar 24; 83():535-548. PubMed ID: 30472555
    [Abstract] [Full Text] [Related]

  • 11. Design, synthesis, and bioevaluation of pyrazolo[1,5-a]pyrimidine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site with potent anticancer activities.
    Li G, Wang Y, Li L, Ren Y, Deng X, Liu J, Wang W, Luo M, Liu S, Chen J.
    Eur J Med Chem; 2020 Sep 15; 202():112519. PubMed ID: 32650183
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis and biological evaluation of resveratrol-cinnamoyl derivates as tubulin polymerization inhibitors targeting the colchicine binding site.
    Yin Y, Lian BP, Xia YZ, Shao YY, Kong LY.
    Bioorg Chem; 2019 Dec 15; 93():103319. PubMed ID: 31585270
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and evaluation of new 2-chloro-4-aminopyrimidine and 2,6-dimethyl-4-aminopyrimidine derivatives as tubulin polymerization inhibitors.
    Xu S, An B, Li Y, Luo X, Li X, Jia X.
    Bioorg Med Chem Lett; 2018 Jun 01; 28(10):1769-1775. PubMed ID: 29673981
    [Abstract] [Full Text] [Related]

  • 14. Discovery and optimization of 3,4,5-trimethoxyphenyl substituted triazolylthioacetamides as potent tubulin polymerization inhibitors.
    Yang F, He CP, Diao PC, Hong KH, Rao JJ, Zhao PL.
    Bioorg Med Chem Lett; 2019 Jan 01; 29(1):22-27. PubMed ID: 30448234
    [Abstract] [Full Text] [Related]

  • 15. Anti-proliferative potential of triphenyl substituted pyrimidines against MDA-MB-231, HCT-116 and HT-29 cancer cell lines.
    Ranjan Dwivedi A, Kumar V, Kaur H, Kumar N, Prakash Yadav R, Poduri R, Baranwal S, Kumar V.
    Bioorg Med Chem Lett; 2020 Oct 15; 30(20):127468. PubMed ID: 32768647
    [Abstract] [Full Text] [Related]

  • 16. Discovery of 6-aryl-2-(3,4,5-trimethoxyphenyl)thiazole[3,2-b][1,2,4]triazoles as potent tubulin polymerization inhibitors.
    Li N, Guan Q, Hong Y, Zhang B, Li M, Li X, Li B, Wu L, Zhang W.
    Eur J Med Chem; 2023 Aug 05; 256():115402. PubMed ID: 37182330
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis and bioevaluation of 6-aryl-1-(3,4,5-trimethoxyphenyl)-1H-benzo[d]imidazoles as tubulin polymerization inhibitors.
    Liu R, Huang M, Zhang S, Li L, Li M, Sun J, Wu L, Guan Q, Zhang W.
    Eur J Med Chem; 2021 Dec 15; 226():113826. PubMed ID: 34571171
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis and bioevaluation of 2,7-diaryl-pyrazolo[1,5-a]pyrimidines as tubulin polymerization inhibitors.
    Liu R, Zhang S, Huang M, Guo Z, Li L, Li M, Wu L, Guan Q, Zhang W.
    Bioorg Chem; 2021 Oct 15; 115():105220. PubMed ID: 34352709
    [Abstract] [Full Text] [Related]

  • 19. Discovery and biological evaluation of 4,6-pyrimidine analogues with potential anticancer agents as novel colchicine binding site inhibitors.
    Zhang J, Tan L, Wu C, Li Y, Chen H, Liu Y, Wang Y.
    Eur J Med Chem; 2023 Feb 15; 248():115085. PubMed ID: 36621138
    [Abstract] [Full Text] [Related]

  • 20. Design and synthesis of novel 5-(4-chlorophenyl)furan derivatives with inhibitory activity on tubulin polymerization.
    Moussa SA, A Osman EE, Eid NM, Abou-Seri SM, El Moghazy SM.
    Future Med Chem; 2018 Aug 01; 10(16):1907-1924. PubMed ID: 29966433
    [Abstract] [Full Text] [Related]

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