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136 related items for PubMed ID: 31561885
41. The comet assay applied to HepG2 liver spheroids. Elje E, Hesler M, Rundén-Pran E, Mann P, Mariussen E, Wagner S, Dusinska M, Kohl Y. Mutat Res Genet Toxicol Environ Mutagen; 2019 Sep; 845():403033. PubMed ID: 31561895 [Abstract] [Full Text] [Related]
42. Formation of a 3,4-diol-1,2-epoxide metabolite of benz[a]anthracene with cytotoxicity and genotoxicity in a human in vitro hepatocyte culture system. Song MK, Kim YJ, Song M, Choi HS, Park YK, Ryu JC. Environ Toxicol Pharmacol; 2012 Mar; 33(2):212-25. PubMed ID: 22236718 [Abstract] [Full Text] [Related]
43. Baseline and genotoxic compound induced gene expression profiles in HepG2 and HepaRG compared to primary human hepatocytes. Jetten MJ, Kleinjans JC, Claessen SM, Chesné C, van Delft JH. Toxicol In Vitro; 2013 Oct; 27(7):2031-40. PubMed ID: 23911569 [Abstract] [Full Text] [Related]
44. Epigenetic Modifications of the Liver Tumor Cell Line HepG2 Increase Their Drug Metabolic Capacity. Ruoß M, Damm G, Vosough M, Ehret L, Grom-Baumgarten C, Petkov M, Naddalin S, Ladurner R, Seehofer D, Nussler A, Sajadian S. Int J Mol Sci; 2019 Jan 16; 20(2):. PubMed ID: 30654452 [Abstract] [Full Text] [Related]
45. Use of the alkaline comet assay for the detection of transplacental genotoxins in newborn mice. Tripathi DN, Pawar AA, Vikram A, Ramarao P, Jena GB. Mutat Res; 2008 May 31; 653(1-2):134-9. PubMed ID: 18468946 [Abstract] [Full Text] [Related]
46. Investigation of mechanism(s) of DNA damage induced by 4-monochlorobiphenyl (PCB3) metabolites. Xie W, Wang K, Robertson LW, Ludewig G. Environ Int; 2010 Nov 31; 36(8):950-61. PubMed ID: 20129669 [Abstract] [Full Text] [Related]
47. How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop. Kirkland D, Pfuhler S, Tweats D, Aardema M, Corvi R, Darroudi F, Elhajouji A, Glatt H, Hastwell P, Hayashi M, Kasper P, Kirchner S, Lynch A, Marzin D, Maurici D, Meunier JR, Müller L, Nohynek G, Parry J, Parry E, Thybaud V, Tice R, van Benthem J, Vanparys P, White P. Mutat Res; 2007 Mar 30; 628(1):31-55. PubMed ID: 17293159 [Abstract] [Full Text] [Related]
48. The comet assay with multiple mouse organs: comparison of comet assay results and carcinogenicity with 208 chemicals selected from the IARC monographs and U.S. NTP Carcinogenicity Database. Sasaki YF, Sekihashi K, Izumiyama F, Nishidate E, Saga A, Ishida K, Tsuda S. Crit Rev Toxicol; 2000 Nov 30; 30(6):629-799. PubMed ID: 11145306 [Abstract] [Full Text] [Related]
49. The comet assay with MCL-5 cells as an indicator of genotoxic treatment with chemicals and cigarette smoke condensates. Wolz L, Krause G, Scherer G. Altern Lab Anim; 2002 Nov 30; 30(3):331-9. PubMed ID: 12106012 [Abstract] [Full Text] [Related]
50. [Research on the comet assay in vitro by plating HepG2 cells in 96-well plates]. Wang Z, Zhang T, Zhu Y, Zhu J. Wei Sheng Yan Jiu; 2007 Jan 30; 36(1):20-3. PubMed ID: 17424840 [Abstract] [Full Text] [Related]
51. An Adaption of Human-Induced Hepatocytes to In Vitro Genetic Toxicity Tests. Liu W, Xi J, Cao Y, You X, Chen R, Zhang X, Han L, Pan G, Luan Y. Mutagenesis; 2019 May 29; 34(2):165-171. PubMed ID: 30590776 [Abstract] [Full Text] [Related]
52. Random, double- and single-strand DNA breaks can be differentiated in the method of Comet assay by the shape of the comet image. Georgieva M, Zagorchev P, Miloshev G. Electrophoresis; 2015 Oct 29; 36(20):2553-60. PubMed ID: 26178261 [Abstract] [Full Text] [Related]
53. A comparison of whole genome gene expression profiles of HepaRG cells and HepG2 cells to primary human hepatocytes and human liver tissues. Hart SN, Li Y, Nakamoto K, Subileau EA, Steen D, Zhong XB. Drug Metab Dispos; 2010 Jun 29; 38(6):988-94. PubMed ID: 20228232 [Abstract] [Full Text] [Related]
54. Development and validation of alternative metabolic systems for mutagenicity testing in short-term assays. Rueff J, Chiapella C, Chipman JK, Darroudi F, Silva ID, Duverger-van Bogaert M, Fonti E, Glatt HR, Isern P, Laires A, Léonard A, Llagostera M, Mossesso P, Natarajan AT, Palitti F, Rodrigues AS, Schinoppi A, Turchi G, Werle-Schneider G. Mutat Res; 1996 Jun 12; 353(1-2):151-76. PubMed ID: 8692190 [Abstract] [Full Text] [Related]
55. The enzyme-modified comet assay: Past, present and future. Muruzabal D, Collins A, Azqueta A. Food Chem Toxicol; 2021 Jan 12; 147():111865. PubMed ID: 33217526 [Abstract] [Full Text] [Related]
56. Imbalance in the antioxidant defence system and pro-genotoxic status induced by high glucose concentrations: In vitro testing in human liver cells. Acito M, Bartolini D, Ceccarini MR, Russo C, Vannini S, Dominici L, Codini M, Villarini M, Galli F, Beccari T, Moretti M. Toxicol In Vitro; 2020 Dec 12; 69():105001. PubMed ID: 32942007 [Abstract] [Full Text] [Related]
57. Adaptation of the in vitro micronucleus assay for genotoxicity testing using 3D liver models supporting longer-term exposure durations. Conway GE, Shah UK, Llewellyn S, Cervena T, Evans SJ, Al Ali AS, Jenkins GJ, Clift MJD, Doak SH. Mutagenesis; 2020 Sep 12; 35(4):319-330. PubMed ID: 32780103 [Abstract] [Full Text] [Related]
58. In vivo Comet assay on isolated kidney cells to distinguish genotoxic carcinogens from epigenetic carcinogens or cytotoxic compounds. Nesslany F, Zennouche N, Simar-Meintières S, Talahari I, Nkili-Mboui EN, Marzin D. Mutat Res; 2007 Jun 15; 630(1-2):28-41. PubMed ID: 17507283 [Abstract] [Full Text] [Related]
59. DMSO-free highly differentiated HepaRG spheroids for chronic toxicity, liver functions and genotoxicity studies. Rose S, Cuvellier M, Ezan F, Carteret J, Bruyère A, Legagneux V, Nesslany F, Baffet G, Langouët S. Arch Toxicol; 2022 Jan 15; 96(1):243-258. PubMed ID: 34762139 [Abstract] [Full Text] [Related]