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Journal Abstract Search

159 related items for PubMed ID: 31576111

  • 1. Design, Synthesis, And Evaluation Of Cyanopyridines As Anti-Colorectal Cancer Agents Via Inhibiting STAT3 Pathway.
    Xu L, Shi L, Qiu S, Chen S, Lin M, Xiang Y, Zhao C, Zhu J, Shen L, Zuo Z.
    Drug Des Devel Ther; 2019; 13():3369-3381. PubMed ID: 31576111
    [Abstract] [Full Text] [Related]

  • 2. Structure-based discovery of potent and selective small-molecule inhibitors targeting signal transducer and activator of transcription 3 (STAT3).
    Huang Q, Zhong Y, Li B, Ouyang S, Deng L, Mo J, Shi S, Lv N, Wu R, Liu P, Hu W, Zhang X, Wang Y.
    Eur J Med Chem; 2021 Oct 05; 221():113525. PubMed ID: 34000483
    [Abstract] [Full Text] [Related]

  • 3. LL1, a novel and highly selective STAT3 inhibitor, displays anti-colorectal cancer activities in vitro and in vivo.
    Liu Z, Wang H, Guan L, Lai C, Yu W, Lai M.
    Br J Pharmacol; 2020 Jan 05; 177(2):298-313. PubMed ID: 31499589
    [Abstract] [Full Text] [Related]

  • 4. Anlotinib inhibits the progress of colorectal cancer cells by antagonizing VEGFR/JAK2/STAT3 axis.
    Jia ZX, Zhang Z, Li Z, Li A, Xie YN, Wu HJ, Yang ZB, Zhang HM, Zhang XM.
    Eur Rev Med Pharmacol Sci; 2021 Mar 05; 25(5):2331-2343. PubMed ID: 33755971
    [Abstract] [Full Text] [Related]

  • 5. Effect of the isoflavone corylin from cullen corylifolium on colorectal cancer growth, by targeting the STAT3 signaling pathway.
    Yang L, Yao Y, Bai Y, Zheng D, Zhou F, Chen L, Hu W, Xiang Y, Zhao H, Liu Z, Wang L, Huang X, Zhao C.
    Phytomedicine; 2021 Jan 05; 80():153366. PubMed ID: 33080566
    [Abstract] [Full Text] [Related]

  • 6. Novel imidazopyridine suppresses STAT3 activation by targeting SHP-1.
    Su JC, Chang CH, Wu SH, Shiau CW.
    J Enzyme Inhib Med Chem; 2018 Dec 05; 33(1):1248-1255. PubMed ID: 30261753
    [Abstract] [Full Text] [Related]

  • 7. Aminocyanopyridines as anti-lung cancer agents by inhibiting the STAT3 pathway.
    Xu L, Qiu S, Yang L, Xu H, Liu X, Fan S, Cui R, Fu W, Zhao C, Shen L, Wang L, Huang X.
    Mol Carcinog; 2019 Aug 05; 58(8):1512-1525. PubMed ID: 31069881
    [Abstract] [Full Text] [Related]

  • 8. Exploration of novel isoxazole-fused quinone derivatives as anti-colorectal cancer agents through inhibiting STAT3 and elevating ROS level.
    Zhang L, Liu P, Jiang Y, Fan D, He X, Zhang J, Luo B, Sui J, Luo Y, Fu X, Yang T.
    Eur J Med Chem; 2024 Jun 05; 272():116448. PubMed ID: 38704936
    [Abstract] [Full Text] [Related]

  • 9. Apoptosis: A target for anticancer therapy with novel cyanopyridines.
    Ismail MMF, Farrag AM, Harras MF, Ibrahim MH, Mehany ABM.
    Bioorg Chem; 2020 Jan 05; 94():103481. PubMed ID: 31837830
    [Abstract] [Full Text] [Related]

  • 10. Design, synthesis and biological evaluation of novel naphthoquinothiazole derivatives as potent antitumor agents through inhibiting STAT3.
    Fan D, Liu P, Li Z, He X, Zhang L, Jiang W, Ang W, Yang T.
    Bioorg Chem; 2024 Sep 05; 150():107565. PubMed ID: 38905884
    [Abstract] [Full Text] [Related]

  • 11. Bipyridine Derivatives as NOP2/Sun RNA Methyltransferase 3 Inhibitors for the Treatment of Colorectal Cancer.
    Tang Z, Zhang N, Chen S, Fang J, Tang X, Lou Y, Jiang Y, Ma Y, Chen X, Chen Z, Zhan S, Ding X, Ding W, Ma Z.
    J Med Chem; 2024 Aug 08; 67(15):13446-13473. PubMed ID: 39054645
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and biological evaluation of celastrol derivatives as potent antitumor agents with STAT3 inhibition.
    Xu S, Fan R, Wang L, He W, Ge H, Chen H, Xu W, Zhang J, Xu W, Feng Y, Fan Z.
    J Enzyme Inhib Med Chem; 2022 Dec 08; 37(1):236-251. PubMed ID: 34894961
    [Abstract] [Full Text] [Related]

  • 13. Utilization of cyanopyridine in design and synthesis of first-in-class anticancer dual acting PIM-1 kinase/HDAC inhibitors.
    Bass AKA, Nageeb EM, El-Zoghbi MS, Mohamed MFA, Badr M, Abuo-Rahma GEA.
    Bioorg Chem; 2022 Feb 08; 119():105564. PubMed ID: 34959179
    [Abstract] [Full Text] [Related]

  • 14. Design, synthesis and activity of novel 2,6-disubstituted purine derivatives, potential small molecule inhibitors of signal transducer and activator of transcription 3.
    Wang X, He Q, Wu K, Guo T, Du X, Zhang H, Fang L, Zheng N, Zhang Q, Ye F.
    Eur J Med Chem; 2019 Oct 01; 179():218-232. PubMed ID: 31254923
    [Abstract] [Full Text] [Related]

  • 15. Discovery of Novel 3-Cyanopyridines as Survivin Modulators and Apoptosis Inducers.
    Sabour R, Harras MF, Mohamed Al Kamaly O, Altwaijry N.
    Molecules; 2020 Oct 22; 25(21):. PubMed ID: 33105831
    [Abstract] [Full Text] [Related]

  • 16. Palladium (II) Complex Enhances ROS-Dependent Apoptotic Effects via Autophagy Inhibition and Disruption of Multiple Signaling Pathways in Colorectal Cancer Cells.
    Aydinlik S, Erkisa M, Ari F, Celikler S, Ulukaya E.
    Anticancer Agents Med Chem; 2021 Oct 22; 21(10):1284-1291. PubMed ID: 32990544
    [Abstract] [Full Text] [Related]

  • 17. Convallatoxin promotes apoptosis and inhibits proliferation and angiogenesis through crosstalk between JAK2/STAT3 (T705) and mTOR/STAT3 (S727) signaling pathways in colorectal cancer.
    Zhang ZH, Li MY, Wang Z, Zuo HX, Wang JY, Xing Y, Jin C, Xu G, Piao L, Piao H, Ma J, Jin X.
    Phytomedicine; 2020 Mar 22; 68():153172. PubMed ID: 32004989
    [Abstract] [Full Text] [Related]

  • 18. The Natural-Based Antitumor Compound T21 Decreases Survivin Levels through Potent STAT3 Inhibition in Lung Cancer Models.
    Martínez-García D, Pérez-Hernández M, Korrodi-Gregório L, Quesada R, Ramos R, Baixeras N, Pérez-Tomás R, Soto-Cerrato V.
    Biomolecules; 2019 Aug 13; 9(8):. PubMed ID: 31412593
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and biological evaluation of 17-cyanopyridine derivatives of pregnenolone as potential anti-prostate cancer agents.
    Sun Y, Gao P, Zhu L, Li Z, Zhao R, Li C, Shan L.
    Steroids; 2021 Jul 13; 171():108841. PubMed ID: 33901535
    [Abstract] [Full Text] [Related]

  • 20. A Ferrocene Derivative Reduces Cisplatin Resistance in Breast Cancer Cells through Suppression of MDR-1 Expression and Modulation of JAK2/STAT3 Signaling Pathway.
    Noori S, Nourbakhsh M, Farzaneh S, Zarghi A.
    Anticancer Agents Med Chem; 2020 Jul 13; 20(18):2285-2292. PubMed ID: 32767949
    [Abstract] [Full Text] [Related]

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