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Journal Abstract Search

234 related items for PubMed ID: 31585266

  • 1. Discovery of novel oxoindolin derivatives as atypical dual inhibitors for DNA Gyrase and FabH.
    Yang YS, Su MM, Xu JF, Liu QX, Bai LF, Hu XW, Zhu HL.
    Bioorg Chem; 2019 Dec; 93():103309. PubMed ID: 31585266
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis and antibacterial activities of 5-(pyrazin-2-yl)-4H-1,2,4-triazole-3-thiol derivatives containing Schiff base formation as FabH inhibitory.
    Zhang F, Wen Q, Wang SF, Shahla Karim B, Yang YS, Liu JJ, Zhang WM, Zhu HL.
    Bioorg Med Chem Lett; 2014 Jan 01; 24(1):90-5. PubMed ID: 24332628
    [Abstract] [Full Text] [Related]

  • 3. Discovery of novel multi-substituted benzo-indole pyrazole schiff base derivatives with antibacterial activity targeting DNA gyrase.
    Liu H, Chu ZW, Xia DG, Cao HQ, Lv XH.
    Bioorg Chem; 2020 Jun 01; 99():103807. PubMed ID: 32272364
    [Abstract] [Full Text] [Related]

  • 4. Design and synthesis of thiazole derivatives as potent FabH inhibitors with antibacterial activity.
    Li JR, Li DD, Wang RR, Sun J, Dong JJ, Du QR, Fang F, Zhang WM, Zhu HL.
    Eur J Med Chem; 2014 Mar 21; 75():438-47. PubMed ID: 24561667
    [Abstract] [Full Text] [Related]

  • 5. Design, synthesis and molecular docking of 1,4-benzodioxane thiazolidinedione piperazine derivatives as FabH inhibitors.
    Sun J, He W, Liu HY, Qin J, Ye CL.
    Bioorg Chem; 2019 Jul 21; 88():102958. PubMed ID: 31054434
    [Abstract] [Full Text] [Related]

  • 6. Novel 1,2,4-oxadiazole-chalcone/oxime hybrids as potential antibacterial DNA gyrase inhibitors: Design, synthesis, ADMET prediction and molecular docking study.
    Ibrahim TS, Almalki AJ, Moustafa AH, Allam RM, Abuo-Rahma GEA, El Subbagh HI, Mohamed MFA.
    Bioorg Chem; 2021 Jun 21; 111():104885. PubMed ID: 33838559
    [Abstract] [Full Text] [Related]

  • 7. New antibacterial agents: Hybrid bioisoster derivatives as potential E. coli FabH inhibitors.
    Segretti ND, Serafim RA, Segretti MC, Miyata M, Coelho FR, Augusto O, Ferreira EI.
    Bioorg Med Chem Lett; 2016 Aug 15; 26(16):3988-93. PubMed ID: 27426865
    [Abstract] [Full Text] [Related]

  • 8. Design of Arylsulfonylhydrazones as Potential FabH Inhibitors: Synthesis, Antimicrobial Evaluation and Molecular Docking.
    Fernandes TB, Segretti ND, Lourenço FR, Cândido TM, Baby AR, Barbosa EG, Parise-Filho R.
    Med Chem; 2021 Aug 15; 17(5):474-484. PubMed ID: 31763975
    [Abstract] [Full Text] [Related]

  • 9. Discovery of New Schiff Bases Tethered Pyrazole Moiety: Design, Synthesis, Biological Evaluation, and Molecular Docking Study as Dual Targeting DHFR/DNA Gyrase Inhibitors with Immunomodulatory Activity.
    Hassan AS, Askar AA, Naglah AM, Almehizia AA, Ragab A.
    Molecules; 2020 Jun 02; 25(11):. PubMed ID: 32498469
    [Abstract] [Full Text] [Related]

  • 10. Molecular docking, discovery, synthesis, and pharmacological properties of new 6-substituted-2-(3-phenoxyphenyl)-4-phenyl quinoline derivatives; an approach to developing potent DNA gyrase inhibitors/antibacterial agents.
    Alagumuthu M, Arumugam S.
    Bioorg Med Chem; 2017 Feb 15; 25(4):1448-1455. PubMed ID: 28094220
    [Abstract] [Full Text] [Related]

  • 11. Design, synthesis and biological evaluation of metronidazole-thiazole derivatives as antibacterial inhibitors.
    Qin YJ, Wang PF, Makawana JA, Wang ZC, Wang ZN, Yan-Gu, Jiang AQ, Zhu HL.
    Bioorg Med Chem Lett; 2014 Nov 15; 24(22):5279-83. PubMed ID: 25587588
    [Abstract] [Full Text] [Related]

  • 12. Exploration of structure-based on imidazole core as antibacterial agents.
    Duan YT, Wang ZC, Sang YL, Tao XX, Zhu HL.
    Curr Top Med Chem; 2013 Nov 15; 13(24):3118-30. PubMed ID: 24200359
    [Abstract] [Full Text] [Related]

  • 13. Design, synthesis, in vitro antimicrobial evaluation and molecular docking studies of indol-2-one tagged with morpholinosulfonyl moiety as DNA gyrase inhibitors.
    Salem MA, Ragab A, El-Khalafawy A, Makhlouf AH, Askar AA, Ammar YA.
    Bioorg Chem; 2020 Mar 15; 96():103619. PubMed ID: 32036161
    [Abstract] [Full Text] [Related]

  • 14. Design, synthesis, and biological evaluation of chrysin derivatives as potential FabH inhibitors.
    Li HX, Wang ZC, Qian YM, Yan XQ, Lu YD, Zhu HL.
    Chem Biol Drug Des; 2017 Jan 15; 89(1):136-140. PubMed ID: 27860280
    [Abstract] [Full Text] [Related]

  • 15. Computational Approaches to Develop Isoquinoline Based Antibiotics through DNA Gyrase Inhibition Mechanisms Unveiled through Antibacterial Evaluation and Molecular Docking.
    Alagumuthu M, Muralidharan VP, Andrew M, Ahmed MH, Iyer SK, Arumugam S.
    Mol Inform; 2018 Dec 15; 37(12):e1800048. PubMed ID: 30051592
    [Abstract] [Full Text] [Related]

  • 16. Drug efficacy of novel 3-O-methoxy-4-halo disubstituted 5,7-dimethoxy chromans; evaluated via DNA gyrase inhibition, bacterial cell wall lesion and antibacterial prospective.
    Ponnusamy T, Alagumuthu M, Thamaraiselvi S.
    Bioorg Med Chem; 2018 Jul 23; 26(12):3438-3452. PubMed ID: 29803359
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis and antimicrobial activities evaluation of Schiff base derived from secnidazole derivatives as potential FabH inhibitors.
    Li Y, Zhao CP, Ma HP, Zhao MY, Xue YR, Wang XM, Zhu HL.
    Bioorg Med Chem; 2013 Jun 01; 21(11):3120-6. PubMed ID: 23602519
    [Abstract] [Full Text] [Related]

  • 18. Dual inhibition of Staphylococcus aureus DNA gyrase and topoisomerase IV activity by phenylalanine-derived (Z)-5-arylmethylidene rhodanines.
    Werner MM, Patel BA, Talele TT, Ashby CR, Li Z, Zauhar RJ.
    Bioorg Med Chem; 2015 Sep 15; 23(18):6125-37. PubMed ID: 26320664
    [Abstract] [Full Text] [Related]

  • 19. Identification of a new binding site in E. coli FabH using Molecular dynamics simulations: validation by computational alanine mutagenesis and docking studies.
    Ramamoorthy D, Turos E, Guida WC.
    J Chem Inf Model; 2013 May 24; 53(5):1138-56. PubMed ID: 23581389
    [Abstract] [Full Text] [Related]

  • 20. Design of (quinolin-4-ylthio)carboxylic acids as new Escherichia coli DNA gyrase B inhibitors: machine learning studies, molecular docking, synthesis and biological testing.
    Metelytsia L, Hodyna D, Dobrodub I, Semenyuta I, Zavhorodnii M, Blagodatny V, Kovalishyn V, Brazhko O.
    Comput Biol Chem; 2020 Apr 24; 85():107224. PubMed ID: 32018168
    [Abstract] [Full Text] [Related]

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