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Journal Abstract Search

339 related items for PubMed ID: 31679839

  • 1. Fluorinated 3,6,9-trisubstituted acridine derivatives as DNA interacting agents and topoisomerase inhibitors with A549 antiproliferative activity.
    Nunhart P, Konkoľová E, Janovec L, Jendželovský R, Vargová J, Ševc J, Matejová M, Miltáková B, Fedoročko P, Kozurkova M.
    Bioorg Chem; 2020 Jan; 94():103393. PubMed ID: 31679839
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of DNA topoisomerases I and II and growth inhibition of HL-60 cells by novel acridine-based compounds.
    Janočková J, Plšíková J, Kašpárková J, Brabec V, Jendželovský R, Mikeš J, Kovaľ J, Hamuľaková S, Fedoročko P, Kuča K, Kožurková M.
    Eur J Pharm Sci; 2015 Aug 30; 76():192-202. PubMed ID: 25960253
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and antiproliferative activity of 9-benzylamino-6-chloro-2-methoxy-acridine derivatives as potent DNA-binding ligands and topoisomerase II inhibitors.
    Zhang W, Zhang B, Zhang W, Yang T, Wang N, Gao C, Tan C, Liu H, Jiang Y.
    Eur J Med Chem; 2016 Jun 30; 116():59-70. PubMed ID: 27060757
    [Abstract] [Full Text] [Related]

  • 4. Tacrine-Coumarin Derivatives as Topoisomerase Inhibitors with Antitumor Effects on A549 Human Lung Carcinoma Cancer Cell Lines.
    Konkoľová E, Hudáčová M, Hamuľaková S, Jendželovský R, Vargová J, Ševc J, Fedoročko P, Kožurková M.
    Molecules; 2021 Feb 20; 26(4):. PubMed ID: 33672694
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and biological evaluation of benzo[a]phenazine derivatives as a dual inhibitor of topoisomerase I and II.
    Zhuo ST, Li CY, Hu MH, Chen SB, Yao PF, Huang SL, Ou TM, Tan JH, An LK, Li D, Gu LQ, Huang ZS.
    Org Biomol Chem; 2013 Jun 28; 11(24):3989-4005. PubMed ID: 23657605
    [Abstract] [Full Text] [Related]

  • 6. Design and Synthesis of Arylnaphthalene Lignan Lactone Derivatives as Potent Topoisomerase Inhibitors.
    Chen W, Feng Z, Hu D, Meng J.
    Med Chem; 2021 Jun 28; 17(8):856-865. PubMed ID: 32520691
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and biological evaluation of N-substituted benzo[c]phenanthrolines and benzo[c]phenanthrolinones as antiproliferative agents.
    Genès C, Lenglet G, Depauw S, Nhili R, Prado S, David-Cordonnier MH, Michel S, Tillequin F, Porée FH.
    Eur J Med Chem; 2011 Jun 28; 46(6):2117-31. PubMed ID: 21435753
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis and systematic evaluation of cytotoxic 3-heteroarylisoquinolinamines as topoisomerases inhibitors.
    My Van HT, Woo H, Jeong HM, Khadka DB, Yang SH, Zhao C, Jin Y, Lee ES, Youl Lee K, Kwon Y, Cho WJ.
    Eur J Med Chem; 2014 Jul 23; 82():181-94. PubMed ID: 24904965
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and biological research of novel azaacridine derivatives as potent DNA-binding ligands and topoisomerase II inhibitors.
    Li D, Yuan Z, Chen S, Zhang C, Song L, Gao C, Chen Y, Tan C, Jiang Y.
    Bioorg Med Chem; 2017 Jul 01; 25(13):3437-3446. PubMed ID: 28511910
    [Abstract] [Full Text] [Related]

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  • 11. Design, synthesis and biological evaluation of novel 7-alkylamino substituted benzo[a]phenazin derivatives as dual topoisomerase I/II inhibitors.
    Yao BL, Mai YW, Chen SB, Xie HT, Yao PF, Ou TM, Tan JH, Wang HG, Li D, Huang SL, Gu LQ, Huang ZS.
    Eur J Med Chem; 2015 Mar 06; 92():540-53. PubMed ID: 25599951
    [Abstract] [Full Text] [Related]

  • 12. Pyrroloquinolinone-based dual topoisomerase I/II inhibitor.
    Dalla Via L, Marzaro G, Ferrarese A, Gia O, Chilin A.
    Eur J Med Chem; 2014 Apr 22; 77():103-9. PubMed ID: 24631729
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and evaluation of novel ellipticines as potential anti-cancer agents.
    Deane FM, O'Sullivan EC, Maguire AR, Gilbert J, Sakoff JA, McCluskey A, McCarthy FO.
    Org Biomol Chem; 2013 Feb 28; 11(8):1334-44. PubMed ID: 23314103
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  • 16. Synthesis and biological evaluation of 2-phenol-4-chlorophenyl-6-aryl pyridines as topoisomerase II inhibitors and cytotoxic agents.
    Thapa P, Kadayat TM, Park S, Shin S, Thapa Magar TB, Bist G, Shrestha A, Na Y, Kwon Y, Lee ES.
    Bioorg Chem; 2016 Jun 28; 66():145-59. PubMed ID: 27174797
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  • 18. Rational design, synthesis, and evaluation of novel 2,4-Chloro- and Hydroxy-Substituted diphenyl Benzofuro[3,2-b]Pyridines: Non-intercalative catalytic topoisomerase I and II dual inhibitor.
    Park S, Thapa Magar TB, Kadayat TM, Lee HJ, Bist G, Shrestha A, Lee ES, Kwon Y.
    Eur J Med Chem; 2017 Feb 15; 127():318-333. PubMed ID: 28068603
    [Abstract] [Full Text] [Related]

  • 19. Synthesis, DNA and protein interactions and human topoisomerase inhibition of novel Spiroacridine derivatives.
    Gouveia RG, Ribeiro AG, Segundo MÂSP, de Oliveira JF, de Lima MDCA, de Lima Souza TRC, de Almeida SMV, de Moura RO.
    Bioorg Med Chem; 2018 Dec 01; 26(22):5911-5921. PubMed ID: 30420325
    [Abstract] [Full Text] [Related]

  • 20. Novel N-4-piperazinyl-ciprofloxacin-chalcone hybrids: synthesis, physicochemical properties, anticancer and topoisomerase I and II inhibitory activity.
    Abdel-Aziz M, Park SE, Abuo-Rahma Gel-D, Sayed MA, Kwon Y.
    Eur J Med Chem; 2013 Nov 01; 69():427-38. PubMed ID: 24090914
    [Abstract] [Full Text] [Related]

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