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465 related items for PubMed ID: 31703757

  • 1. Inhibitory effects of polyphyllins I and VII on human cisplatin-resistant NSCLC via p53 upregulation and CIP2A/AKT/mTOR signaling axis inhibition.
    Feng FF, Cheng P, Sun C, Wang H, Wang W.
    Chin J Nat Med; 2019 Oct; 17(10):768-777. PubMed ID: 31703757
    [Abstract] [Full Text] [Related]

  • 2. Polyphyllin I and VII potentiate the chemosensitivity of A549/DDP cells to cisplatin by enhancing apoptosis, reversing EMT and suppressing the CIP2A/AKT/mTOR signaling axis.
    Feng F, Cheng P, Wang C, Wang Y, Wang W.
    Oncol Lett; 2019 Nov; 18(5):5428-5436. PubMed ID: 31612051
    [Abstract] [Full Text] [Related]

  • 3. Polyphyllin I inhibits growth and invasion of cisplatin-resistant gastric cancer cells by partially inhibiting CIP2A/PP2A/Akt signaling axis.
    Zhang Y, Huang P, Liu X, Xiang Y, Zhang T, Wu Y, Xu J, Sun Z, Zhen W, Zhang L, Si Y, Liu Y.
    J Pharmacol Sci; 2018 Jul; 137(3):305-312. PubMed ID: 30119963
    [Abstract] [Full Text] [Related]

  • 4. Cucurbitacin B induces autophagy and apoptosis by suppressing CIP2A/PP2A/mTORC1 signaling axis in human cisplatin resistant gastric cancer cells.
    Liu X, Duan C, Ji J, Zhang T, Yuan X, Zhang Y, Ma W, Yang J, Yang L, Jiang Z, Yu H, Liu Y.
    Oncol Rep; 2017 Jul; 38(1):271-278. PubMed ID: 28534965
    [Abstract] [Full Text] [Related]

  • 5. Co-treatment with BEZ235 enhances chemosensitivity of A549/DDP cells to cisplatin via inhibition of PI3K/Akt/mTOR signaling and downregulation of ERCC1 expression.
    Xia A, Li H, Li R, Lu L, Wu X.
    Oncol Rep; 2018 Oct; 40(4):2353-2362. PubMed ID: 30066933
    [Abstract] [Full Text] [Related]

  • 6. Cucurbitacin B Induces the Lysosomal Degradation of EGFR and Suppresses the CIP2A/PP2A/Akt Signaling Axis in Gefitinib-Resistant Non-Small Cell Lung Cancer.
    Liu P, Xiang Y, Liu X, Zhang T, Yang R, Chen S, Xu L, Yu Q, Zhao H, Zhang L, Liu Y, Si Y.
    Molecules; 2019 Feb 12; 24(3):. PubMed ID: 30759826
    [Abstract] [Full Text] [Related]

  • 7. XPC inhibition rescues cisplatin resistance via the Akt/mTOR signaling pathway in A549/DDP lung adenocarcinoma cells.
    Teng X, Fan XF, Li Q, Liu S, Wu DY, Wang SY, Shi Y, Dong M.
    Oncol Rep; 2019 Mar 12; 41(3):1875-1882. PubMed ID: 30628719
    [Abstract] [Full Text] [Related]

  • 8. Knockdown of KLF5 suppresses hypoxia-induced resistance to cisplatin in NSCLC cells by regulating HIF-1α-dependent glycolysis through inactivation of the PI3K/Akt/mTOR pathway.
    Gong T, Cui L, Wang H, Wang H, Han N.
    J Transl Med; 2018 Jun 14; 16(1):164. PubMed ID: 29898734
    [Abstract] [Full Text] [Related]

  • 9. Polyphyllin VI, a saponin from Trillium tschonoskii Maxim. induces apoptotic and autophagic cell death via the ROS triggered mTOR signaling pathway in non-small cell lung cancer.
    Teng JF, Qin DL, Mei QB, Qiu WQ, Pan R, Xiong R, Zhao Y, Law BY, Wong VK, Tang Y, Yu CL, Zhang F, Wu JM, Wu AG.
    Pharmacol Res; 2019 Sep 14; 147():104396. PubMed ID: 31404628
    [Abstract] [Full Text] [Related]

  • 10. Polyphyllin II Restores Sensitization of the Resistance of PC-9/ZD Cells to Gefitinib by a Negative Regulation of the PI3K/Akt/mTOR Signaling Pathway.
    Zheng R, Jiang H, Li J, Liu X, Xu H.
    Curr Cancer Drug Targets; 2017 Sep 14; 17(4):376-385. PubMed ID: 28093061
    [Abstract] [Full Text] [Related]

  • 11. TAZ inhibition restores sensitivity of cisplatin via AKT/mTOR signaling in lung adenocarcinoma.
    Xu W, Wei Y, Li Y, Yin Y, Yuan W, Yang Y, Zhao W, Wu J.
    Oncol Rep; 2017 Sep 14; 38(3):1815-1821. PubMed ID: 28737828
    [Abstract] [Full Text] [Related]

  • 12. Polyphyllin I activates AMPK to suppress the growth of non-small-cell lung cancer via induction of autophagy.
    Wu Y, Si Y, Xiang Y, Zhou T, Liu X, Wu M, Li W, Zhang T, Xiang K, Zhang L, Zhao H, Liu Y.
    Arch Biochem Biophys; 2020 Jul 15; 687():108285. PubMed ID: 32074500
    [Abstract] [Full Text] [Related]

  • 13. Salvianolic acid A reverses cisplatin resistance in lung cancer A549 cells by targeting c-met and attenuating Akt/mTOR pathway.
    Tang XL, Yan L, Zhu L, Jiao DM, Chen J, Chen QY.
    J Pharmacol Sci; 2017 Sep 15; 135(1):1-7. PubMed ID: 28939129
    [Abstract] [Full Text] [Related]

  • 14. Bisdemethoxycurcumin sensitizes cisplatin-resistant lung cancer cells to chemotherapy by inhibition of CA916798 and PI3K/AKT signaling.
    Wang HJ, Yang ZX, Dai XT, Chen YF, Yang HP, Zhou XD.
    Apoptosis; 2017 Sep 15; 22(9):1157-1168. PubMed ID: 28677094
    [Abstract] [Full Text] [Related]

  • 15. miR-181 regulates cisplatin-resistant non-small cell lung cancer via downregulation of autophagy through the PTEN/PI3K/AKT pathway.
    Liu J, Xing Y, Rong L.
    Oncol Rep; 2018 Apr 15; 39(4):1631-1639. PubMed ID: 29484437
    [Abstract] [Full Text] [Related]

  • 16. Silencing long non-coding RNA ROR improves sensitivity of non-small-cell lung cancer to cisplatin resistance by inhibiting PI3K/Akt/mTOR signaling pathway.
    Shi H, Pu J, Zhou XL, Ning YY, Bai C.
    Tumour Biol; 2017 May 15; 39(5):1010428317697568. PubMed ID: 28459375
    [Abstract] [Full Text] [Related]

  • 17. [Ethoxysanguinarine directly targets CIP2A to inhibit proliferation and induce autophagy of SGC7901/DDP cells].
    Wan F, Tan M, Xiang YC, Liu XW, Peng P, Liu Y.
    Zhongguo Zhong Yao Za Zhi; 2022 Nov 15; 47(21):5890-5899. PubMed ID: 36472008
    [Abstract] [Full Text] [Related]

  • 18. Polyphyllin I Overcomes EMT-Associated Resistance to Erlotinib in Lung Cancer Cells via IL-6/STAT3 Pathway Inhibition.
    Lou W, Chen Y, Zhu KY, Deng H, Wu T, Wang J.
    Biol Pharm Bull; 2017 Aug 01; 40(8):1306-1313. PubMed ID: 28515374
    [Abstract] [Full Text] [Related]

  • 19. Polyphyllin I induces autophagy and cell cycle arrest via inhibiting PDK1/Akt/mTOR signal and downregulating cyclin B1 in human gastric carcinoma HGC-27 cells.
    He J, Yu S, Guo C, Tan L, Song X, Wang M, Wu J, Long Y, Gong D, Zhang R, Cao Z, Li Y, Peng C.
    Biomed Pharmacother; 2019 Sep 01; 117():109189. PubMed ID: 31387191
    [Abstract] [Full Text] [Related]

  • 20. Polyphyllin I induces apoptosis and autophagy via modulating JNK and mTOR pathways in human acute myeloid leukemia cells.
    Tian Y, Jia SX, Shi J, Gong GY, Yu JW, Niu Y, Yang CM, Ma XC, Fang MY.
    Chem Biol Interact; 2019 Sep 25; 311():108793. PubMed ID: 31421117
    [Abstract] [Full Text] [Related]

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