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232 related items for PubMed ID: 31645677

  • 1. EBV BCL-2 homologue BHRF1 drives chemoresistance and lymphomagenesis by inhibiting multiple cellular pro-apoptotic proteins.
    Fitzsimmons L, Cartlidge R, Chang C, Sejic N, Galbraith LCA, Suraweera CD, Croom-Carter D, Dewson G, Tierney RJ, Bell AI, Shannon-Lowe C, Herold MJ, Rickinson AB, Colman PM, Huang DCS, Strasser A, Kvansakul M, Rowe M, Kelly GL.
    Cell Death Differ; 2020 May; 27(5):1554-1568. PubMed ID: 31645677
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  • 2. Structural basis for apoptosis inhibition by Epstein-Barr virus BHRF1.
    Kvansakul M, Wei AH, Fletcher JI, Willis SN, Chen L, Roberts AW, Huang DC, Colman PM.
    PLoS Pathog; 2010 Dec 23; 6(12):e1001236. PubMed ID: 21203485
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  • 3. Epstein-Barr virus-encoded Bcl-2 homologue functions as a survival factor in Wp-restricted Burkitt lymphoma cell line P3HR-1.
    Watanabe A, Maruo S, Ito T, Ito M, Katsumura KR, Takada K.
    J Virol; 2010 Mar 23; 84(6):2893-901. PubMed ID: 20042495
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  • 4. Crystal Structures of Epstein-Barr Virus Bcl-2 Homolog BHRF1 Bound to Bid and Puma BH3 Motif Peptides.
    Suraweera CD, Hinds MG, Kvansakul M.
    Viruses; 2022 Oct 09; 14(10):. PubMed ID: 36298777
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  • 6. Crystallization and preliminary X-ray characterization of Epstein-Barr virus BHRF1 in complex with a benzoylurea peptidomimetic.
    Caria S, Chugh S, Nhu D, Lessene G, Kvansakul M.
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2012 Dec 01; 68(Pt 12):1521-4. PubMed ID: 23192038
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  • 9. Combination of SAHA and bortezomib up-regulates CDKN2A and CDKN1A and induces apoptosis of Epstein-Barr virus-positive Wp-restricted Burkitt lymphoma and lymphoblastoid cell lines.
    Hui KF, Leung YY, Yeung PL, Middeldorp JM, Chiang AK.
    Br J Haematol; 2014 Dec 01; 167(5):639-50. PubMed ID: 25155625
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  • 10. BHRF1, a viral homologue of the Bcl-2 oncogene, is conserved at both the sequence and functional level in different Epstein-Barr virus isolates.
    Khanim F, Dawson C, Meseda CA, Dawson J, Mackett M, Young LS.
    J Gen Virol; 1997 Nov 01; 78 ( Pt 11)():2987-99. PubMed ID: 9367386
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  • 11. Solution structure of the BHRF1 protein from Epstein-Barr virus, a homolog of human Bcl-2.
    Huang Q, Petros AM, Virgin HW, Fesik SW, Olejniczak ET.
    J Mol Biol; 2003 Oct 03; 332(5):1123-30. PubMed ID: 14499614
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  • 12. The Epstein-Barr virus Bcl-2 homolog, BHRF1, blocks apoptosis by binding to a limited amount of Bim.
    Desbien AL, Kappler JW, Marrack P.
    Proc Natl Acad Sci U S A; 2009 Apr 07; 106(14):5663-8. PubMed ID: 19293378
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  • 14. BHRF1 exerts an antiapoptotic effect and cell cycle arrest via Bcl-2 in murine hybridomas.
    Milián E, Prats E, Cairó JJ, Gòdia F, Vives J.
    J Biotechnol; 2015 Sep 10; 209():58-67. PubMed ID: 26057602
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  • 16. Epstein-Barr virus (EBV) nuclear antigen leader protein (EBNA-LP) forms complexes with a cellular anti-apoptosis protein Bcl-2 or its EBV counterpart BHRF1 through HS1-associated protein X-1.
    Matsuda G, Nakajima K, Kawaguchi Y, Yamanashi Y, Hirai K.
    Microbiol Immunol; 2003 Sep 10; 47(1):91-9. PubMed ID: 12636258
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  • 17. Expression of the Epstein-Barr virus BHRF1 gene, a homologue of Bcl-2, in nasopharyngeal carcinoma tissue.
    Liu MY, Shih YY, Li LY, Chou SP, Sheen TS, Chen CL, Yang CS, Chen JY.
    J Med Virol; 2000 Jun 10; 61(2):241-50. PubMed ID: 10797381
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  • 18. Herpesvirus papio encodes a functional homologue of the Epstein-Barr virus apoptosis suppressor, BHRF1.
    Meseda CA, Arrand JR, Mackett M.
    J Gen Virol; 2000 Jul 10; 81(Pt 7):1801-5. PubMed ID: 10859386
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  • 19. Lymphoma cells lacking pro-apoptotic BAX are highly resistant to BH3-mimetics targeting pro-survival MCL-1 but retain sensitivity to conventional DNA-damaging drugs.
    Diepstraten ST, Young S, La Marca JE, Wang Z, Kluck RM, Strasser A, Kelly GL.
    Cell Death Differ; 2023 Apr 10; 30(4):1005-1017. PubMed ID: 36755070
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  • 20. Bim must be able to engage all pro-survival Bcl-2 family members for efficient tumor suppression.
    Mérino D, Strasser A, Bouillet P.
    Oncogene; 2012 Jul 12; 31(28):3392-6. PubMed ID: 22081075
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