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Journal Abstract Search

177 related items for PubMed ID: 31610375

  • 1. Discovery of 3-(((9H-purin-6-yl)amino)methyl)-4,6-dimethylpyridin-2(1H)-one derivatives as novel tubulin polymerization inhibitors for treatment of cancer.
    Zhang Q, Hu X, Wan G, Wang J, Li L, Wu X, Liu Z, Yu L.
    Eur J Med Chem; 2019 Dec 15; 184():111728. PubMed ID: 31610375
    [Abstract] [Full Text] [Related]

  • 2. Discovery of 9H-purins as potential tubulin polymerization inhibitors: Synthesis, biological evaluation and structure-activity relationships.
    Zhou ZZ, Shi XD, Feng HF, Cheng YF, Wang HT, Xu JP.
    Eur J Med Chem; 2017 Sep 29; 138():1126-1134. PubMed ID: 28763647
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis and biological evaluation of a novel tubulin inhibitor SKLB0565 targeting the colchicine binding site.
    Hu X, Li L, Zhang Q, Wang Q, Feng Z, Xu Y, Xia Y, Yu L.
    Bioorg Chem; 2020 Apr 29; 97():103695. PubMed ID: 32120073
    [Abstract] [Full Text] [Related]

  • 4. Design, synthesis, and biological evaluation of novel benzodiazepine derivatives as anticancer agents through inhibition of tubulin polymerization in vitro and in vivo.
    Pang Y, Lin H, Ou C, Cao Y, An B, Yan J, Li X.
    Eur J Med Chem; 2019 Nov 15; 182():111670. PubMed ID: 31499359
    [Abstract] [Full Text] [Related]

  • 5. Discovery of novel 2-substituted 2, 3-dihydroquinazolin-4(1H)-one derivatives as tubulin polymerization inhibitors for anticancer therapy: The in vitro and in vivo biological evaluation.
    Shi C, Yang B, He Z, Yang J, Li L, Song J, Xu S, Song W, Yang J.
    Eur J Med Chem; 2024 Nov 05; 277():116766. PubMed ID: 39163776
    [Abstract] [Full Text] [Related]

  • 6. The discovery of novel indazole derivatives as tubulin colchicine site binding agents that displayed potent antitumor activity both in vitro and in vivo.
    Cui YJ, Ma CC, Zhang CM, Tang LQ, Liu ZP.
    Eur J Med Chem; 2020 Feb 01; 187():111968. PubMed ID: 31865012
    [Abstract] [Full Text] [Related]

  • 7. Discovery of novel tubulin/HDAC dual-targeting inhibitors with strong antitumor and antiangiogenic potency.
    Wang Y, Sun M, Wang Y, Qin J, Zhang Y, Pang Y, Yao Y, Yang H, Duan Y.
    Eur J Med Chem; 2021 Dec 05; 225():113790. PubMed ID: 34454126
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
    Wang G, Li C, He L, Lei K, Wang F, Pu Y, Yang Z, Cao D, Ma L, Chen J, Sang Y, Liang X, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2014 Apr 01; 22(7):2060-79. PubMed ID: 24629450
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis, and biological evaluation of 1-substituted -2-aryl imidazoles targeting tubulin polymerization as potential anticancer agents.
    Li L, Quan D, Chen J, Ding J, Zhao J, Lv L, Chen J.
    Eur J Med Chem; 2019 Dec 15; 184():111732. PubMed ID: 31610372
    [Abstract] [Full Text] [Related]

  • 10. Discovery of novel vinyl sulfone derivatives as anti-tumor agents with microtubule polymerization inhibitory and vascular disrupting activities.
    Li W, Yin Y, Yao H, Shuai W, Sun H, Xu S, Liu J, Yao H, Zhu Z, Xu J.
    Eur J Med Chem; 2018 Sep 05; 157():1068-1080. PubMed ID: 30176537
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and biological evaluation of 1-(benzofuran-3-yl)-4-(3,4,5-trimethoxyphenyl)-1H-1,2,3-triazole derivatives as tubulin polymerization inhibitors.
    Qi ZY, Hao SY, Tian HZ, Bian HL, Hui L, Chen SW.
    Bioorg Chem; 2020 Jan 05; 94():103392. PubMed ID: 31669093
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and biological evaluation of N-substituted 3-oxo-1,2,3,4-tetrahydro-quinoxaline-6-carboxylic acid derivatives as tubulin polymerization inhibitors.
    Qi J, Dong H, Huang J, Zhang S, Niu L, Zhang Y, Wang J.
    Eur J Med Chem; 2018 Jan 01; 143():8-20. PubMed ID: 29172084
    [Abstract] [Full Text] [Related]

  • 13. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
    Romagnoli R, Kimatrai Salvador M, Schiaffino Ortega S, Baraldi PG, Oliva P, Baraldi S, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Balzarini J, Liekens S, Mattiuzzo E, Basso G, Viola G.
    Eur J Med Chem; 2018 Jan 01; 143():683-698. PubMed ID: 29220790
    [Abstract] [Full Text] [Related]

  • 14. Synthesis of substituted biphenyl methylene indolinones as apoptosis inducers and tubulin polymerization inhibitors.
    Donthiboina K, Anchi P, Sri Ramya PV, Karri S, Srinivasulu G, Godugu C, Shankaraiah N, Kamal A.
    Bioorg Chem; 2019 May 01; 86():210-223. PubMed ID: 30716619
    [Abstract] [Full Text] [Related]

  • 15. Design, Synthesis, and Evaluation of in Vitro and in Vivo Anticancer Activity of 4-Substituted Coumarins: A Novel Class of Potent Tubulin Polymerization Inhibitors.
    Cao D, Liu Y, Yan W, Wang C, Bai P, Wang T, Tang M, Wang X, Yang Z, Ma B, Ma L, Lei L, Wang F, Xu B, Zhou Y, Yang T, Chen L.
    J Med Chem; 2016 Jun 23; 59(12):5721-39. PubMed ID: 27213819
    [Abstract] [Full Text] [Related]

  • 16. Synthesis, in vitro and in vivo evaluation of new hybrids of millepachine and phenstatin as potent tubulin polymerization inhibitors.
    An B, Zhang S, Yan J, Huang L, Li X.
    Org Biomol Chem; 2017 Jan 25; 15(4):852-862. PubMed ID: 28009925
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis of combretastatin A-4 piperazine derivatives as potential antitumor agents by inhibiting tubulin polymerization and inducing autophagy in HCT116 cells.
    Zhang H, Li M, Zhou X, Tang L, Chen G, Zhang Y.
    Eur J Med Chem; 2024 Jun 05; 272():116497. PubMed ID: 38759453
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and evaluation of N-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)nicotinamides as potential anticancer agents that inhibit tubulin polymerization.
    Kamal A, Reddy NV, Nayak VL, Bolla NR, Subba Rao AV, Prasad B.
    Bioorg Med Chem; 2014 Jul 01; 22(13):3465-77. PubMed ID: 24835786
    [Abstract] [Full Text] [Related]

  • 19. Novel diaryl-2H-azirines: Antitumor hybrids for dual-targeting tubulin and DNA.
    Lin S, Liang Y, Cheng J, Pan F, Wang Y.
    Eur J Med Chem; 2021 Mar 15; 214():113256. PubMed ID: 33581556
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
    Zhou P, Liang Y, Zhang H, Jiang H, Feng K, Xu P, Wang J, Wang X, Ding K, Luo C, Liu M, Wang Y.
    Eur J Med Chem; 2018 Jan 20; 144():817-842. PubMed ID: 29306206
    [Abstract] [Full Text] [Related]

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