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184 related items for PubMed ID: 31612813

  • 1. Pegylation and Cell Based Bioassay of Human Interferon-α2b Along its Docking Studies and Effect on Plasma Half-Life.
    Shahzadi SK, Qadir MA, Mahmood N, Ahmed M.
    Protein Pept Lett; 2020; 27(3):219-224. PubMed ID: 31612813
    [Abstract] [Full Text] [Related]

  • 2. Site of pegylation and polyethylene glycol molecule size attenuate interferon-alpha antiviral and antiproliferative activities through the JAK/STAT signaling pathway.
    Grace MJ, Lee S, Bradshaw S, Chapman J, Spond J, Cox S, Delorenzo M, Brassard D, Wylie D, Cannon-Carlson S, Cullen C, Indelicato S, Voloch M, Bordens R.
    J Biol Chem; 2005 Feb 25; 280(8):6327-36. PubMed ID: 15596441
    [Abstract] [Full Text] [Related]

  • 3. PEGylated interferon-alpha2b: a branched 40K polyethylene glycol derivative.
    Ramon J, Saez V, Baez R, Aldana R, Hardy E.
    Pharm Res; 2005 Aug 25; 22(8):1374-86. PubMed ID: 16078148
    [Abstract] [Full Text] [Related]

  • 4. Enhanced circulating half-life and antitumor activity of a site-specific pegylated interferon-alpha protein therapeutic.
    Bell SJ, Fam CM, Chlipala EA, Carlson SJ, Lee JI, Rosendahl MS, Doherty DH, Cox GN.
    Bioconjug Chem; 2008 Jan 25; 19(1):299-305. PubMed ID: 18020402
    [Abstract] [Full Text] [Related]

  • 5. Structural and biologic characterization of pegylated recombinant IFN-alpha2b.
    Grace M, Youngster S, Gitlin G, Sydor W, Xie L, Westreich L, Jacobs S, Brassard D, Bausch J, Bordens R.
    J Interferon Cytokine Res; 2001 Dec 25; 21(12):1103-15. PubMed ID: 11798469
    [Abstract] [Full Text] [Related]

  • 6. A long-acting, highly potent interferon alpha-2 conjugate created using site-specific PEGylation.
    Rosendahl MS, Doherty DH, Smith DJ, Carlson SJ, Chlipala EA, Cox GN.
    Bioconjug Chem; 2005 Dec 25; 16(1):200-7. PubMed ID: 15656592
    [Abstract] [Full Text] [Related]

  • 7. Biologic activity of polyethylene glycol12000-interferon-alpha2b compared with interferon-alpha2b: gene modulatory and antigrowth effects in tumor cells.
    Vyas K, Brassard DL, DeLorenzo MM, Sun Y, Grace MJ, Borden EC, Leaman DW.
    J Immunother; 2003 Dec 25; 26(3):202-11. PubMed ID: 12806274
    [Abstract] [Full Text] [Related]

  • 8. Optimal PEGylation can improve the exposure of interferon in the lungs following pulmonary administration.
    Mcleod VM, Chan LJ, Ryan GM, Porter CJ, Kaminskas LM.
    J Pharm Sci; 2015 Apr 25; 104(4):1421-30. PubMed ID: 25631360
    [Abstract] [Full Text] [Related]

  • 9. Development of next generation of therapeutic IFN-α2b via genetic code expansion.
    Zhang B, Xu H, Chen J, Zheng Y, Wu Y, Si L, Wu L, Zhang C, Xia G, Zhang L, Zhou D.
    Acta Biomater; 2015 Jun 25; 19():100-11. PubMed ID: 25769229
    [Abstract] [Full Text] [Related]

  • 10. Development and biological activity of long-acting recombinant human interferon-α2b.
    Zhang Q, Wang C, Ma F, Yao L, Gao H, Zhu L, Zheng L.
    BMC Biotechnol; 2020 Mar 13; 20(1):16. PubMed ID: 32169063
    [Abstract] [Full Text] [Related]

  • 11. [Interferon alpha-2b modified with polyethylene glycol].
    Wu Y, Zhai Y, Lei J, Ma G, Su Z.
    Sheng Wu Gong Cheng Xue Bao; 2008 Sep 13; 24(9):1658-63. PubMed ID: 19160853
    [Abstract] [Full Text] [Related]

  • 12. A new method to produce monoPEGylated dimeric cytokines shown with human interferon-α2b.
    Chang CH, Rossi EA, Cardillo TM, Nordstrom DL, McBride WJ, Goldenberg DM.
    Bioconjug Chem; 2009 Oct 21; 20(10):1899-907. PubMed ID: 19736932
    [Abstract] [Full Text] [Related]

  • 13. Conjugation of PolyPEG to interferon alpha extends serum half-life while maintaining low viscosity of the conjugate.
    Podobnik B, Helk B, Smilović V, Škrajnar Š, Fidler K, Jevševar S, Godwin A, Williams P.
    Bioconjug Chem; 2015 Mar 18; 26(3):452-9. PubMed ID: 25629733
    [Abstract] [Full Text] [Related]

  • 14. Distinct hepatitis C virus kinetics in HIV-infected patients treated with ribavirin plus either pegylated interferon alpha2a or alpha2b.
    Vispo E, Barreiro P, Rodriguez-Nóvoa S, Morello J, Labarga P, Martín-Carbonero L, Maida I, García-Gascó P, Soriano V.
    Antivir Ther; 2008 Mar 18; 13(4):511-7. PubMed ID: 18672529
    [Abstract] [Full Text] [Related]

  • 15. A Highly Bioactive Lys-Deficient IFN Leads to a Site-Specific Di-PEGylated IFN with Equivalent Bioactivity to That of Unmodified IFN-α2b.
    Imada T, Moriya K, Uchiyama M, Inukai N, Hitotsuyanagi M, Masuda A, Suzuki T, Ayukawa S, Tagawa YI, Dohmae N, Kohara M, Yamamura M, Kiga D.
    ACS Synth Biol; 2018 Nov 16; 7(11):2537-2546. PubMed ID: 30277749
    [Abstract] [Full Text] [Related]

  • 16. PEGylated recombinant human interferon-ω as a long-acting antiviral agent: structure, antiviral activity and pharmacokinetics.
    Yu W, Yu C, Wu L, Fang T, Qiu R, Zhang J, Yu T, Fu L, Chen W, Hu T.
    Antiviral Res; 2014 Aug 16; 108():142-7. PubMed ID: 24936771
    [Abstract] [Full Text] [Related]

  • 17. Pegylated interferon-alpha2b: pharmacokinetics, pharmacodynamics, safety, and preliminary efficacy data. Hepatitis C Intervention Therapy Group.
    Glue P, Fang JW, Rouzier-Panis R, Raffanel C, Sabo R, Gupta SK, Salfi M, Jacobs S.
    Clin Pharmacol Ther; 2000 Nov 16; 68(5):556-67. PubMed ID: 11103758
    [Abstract] [Full Text] [Related]

  • 18. Evaluation of a single amino acid substitution at position 79 of human IFN-α2b in interferon-receptor assembly and activity.
    Talebi S, Saeedinia A, Zeinoddini M, Ahmadpour F, Sadeghizadeh M.
    Prep Biochem Biotechnol; 2019 Nov 16; 49(8):735-743. PubMed ID: 31135267
    [Abstract] [Full Text] [Related]

  • 19. Effects of pegylated interferon α2b on metastasis of hepatocellular carcinoma.
    Arakawa Y, Shimada M, Utsunomiya T, Imura S, Morine Y, Ikemoto T.
    J Surg Res; 2012 Jan 16; 172(1):95-101. PubMed ID: 20851413
    [Abstract] [Full Text] [Related]

  • 20. Pegylation of IFN-alpha and antiviral activity.
    Boulestin A, Kamar N, Sandres-Sauné K, Alric L, Vinel JP, Rostaing L, Izopet J.
    J Interferon Cytokine Res; 2006 Dec 16; 26(12):849-53. PubMed ID: 17238827
    [Abstract] [Full Text] [Related]

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