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Journal Abstract Search


573 related items for PubMed ID: 31707632

  • 1. The N-Terminal Polybasic Region of Prion Protein Is Crucial in Prion Pathogenesis Independently of the Octapeptide Repeat Region.
    Das NR, Miyata H, Hara H, Chida J, Uchiyama K, Masujin K, Watanabe H, Kondoh G, Sakaguchi S.
    Mol Neurobiol; 2020 Feb; 57(2):1203-1216. PubMed ID: 31707632
    [Abstract] [Full Text] [Related]

  • 2. Prion Protein Devoid of the Octapeptide Repeat Region Delays Bovine Spongiform Encephalopathy Pathogenesis in Mice.
    Hara H, Miyata H, Das NR, Chida J, Yoshimochi T, Uchiyama K, Watanabe H, Kondoh G, Yokoyama T, Sakaguchi S.
    J Virol; 2018 Jan 01; 92(1):. PubMed ID: 29046443
    [Abstract] [Full Text] [Related]

  • 3. Effects of prion protein devoid of the N-terminal residues 25-50 on prion pathogenesis in mice.
    Das NR, Miyata H, Hara H, Uchiyama K, Chida J, Yano M, Watanabe H, Kondoh G, Sakaguchi S.
    Arch Virol; 2017 Jul 01; 162(7):1867-1876. PubMed ID: 28255815
    [Abstract] [Full Text] [Related]

  • 4. Strain-Dependent Prion Infection in Mice Expressing Prion Protein with Deletion of Central Residues 91-106.
    Uchiyama K, Miyata H, Yamaguchi Y, Imamura M, Okazaki M, Pasiana AD, Chida J, Hara H, Atarashi R, Watanabe H, Kondoh G, Sakaguchi S.
    Int J Mol Sci; 2020 Oct 01; 21(19):. PubMed ID: 33019549
    [Abstract] [Full Text] [Related]

  • 5. Mouse-hamster chimeric prion protein (PrP) devoid of N-terminal residues 23-88 restores susceptibility to 22L prions, but not to RML prions in PrP-knockout mice.
    Uchiyama K, Miyata H, Yano M, Yamaguchi Y, Imamura M, Muramatsu N, Das NR, Chida J, Hara H, Sakaguchi S.
    PLoS One; 2014 Oct 01; 9(10):e109737. PubMed ID: 25330286
    [Abstract] [Full Text] [Related]

  • 6. Central residues in prion protein PrPC are crucial for its conversion into the pathogenic isoform.
    Pasiana AD, Miyata H, Chida J, Hara H, Imamura M, Atarashi R, Sakaguchi S.
    J Biol Chem; 2022 Sep 01; 298(9):102381. PubMed ID: 35973512
    [Abstract] [Full Text] [Related]

  • 7. N-Terminal Regions of Prion Protein: Functions and Roles in Prion Diseases.
    Hara H, Sakaguchi S.
    Int J Mol Sci; 2020 Aug 28; 21(17):. PubMed ID: 32872280
    [Abstract] [Full Text] [Related]

  • 8. Biological and biochemical characterization of mice expressing prion protein devoid of the octapeptide repeat region after infection with prions.
    Yamaguchi Y, Miyata H, Uchiyama K, Ootsuyama A, Inubushi S, Mori T, Muramatsu N, Katamine S, Sakaguchi S.
    PLoS One; 2012 Aug 28; 7(8):e43540. PubMed ID: 22927985
    [Abstract] [Full Text] [Related]

  • 9. Strain-dependent role of copper in prion disease through binding to histidine residues in the N-terminal domain of prion protein.
    Hara H, Miyata H, Chida J, Sakaguchi S.
    J Neurochem; 2023 Nov 28; 167(3):394-409. PubMed ID: 37777338
    [Abstract] [Full Text] [Related]

  • 10. Mutated but Not Deleted Ovine PrP(C) N-Terminal Polybasic Region Strongly Interferes with Prion Propagation in Transgenic Mice.
    Khalifé M, Reine F, Paquet-Fifield S, Castille J, Herzog L, Vilotte M, Moudjou M, Moazami-Goudarzi K, Makhzami S, Passet B, Andréoletti O, Vilette D, Laude H, Béringue V, Vilotte JL.
    J Virol; 2016 Feb 01; 90(3):1638-46. PubMed ID: 26608316
    [Abstract] [Full Text] [Related]

  • 11. The first non-prion pathogen identified: neurotropic influenza virus.
    Sakaguchi S, Hara H.
    Prion; 2022 Dec 01; 16(1):1-6. PubMed ID: 34978525
    [Abstract] [Full Text] [Related]

  • 12. The protease-sensitive N-terminal polybasic region of prion protein modulates its conversion to the pathogenic prion conformer.
    Zhang X, Pan YH, Chen Y, Pan C, Ma J, Yuan C, Yu G, Ma J.
    J Biol Chem; 2021 Nov 01; 297(5):101344. PubMed ID: 34710372
    [Abstract] [Full Text] [Related]

  • 13. Dissociation of infectivity from seeding ability in prions with alternate docking mechanism.
    Miller MB, Geoghegan JC, Supattapone S.
    PLoS Pathog; 2011 Jul 01; 7(7):e1002128. PubMed ID: 21779169
    [Abstract] [Full Text] [Related]

  • 14. Prion protein protects mice from lethal infection with influenza A viruses.
    Chida J, Hara H, Yano M, Uchiyama K, Das NR, Takahashi E, Miyata H, Tomioka Y, Ito T, Kido H, Sakaguchi S.
    PLoS Pathog; 2018 May 01; 14(5):e1007049. PubMed ID: 29723291
    [Abstract] [Full Text] [Related]

  • 15. Pathogenic mutations within the hydrophobic domain of the prion protein lead to the formation of protease-sensitive prion species with increased lethality.
    Coleman BM, Harrison CF, Guo B, Masters CL, Barnham KJ, Lawson VA, Hill AF.
    J Virol; 2014 Mar 01; 88(5):2690-703. PubMed ID: 24352465
    [Abstract] [Full Text] [Related]

  • 16. The prion gene complex encoding PrP(C) and Doppel: insights from mutational analysis.
    Mastrangelo P, Westaway D.
    Gene; 2001 Sep 05; 275(1):1-18. PubMed ID: 11574147
    [Abstract] [Full Text] [Related]

  • 17. Virus Infection, Genetic Mutations, and Prion Infection in Prion Protein Conversion.
    Hara H, Sakaguchi S.
    Int J Mol Sci; 2021 Nov 18; 22(22):. PubMed ID: 34830321
    [Abstract] [Full Text] [Related]

  • 18. Generating Bona Fide Mammalian Prions with Internal Deletions.
    Munoz-Montesino C, Sizun C, Moudjou M, Herzog L, Reine F, Chapuis J, Ciric D, Igel-Egalon A, Laude H, Béringue V, Rezaei H, Dron M.
    J Virol; 2016 Aug 01; 90(15):6963-6975. PubMed ID: 27226369
    [Abstract] [Full Text] [Related]

  • 19. The N-terminal, polybasic region of PrP(C) dictates the efficiency of prion propagation by binding to PrP(Sc).
    Turnbaugh JA, Unterberger U, Saá P, Massignan T, Fluharty BR, Bowman FP, Miller MB, Supattapone S, Biasini E, Harris DA.
    J Neurosci; 2012 Jun 27; 32(26):8817-30. PubMed ID: 22745483
    [Abstract] [Full Text] [Related]

  • 20. Novel amplification mechanism of prions through disrupting sortilin-mediated trafficking.
    Sakaguchi S, Uchiyama K.
    Prion; 2017 Nov 02; 11(6):398-404. PubMed ID: 29099278
    [Abstract] [Full Text] [Related]


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