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Journal Abstract Search

363 related items for PubMed ID: 31586708

  • 1. Design, synthesis and biological evaluation of flexible and rigid analogs of 4H-1,2,4-triazoles bearing 3,4,5-trimethoxyphenyl moiety as new antiproliferative agents.
    Ansari M, Shokrzadeh M, Karima S, Rajaei S, Hashemi SM, Mirzaei H, Fallah M, Emami S.
    Bioorg Chem; 2019 Dec; 93():103300. PubMed ID: 31586708
    [Abstract] [Full Text] [Related]

  • 2. 3-Aryl/Heteroaryl-5-amino-1-(3',4',5'-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization.
    Romagnoli R, Prencipe F, Oliva P, Baraldi S, Baraldi PG, Brancale A, Ferla S, Hamel E, Bortolozzi R, Viola G.
    Bioorg Chem; 2018 Oct; 80():361-374. PubMed ID: 29986184
    [Abstract] [Full Text] [Related]

  • 3. Novel Aldimine-Type Schiff Bases of 4-Amino-5-[(3,4,5-trimethoxyphenyl)methyl]-1,2,4-triazole-3-thione/thiol: Docking Study, Synthesis, Biological Evaluation, and Anti-Tubulin Activity.
    Ameri A, Khodarahmi G, Hassanzadeh F, Forootanfar H, Hakimelahi GH.
    Arch Pharm (Weinheim); 2016 Aug; 349(8):662-81. PubMed ID: 27320785
    [Abstract] [Full Text] [Related]

  • 4. New thiazole-2(3H)-thiones containing 4-(3,4,5-trimethoxyphenyl) moiety as anticancer agents.
    Ansari M, Shokrzadeh M, Karima S, Rajaei S, Fallah M, Ghassemi-Barghi N, Ghasemian M, Emami S.
    Eur J Med Chem; 2020 Jan 01; 185():111784. PubMed ID: 31669850
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and Preclinical Evaluation of Indole Triazole Conjugates as Microtubule Targeting Agents that are Effective against MCF-7 Breast Cancer Cell Lines.
    Yele V, Pindiprolu SKSS, Sana S, Ramamurty DSVNM, Madasi JRK, Vadlamani S.
    Anticancer Agents Med Chem; 2021 Jan 01; 21(8):1047-1055. PubMed ID: 32981511
    [Abstract] [Full Text] [Related]

  • 6. New indole-based chalconoids as tubulin-targeting antiproliferative agents.
    Mirzaei H, Shokrzadeh M, Modanloo M, Ziar A, Riazi GH, Emami S.
    Bioorg Chem; 2017 Dec 01; 75():86-98. PubMed ID: 28922629
    [Abstract] [Full Text] [Related]

  • 7. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
    Eissa IH, Dahab MA, Ibrahim MK, Alsaif NA, Alanazi AZ, Eissa SI, Mehany ABM, Beauchemin AM.
    Bioorg Chem; 2021 Jul 01; 112():104965. PubMed ID: 34020238
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis and biological evaluation of millepachine derivatives as a new class of tubulin polymerization inhibitors.
    Wang G, Peng F, Cao D, Yang Z, Han X, Liu J, Wu W, He L, Ma L, Chen J, Sang Y, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2013 Nov 01; 21(21):6844-54. PubMed ID: 23993668
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis and evaluation of antiproliferative and antitubulin activities of 5-methyl-4-aryl-3-(4-arylpiperazine-1-carbonyl)-4H-1,2,4-triazoles.
    Wang C, Li Y, Liu T, Wang Z, Zhang Y, Bao K, Wu Y, Guan Q, Zuo D, Zhang W.
    Bioorg Chem; 2020 Nov 01; 104():103909. PubMed ID: 33142419
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and biological evaluation of 1-benzyl-N-(2-(phenylamino)pyridin-3-yl)-1H-1,2,3-triazole-4-carboxamides as antimitotic agents.
    Prasad B, Lakshma Nayak V, Srikanth PS, Baig MF, Subba Reddy NV, Babu KS, Kamal A.
    Bioorg Chem; 2019 Mar 01; 83():535-548. PubMed ID: 30472555
    [Abstract] [Full Text] [Related]

  • 11. Design, synthesis and evaluation of novel bis-substituted aromatic amide dithiocarbamate derivatives as colchicine site tubulin polymerization inhibitors with potent anticancer activities.
    Sun YX, Song J, Kong LJ, Sha BB, Tian XY, Liu XJ, Hu T, Chen P, Zhang SY.
    Eur J Med Chem; 2022 Feb 05; 229():114069. PubMed ID: 34971875
    [Abstract] [Full Text] [Related]

  • 12. Novel [1,2,4]triazolo[1,5-a]pyrimidine derivatives as potent antitubulin agents: Design, multicomponent synthesis and antiproliferative activities.
    Yang F, Yu LZ, Diao PC, Jian XE, Zhou MF, Jiang CS, You WW, Ma WF, Zhao PL.
    Bioorg Chem; 2019 Nov 05; 92():103260. PubMed ID: 31525523
    [Abstract] [Full Text] [Related]

  • 13. Molecular diversity of trimethoxyphenyl-1,2,3-triazole hybrids as novel colchicine site tubulin polymerization inhibitors.
    Fu DJ, Li P, Wu BW, Cui XX, Zhao CB, Zhang SY.
    Eur J Med Chem; 2019 Mar 01; 165():309-322. PubMed ID: 30690300
    [Abstract] [Full Text] [Related]

  • 14. Synthesis, biological evaluation, and structure-activity relationships of new tubulin polymerization inhibitors based on 5-amino-1,2,4-triazole scaffold.
    Yang F, Chen L, Lai JM, Jian XE, Lv DX, Yuan LL, Liu YX, Liang FT, Zheng XL, Li XL, Wei LY, You WW, Zhao PL.
    Bioorg Med Chem Lett; 2021 Apr 15; 38():127880. PubMed ID: 33636303
    [Abstract] [Full Text] [Related]

  • 15. Structure-based approaches for the design of 6-aryl-1-(3,4,5-trimethoxyphenyl)-1H-benzo[d][1,2,3]triazoles as tubulin polymerization inhibitors.
    Huang M, Han H, Liu H, Liu R, Li J, Li M, Guan Q, Zhang W, Wang D.
    Eur J Med Chem; 2024 Apr 05; 269():116309. PubMed ID: 38471357
    [Abstract] [Full Text] [Related]

  • 16. Discovery of 6-aryl-2-(3,4,5-trimethoxyphenyl)thiazole[3,2-b][1,2,4]triazoles as potent tubulin polymerization inhibitors.
    Li N, Guan Q, Hong Y, Zhang B, Li M, Li X, Li B, Wu L, Zhang W.
    Eur J Med Chem; 2023 Aug 05; 256():115402. PubMed ID: 37182330
    [Abstract] [Full Text] [Related]

  • 17. Synthesis, biological evaluation, and molecular docking analysis of phenstatin based indole linked chalcones as anticancer agents and tubulin polymerization inhibitors.
    Kode J, Kovvuri J, Nagaraju B, Jadhav S, Barkume M, Sen S, Kasinathan NK, Chaudhari P, Mohanty BS, Gour J, Sigalapalli DK, Ganesh Kumar C, Pradhan T, Banerjee M, Kamal A.
    Bioorg Chem; 2020 Dec 05; 105():104447. PubMed ID: 33207276
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis and bio-evaluation of novel 2-aryl-4-(3,4,5-trimethoxy-benzoyl)-5-substituted-1,2,3-triazoles as the tubulin polymerization inhibitors.
    Huang L, Liu M, Man S, Ma D, Feng D, Sun Z, Guan Q, Zuo D, Wu Y, Zhang W, Bao K.
    Eur J Med Chem; 2020 Jan 15; 186():111846. PubMed ID: 31740055
    [Abstract] [Full Text] [Related]

  • 19. Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation.
    Hagras M, El Deeb MA, Elzahabi HSA, Elkaeed EB, Mehany ABM, Eissa IH.
    J Enzyme Inhib Med Chem; 2021 Dec 15; 36(1):640-658. PubMed ID: 33588683
    [Abstract] [Full Text] [Related]

  • 20. Design, Synthesis and Cytotoxic Evaluation of Novel Chalcone Derivatives Bearing Triazolo[4,3-a]-quinoxaline Moieties as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects.
    Alswah M, Bayoumi AH, Elgamal K, Elmorsy A, Ihmaid S, Ahmed HEA.
    Molecules; 2017 Dec 27; 23(1):. PubMed ID: 29280968
    [Abstract] [Full Text] [Related]

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