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Journal Abstract Search


258 related items for PubMed ID: 31696233

  • 1. Cerebellar contribution to the cognitive alterations in SCA1: evidence from mouse models.
    Asher M, Rosa JG, Rainwater O, Duvick L, Bennyworth M, Lai RY, CRC-SCA, Kuo SH, Cvetanovic M.
    Hum Mol Genet; 2020 Jan 01; 29(1):117-131. PubMed ID: 31696233
    [Abstract] [Full Text] [Related]

  • 2. Cerebellar contribution to cognitive deficits and prefrontal cortex dysfunction in Spinocerebellar Ataxia Type 1 (SCA1).
    Sbrocco K, Borgenheimer E, Zhang Y, Koob M, Cvetanovic M.
    bioRxiv; 2024 Jul 10. PubMed ID: 39026827
    [Abstract] [Full Text] [Related]

  • 3. BDNF is altered in a brain-region specific manner and rescues deficits in Spinocerebellar Ataxia Type 1.
    Rosa JG, Hamel K, Soles A, Sheeler C, Borgenheimer E, Gilliat S, Sbrocco K, Ghanoum F, Handler HP, Forster C, Rainwater O, Cvetanovic M.
    Neurobiol Dis; 2023 Mar 10; 178():106023. PubMed ID: 36724861
    [Abstract] [Full Text] [Related]

  • 4. Decreasing mutant ATXN1 nuclear localization improves a spectrum of SCA1-like phenotypes and brain region transcriptomic profiles.
    Handler HP, Duvick L, Mitchell JS, Cvetanovic M, Reighard M, Soles A, Mather KB, Rainwater O, Serres S, Nichols-Meade T, Coffin SL, You Y, Ruis BL, O'Callaghan B, Henzler C, Zoghbi HY, Orr HT.
    Neuron; 2023 Feb 15; 111(4):493-507.e6. PubMed ID: 36577403
    [Abstract] [Full Text] [Related]

  • 5. Indirect Negative Effect of Mutant Ataxin-1 on Short- and Long-Term Synaptic Plasticity in Mouse Models of Spinocerebellar Ataxia Type 1.
    Shuvaev AN, Belozor OS, Mozhei OI, Shuvaev AN, Fritsler YV, Khilazheva ED, Mosyagina AI, Hirai H, Teschemacher AG, Kasparov S.
    Cells; 2022 Jul 20; 11(14):. PubMed ID: 35883691
    [Abstract] [Full Text] [Related]

  • 6. Modulation of ATXN1 S776 phosphorylation reveals the importance of allele-specific targeting in SCA1.
    Nitschke L, Coffin SL, Xhako E, El-Najjar DB, Orengo JP, Alcala E, Dai Y, Wan YW, Liu Z, Orr HT, Zoghbi HY.
    JCI Insight; 2021 Feb 08; 6(3):. PubMed ID: 33554954
    [Abstract] [Full Text] [Related]

  • 7. Mood alterations in mouse models of Spinocerebellar Ataxia type 1.
    Asher M, Rosa JG, Cvetanovic M.
    Sci Rep; 2021 Jan 12; 11(1):713. PubMed ID: 33436887
    [Abstract] [Full Text] [Related]

  • 8. Ataxin-1 regulates the cerebellar bioenergetics proteome through the GSK3β-mTOR pathway which is altered in Spinocerebellar ataxia type 1 (SCA1).
    Sánchez I, Balagué E, Matilla-Dueñas A.
    Hum Mol Genet; 2016 Sep 15; 25(18):4021-4040. PubMed ID: 27466200
    [Abstract] [Full Text] [Related]

  • 9. Ataxin-1 regulates proliferation of hippocampal neural precursors.
    Asher M, Johnson A, Zecevic B, Pease D, Cvetanovic M.
    Neuroscience; 2016 May 13; 322():54-65. PubMed ID: 26876606
    [Abstract] [Full Text] [Related]

  • 10. The extra-cerebellar effects of spinocerebellar ataxia type 1 (SCA1): looking beyond the cerebellum.
    Olmos V, Gogia N, Luttik K, Haidery F, Lim J.
    Cell Mol Life Sci; 2022 Jul 08; 79(8):404. PubMed ID: 35802260
    [Abstract] [Full Text] [Related]

  • 11. ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism.
    Rousseaux MWC, Tschumperlin T, Lu HC, Lackey EP, Bondar VV, Wan YW, Tan Q, Adamski CJ, Friedrich J, Twaroski K, Chen W, Tolar J, Henzler C, Sharma A, Bajić A, Lin T, Duvick L, Liu Z, Sillitoe RV, Zoghbi HY, Orr HT.
    Neuron; 2018 Mar 21; 97(6):1235-1243.e5. PubMed ID: 29526553
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of colony-stimulating factor 1 receptor early in disease ameliorates motor deficits in SCA1 mice.
    Qu W, Johnson A, Kim JH, Lukowicz A, Svedberg D, Cvetanovic M.
    J Neuroinflammation; 2017 May 25; 14(1):107. PubMed ID: 28545543
    [Abstract] [Full Text] [Related]

  • 13. Antisense oligonucleotide-mediated ataxin-1 reduction prolongs survival in SCA1 mice and reveals disease-associated transcriptome profiles.
    Friedrich J, Kordasiewicz HB, O'Callaghan B, Handler HP, Wagener C, Duvick L, Swayze EE, Rainwater O, Hofstra B, Benneyworth M, Nichols-Meade T, Yang P, Chen Z, Ortiz JP, Clark HB, Öz G, Larson S, Zoghbi HY, Henzler C, Orr HT.
    JCI Insight; 2018 Nov 02; 3(21):. PubMed ID: 30385727
    [Abstract] [Full Text] [Related]

  • 14. Sphingolipid metabolism governs Purkinje cell patterned degeneration in Atxn1[82Q]/+ mice.
    Blot FGC, Krijnen WHJJ, Den Hoedt S, Osório C, White JJ, Mulder MT, Schonewille M.
    Proc Natl Acad Sci U S A; 2021 Sep 07; 118(36):. PubMed ID: 34479994
    [Abstract] [Full Text] [Related]

  • 15. Cross-species genetic screens identify transglutaminase 5 as a regulator of polyglutamine-expanded ataxin-1.
    Lee WS, Al-Ramahi I, Jeong HH, Jang Y, Lin T, Adamski CJ, Lavery LA, Rath S, Richman R, Bondar VV, Alcala E, Revelli JP, Orr HT, Liu Z, Botas J, Zoghbi HY.
    J Clin Invest; 2022 May 02; 132(9):. PubMed ID: 35499073
    [Abstract] [Full Text] [Related]

  • 16. Non-invasive detection of neurochemical changes prior to overt pathology in a mouse model of spinocerebellar ataxia type 1.
    Emir UE, Brent Clark H, Vollmers ML, Eberly LE, Öz G.
    J Neurochem; 2013 Dec 02; 127(5):660-8. PubMed ID: 24032423
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