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Journal Abstract Search

505 related items for PubMed ID: 31675998

  • 1. Dietary-phytochemical mediated reversion of cancer-specific splicing inhibits Warburg effect in head and neck cancer.
    Yadav S, Bhagat SD, Gupta A, Samaiya A, Srivastava A, Shukla S.
    BMC Cancer; 2019 Nov 01; 19(1):1031. PubMed ID: 31675998
    [Abstract] [Full Text] [Related]

  • 2. SAM68 promotes tumorigenesis in lung adenocarcinoma by regulating metabolic conversion via PKM alternative splicing.
    Zhu S, Chen W, Wang J, Qi L, Pan H, Feng Z, Tian D.
    Theranostics; 2021 Nov 01; 11(7):3359-3375. PubMed ID: 33537092
    [Abstract] [Full Text] [Related]

  • 3. Intragenic DNA methylation and BORIS-mediated cancer-specific splicing contribute to the Warburg effect.
    Singh S, Narayanan SP, Biswas K, Gupta A, Ahuja N, Yadav S, Panday RK, Samaiya A, Sharan SK, Shukla S.
    Proc Natl Acad Sci U S A; 2017 Oct 24; 114(43):11440-11445. PubMed ID: 29073069
    [Abstract] [Full Text] [Related]

  • 4. Tissue-specific isoform switch and DNA hypomethylation of the pyruvate kinase PKM gene in human cancers.
    Desai S, Ding M, Wang B, Lu Z, Zhao Q, Shaw K, Yung WK, Weinstein JN, Tan M, Yao J.
    Oncotarget; 2014 Sep 30; 5(18):8202-10. PubMed ID: 24077665
    [Abstract] [Full Text] [Related]

  • 5. Organ-Specific MicroRNAs (MIR122, 137, and 206) Contribute to Tissue Characteristics and Carcinogenesis by Regulating Pyruvate Kinase M1/2 (PKM) Expression.
    Taniguchi K, Sugito N, Shinohara H, Kuranaga Y, Inomata Y, Komura K, Uchiyama K, Akao Y.
    Int J Mol Sci; 2018 Apr 24; 19(5):. PubMed ID: 29695138
    [Abstract] [Full Text] [Related]

  • 6. Isoform switch of pyruvate kinase M1 indeed occurs but not to pyruvate kinase M2 in human tumorigenesis.
    Zhan C, Yan L, Wang L, Ma J, Jiang W, Zhang Y, Shi Y, Wang Q.
    PLoS One; 2015 Apr 24; 10(3):e0118663. PubMed ID: 25738776
    [Abstract] [Full Text] [Related]

  • 7. Pyruvate kinase M knockdown-induced signaling via AMP-activated protein kinase promotes mitochondrial biogenesis, autophagy, and cancer cell survival.
    Prakasam G, Singh RK, Iqbal MA, Saini SK, Tiku AB, Bamezai RNK.
    J Biol Chem; 2017 Sep 15; 292(37):15561-15576. PubMed ID: 28778925
    [Abstract] [Full Text] [Related]

  • 8. miR-124, miR-137 and miR-340 regulate colorectal cancer growth via inhibition of the Warburg effect.
    Sun Y, Zhao X, Zhou Y, Hu Y.
    Oncol Rep; 2012 Oct 15; 28(4):1346-52. PubMed ID: 22895557
    [Abstract] [Full Text] [Related]

  • 9. No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis.
    Bluemlein K, Grüning NM, Feichtinger RG, Lehrach H, Kofler B, Ralser M.
    Oncotarget; 2011 May 15; 2(5):393-400. PubMed ID: 21789790
    [Abstract] [Full Text] [Related]

  • 10. PAK2-c-Myc-PKM2 axis plays an essential role in head and neck oncogenesis via regulating Warburg effect.
    Gupta A, Ajith A, Singh S, Panday RK, Samaiya A, Shukla S.
    Cell Death Dis; 2018 Aug 01; 9(8):825. PubMed ID: 30068946
    [Abstract] [Full Text] [Related]

  • 11. Organ-specific PTB1-associated microRNAs determine expression of pyruvate kinase isoforms.
    Taniguchi K, Ito Y, Sugito N, Kumazaki M, Shinohara H, Yamada N, Nakagawa Y, Sugiyama T, Futamura M, Otsuki Y, Yoshida K, Uchiyama K, Akao Y.
    Sci Rep; 2015 Feb 27; 5():8647. PubMed ID: 25721733
    [Abstract] [Full Text] [Related]

  • 12. ASO-Based PKM Splice-Switching Therapy Inhibits Hepatocellular Carcinoma Growth.
    Ma WK, Voss DM, Scharner J, Costa ASH, Lin KT, Jeon HY, Wilkinson JE, Jackson M, Rigo F, Bennett CF, Krainer AR.
    Cancer Res; 2022 Mar 01; 82(5):900-915. PubMed ID: 34921016
    [Abstract] [Full Text] [Related]

  • 13. Oleanolic acid suppresses aerobic glycolysis in cancer cells by switching pyruvate kinase type M isoforms.
    Liu J, Wu N, Ma L, Liu M, Liu G, Zhang Y, Lin X.
    PLoS One; 2014 Mar 01; 9(3):e91606. PubMed ID: 24626155
    [Abstract] [Full Text] [Related]

  • 14. A novel miR-206/hnRNPA1/PKM2 axis reshapes the Warburg effect to suppress colon cancer growth.
    Fu R, Yang P, Amin S, Li Z.
    Biochem Biophys Res Commun; 2020 Oct 22; 531(4):465-471. PubMed ID: 32800545
    [Abstract] [Full Text] [Related]

  • 15. Base editing-mediated perturbation of endogenous PKM1/2 splicing facilitates isoform-specific functional analysis in vitro and in vivo.
    Lin J, Wu S, Shen Q, Liu J, Huang S, Peng G, Qiao Y.
    Cell Prolif; 2021 Aug 22; 54(8):e13096. PubMed ID: 34240779
    [Abstract] [Full Text] [Related]

  • 16. Tumor suppressor SMAR1 regulates PKM alternative splicing by HDAC6-mediated deacetylation of PTBP1.
    Choksi A, Parulekar A, Pant R, Shah VK, Nimma R, Firmal P, Singh S, Kundu GC, Shukla S, Chattopadhyay S.
    Cancer Metab; 2021 Apr 16; 9(1):16. PubMed ID: 33863392
    [Abstract] [Full Text] [Related]

  • 17. Preventing pyruvate kinase muscle expression in Chinese hamster ovary cells curbs lactogenic behavior by altering glycolysis, gating pyruvate generation, and increasing pyruvate flux into the TCA cycle.
    Tang D, Sandoval W, Liu P, Lam C, Snedecor B, Misaghi S.
    Biotechnol Prog; 2021 Sep 16; 37(5):e3193. PubMed ID: 34288605
    [Abstract] [Full Text] [Related]

  • 18. The cysteine residue at 424th of pyruvate kinase M2 is crucial for tetramerization and responsiveness to oxidative stress.
    Masaki S, Hashimoto K, Kihara D, Tsuzuki C, Kataoka N, Suzuki K.
    Biochem Biophys Res Commun; 2020 Jun 11; 526(4):973-977. PubMed ID: 32295714
    [Abstract] [Full Text] [Related]

  • 19. HNRNPC modulates PKM alternative splicing via m6A methylation, upregulating PKM2 expression to promote aerobic glycolysis in papillary thyroid carcinoma and drive malignant progression.
    Rong S, Dai B, Yang C, Lan Z, Wang L, Xu L, Chen W, Chen J, Wu Z.
    J Transl Med; 2024 Oct 08; 22(1):914. PubMed ID: 39380010
    [Abstract] [Full Text] [Related]

  • 20. PKM2, cancer metabolism, and the road ahead.
    Dayton TL, Jacks T, Vander Heiden MG.
    EMBO Rep; 2016 Dec 08; 17(12):1721-1730. PubMed ID: 27856534
    [Abstract] [Full Text] [Related]

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