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869 related items for PubMed ID: 31669234
1. Delicaflavone induces ROS-mediated apoptosis and inhibits PI3K/AKT/mTOR and Ras/MEK/Erk signaling pathways in colorectal cancer cells. Yao W, Lin Z, Shi P, Chen B, Wang G, Huang J, Sui Y, Liu Q, Li S, Lin X, Liu Q, Yao H. Biochem Pharmacol; 2020 Jan; 171():113680. PubMed ID: 31669234 [Abstract] [Full Text] [Related]
2. Delicaflavone induces apoptosis via mitochondrial pathway accompanying G2/M cycle arrest and inhibition of MAPK signaling cascades in cervical cancer HeLa cells. Yao W, Lin Z, Wang G, Li S, Chen B, Sui Y, Huang J, Liu Q, Shi P, Lin X, Liu Q, Yao H. Phytomedicine; 2019 Sep; 62():152973. PubMed ID: 31177019 [Abstract] [Full Text] [Related]
3. Deoxyshikonin isolated from Arnebia euchroma inhibits colorectal cancer by down-regulating the PI3K/Akt/mTOR pathway. Zhu Y, Zhong Y, Long X, Zhu Z, Zhou Y, Ye H, Zeng X, Zheng X. Pharm Biol; 2019 Dec; 57(1):412-423. PubMed ID: 31230505 [Abstract] [Full Text] [Related]
4. Zeylenone, a naturally occurring cyclohexene oxide, inhibits proliferation and induces apoptosis in cervical carcinoma cells via PI3K/AKT/mTOR and MAPK/ERK pathways. Zhang L, Huo X, Liao Y, Yang F, Gao L, Cao L. Sci Rep; 2017 May 10; 7(1):1669. PubMed ID: 28490807 [Abstract] [Full Text] [Related]
5. Delicaflavone induces autophagic cell death in lung cancer via Akt/mTOR/p70S6K signaling pathway. Sui Y, Yao H, Li S, Jin L, Shi P, Li Z, Wang G, Lin S, Wu Y, Li Y, Huang L, Liu Q, Lin X. J Mol Med (Berl); 2017 Mar 10; 95(3):311-322. PubMed ID: 27838742 [Abstract] [Full Text] [Related]
6. Atractylenolide I inhibits colorectal cancer cell proliferation by affecting metabolism and stemness via AKT/mTOR signaling. Wang K, Huang W, Sang X, Wu X, Shan Q, Tang D, Xu X, Cao G. Phytomedicine; 2020 Mar 10; 68():153191. PubMed ID: 32135457 [Abstract] [Full Text] [Related]
7. Synthetic lethal interaction between PI3K/Akt/mTOR and Ras/MEK/ERK pathway inhibition in rhabdomyosarcoma. Guenther MK, Graab U, Fulda S. Cancer Lett; 2013 Sep 01; 337(2):200-9. PubMed ID: 23684925 [Abstract] [Full Text] [Related]
8. Des-gamma-carboxy prothrombin antagonizes the effects of Sorafenib on human hepatocellular carcinoma through activation of the Raf/MEK/ERK and PI3K/Akt/mTOR signaling pathways. Cui SX, Shi WN, Song ZY, Wang SQ, Yu XF, Gao ZH, Qu XJ. Oncotarget; 2016 Jun 14; 7(24):36767-36782. PubMed ID: 27167344 [Abstract] [Full Text] [Related]
9. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway. Niu NK, Wang ZL, Pan ST, Ding HQ, Au GH, He ZX, Zhou ZW, Xiao G, Yang YX, Zhang X, Yang T, Chen XW, Qiu JX, Zhou SF. Drug Des Devel Ther; 2015 Jun 14; 9():1555-84. PubMed ID: 25792811 [Abstract] [Full Text] [Related]
10. Linalool induces cell cycle arrest and apoptosis in HepG2 cells through oxidative stress generation and modulation of Ras/MAPK and Akt/mTOR pathways. Rodenak-Kladniew B, Castro A, Stärkel P, De Saeger C, García de Bravo M, Crespo R. Life Sci; 2018 Apr 15; 199():48-59. PubMed ID: 29510199 [Abstract] [Full Text] [Related]
11. Coptisine-induced apoptosis in human colon cancer cells (HCT-116) is mediated by PI3K/Akt and mitochondrial-associated apoptotic pathway. Han B, Jiang P, Li Z, Yu Y, Huang T, Ye X, Li X. Phytomedicine; 2018 Sep 15; 48():152-160. PubMed ID: 30195873 [Abstract] [Full Text] [Related]
12. NSK-01105 inhibits proliferation and induces apoptosis of prostate cancer cells by blocking the Raf/MEK/ERK and PI3K/Akt/mTOR signal pathways. Yu P, Ye L, Wang H, Du G, Zhang J, Zhang J, Tian J. Tumour Biol; 2015 Mar 15; 36(3):2143-53. PubMed ID: 25398692 [Abstract] [Full Text] [Related]
13. Antitumor activity of pimasertib, a selective MEK 1/2 inhibitor, in combination with PI3K/mTOR inhibitors or with multi-targeted kinase inhibitors in pimasertib-resistant human lung and colorectal cancer cells. Martinelli E, Troiani T, D'Aiuto E, Morgillo F, Vitagliano D, Capasso A, Costantino S, Ciuffreda LP, Merolla F, Vecchione L, De Vriendt V, Tejpar S, Nappi A, Sforza V, Martini G, Berrino L, De Palma R, Ciardiello F. Int J Cancer; 2013 Nov 15; 133(9):2089-101. PubMed ID: 23629727 [Abstract] [Full Text] [Related]
14. Ethyl acetate extract from Selaginella doederleinii Hieron inhibits the growth of human lung cancer cells A549 via caspase-dependent apoptosis pathway. Sui Y, Li S, Shi P, Wu Y, Li Y, Chen W, Huang L, Yao H, Lin X. J Ethnopharmacol; 2016 Aug 22; 190():261-71. PubMed ID: 27292193 [Abstract] [Full Text] [Related]
15. Inhibition of Autophagy Promotes Salinomycin-Induced Apoptosis via Reactive Oxygen Species-Mediated PI3K/AKT/mTOR and ERK/p38 MAPK-Dependent Signaling in Human Prostate Cancer Cells. Kim KY, Park KI, Kim SH, Yu SN, Park SG, Kim YW, Seo YK, Ma JY, Ahn SC. Int J Mol Sci; 2017 May 18; 18(5):. PubMed ID: 28524116 [Abstract] [Full Text] [Related]
16. Lycorine inhibits cell proliferation, migration and invasion, and primarily exerts in vitro cytostatic effects in human colorectal cancer via activating the ROS/p38 and AKT signaling pathways. Zhang P, Yuan X, Yu T, Huang H, Yang C, Zhang L, Yang S, Luo X, Luo J. Oncol Rep; 2021 Apr 18; 45(4):. PubMed ID: 33649853 [Abstract] [Full Text] [Related]
17. PI3K/Akt/mTOR and Ras/Raf/MEK/ERK signaling pathways inhibitors as anticancer agents: Structural and pharmacological perspectives. Asati V, Mahapatra DK, Bharti SK. Eur J Med Chem; 2016 Feb 15; 109():314-41. PubMed ID: 26807863 [Abstract] [Full Text] [Related]
18. Piperlongumine, a piper alkaloid targets Ras/PI3K/Akt/mTOR signaling axis to inhibit tumor cell growth and proliferation in DMH/DSS induced experimental colon cancer. Kumar S, Agnihotri N. Biomed Pharmacother; 2019 Jan 15; 109():1462-1477. PubMed ID: 30551398 [Abstract] [Full Text] [Related]
19. A network pharmacology approach and experimental validation to investigate the anticancer mechanism and potential active targets of ethanol extract of Wei-Tong-Xin against colorectal cancer through induction of apoptosis via PI3K/AKT signaling pathway. Lin F, Zhang G, Yang X, Wang M, Wang R, Wan M, Wang J, Wu B, Yan T, Jia Y. J Ethnopharmacol; 2023 Mar 01; 303():115933. PubMed ID: 36403742 [Abstract] [Full Text] [Related]
20. AMP-kinase inhibitor dorsomorphin reduces the proliferation and migration behavior of colorectal cancer cells by targeting the AKT/mTOR pathway. Ghanaatgar-Kasbi S, Amerizadeh F, Rahmani F, Hassanian SM, Khazaei M, Ferns GA, Avan A. IUBMB Life; 2019 Dec 01; 71(12):1929-1936. PubMed ID: 31359579 [Abstract] [Full Text] [Related] Page: [Next] [New Search]