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Journal Abstract Search

121 related items for PubMed ID: 3172130

  • 1. Structure-activity analysis of a class of orally active hydroxamic acid inhibitors of leukotriene biosynthesis.
    Summers JB, Gunn BP, Martin JG, Martin MB, Mazdiyasni H, Stewart AO, Young PR, Bouska JB, Goetze AM, Dyer RD.
    J Med Chem; 1988 Oct; 31(10):1960-4. PubMed ID: 3172130
    [Abstract] [Full Text] [Related]

  • 2. In vivo characterization of hydroxamic acid inhibitors of 5-lipoxygenase.
    Summers JB, Gunn BP, Mazdiyasni H, Goetze AM, Young PR, Bouska JB, Dyer RD, Brooks DW, Carter GW.
    J Med Chem; 1987 Nov; 30(11):2121-6. PubMed ID: 3669019
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and structure-activity relationships of novel 5-(hydroxamic acid)methyl oxazolidinone derivatives as 5-lipoxygenase inhibitors.
    Phillips OA, Bosso MA, Ezeamuzie CI.
    J Enzyme Inhib Med Chem; 2020 Dec; 35(1):1471-1482. PubMed ID: 32635785
    [Abstract] [Full Text] [Related]

  • 4. Hydroxamic acid inhibitors of 5-lipoxygenase: quantitative structure-activity relationships.
    Summers JB, Kim KH, Mazdiyasni H, Holms JH, Ratajczyk JD, Stewart AO, Dyer RD, Carter GW.
    J Med Chem; 1990 Mar; 33(3):992-8. PubMed ID: 2308149
    [Abstract] [Full Text] [Related]

  • 5. Hydroxamic acid inhibitors of 5-lipoxygenase.
    Summers JB, Mazdiyasni H, Holms JH, Ratajczyk JD, Dyer RD, Carter GW.
    J Med Chem; 1987 Mar; 30(3):574-80. PubMed ID: 3820229
    [Abstract] [Full Text] [Related]

  • 6. Antioxidant and anti-inflammatory activity of aryl-acetic and hydroxamic acids as novel lipoxygenase inhibitors.
    Pontiki E, Hadjipavlou-Litina D.
    Med Chem; 2006 May; 2(3):251-64. PubMed ID: 16948471
    [Abstract] [Full Text] [Related]

  • 7. New Hydroxycinnamic Acid Esters as Novel 5-Lipoxygenase Inhibitors That Affect Leukotriene Biosynthesis.
    Boudreau LH, Lassalle-Claux G, Cormier M, Blanchard S, Doucet MS, Surette ME, Touaibia M.
    Mediators Inflamm; 2017 May; 2017():6904634. PubMed ID: 28680195
    [Abstract] [Full Text] [Related]

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  • 10. Differential effects of a series of hydroxamic acid derivatives on 5-lipoxygenase and cyclooxygenase from neutrophils and 12-lipoxygenase from platelets and their in vivo effects on inflammation and anaphylaxis.
    Huang FC, Shoupe TS, Lin CJ, Lee TD, Chan WK, Tan J, Schnapper M, Suh JT, Gordon RJ, Sonnino PA.
    J Med Chem; 1989 Aug; 32(8):1836-42. PubMed ID: 2502629
    [Abstract] [Full Text] [Related]

  • 11. 5-Lipoxygenase: a target for antiinflammatory drugs revisited.
    Steinhilber D.
    Curr Med Chem; 1999 Jan; 6(1):71-85. PubMed ID: 9873115
    [Abstract] [Full Text] [Related]

  • 12. Substituted chromenes as potent, orally active 5-lipoxygenase inhibitors.
    Satoh Y, Stanton JL, Hutchison AJ, Libby AH, Kowalski TJ, Lee WH, White DH, Kimble EF.
    J Med Chem; 1993 Nov 12; 36(23):3580-94. PubMed ID: 8246226
    [Abstract] [Full Text] [Related]

  • 13. The effects of a novel series of selective inhibitors of arachidonate 5-lipoxygenase on anaphylactic and inflammatory responses.
    Bhattacherjee P, Boughton-Smith NK, Follenfant RL, Garland LG, Higgs GA, Hodson HF, Islip PJ, Jackson WP, Moncada S, Payne AN.
    Ann N Y Acad Sci; 1988 Nov 12; 524():307-20. PubMed ID: 2837965
    [Abstract] [Full Text] [Related]

  • 14. Acetohydroxamic acids as potent, selective, orally active 5-lipoxygenase inhibitors.
    Jackson WP, Islip PJ, Kneen G, Pugh A, Wates PJ.
    J Med Chem; 1988 Mar 12; 31(3):499-500. PubMed ID: 3346867
    [No Abstract] [Full Text] [Related]

  • 15. A test system for leukotriene synthesis inhibitors based on the in-vitro differentiation of the human leukemic cell lines HL-60 and Mono Mac 6.
    Werz O, Schneider N, Brungs M, Sailer ER, Safayhi H, Ammon HP, Steinhilber D.
    Naunyn Schmiedebergs Arch Pharmacol; 1997 Oct 12; 356(4):441-5. PubMed ID: 9349629
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of 5-lipoxygenase: development of hydroxamic acids and hydroxyureas as potential therapeutic agents.
    Salmon JA, Jackson WP, Garland LG.
    Adv Prostaglandin Thromboxane Leukot Res; 1991 Oct 12; 21A():109-12. PubMed ID: 1847758
    [No Abstract] [Full Text] [Related]

  • 17. Synthesis and biological evaluation of C(5)-substituted derivatives of leukotriene biosynthesis inhibitor BRP-7.
    Levent S, Gerstmeier J, Olgaç A, Nikels F, Garscha U, Carotti A, Macchiarulo A, Werz O, Banoglu E, Çalışkan B.
    Eur J Med Chem; 2016 Oct 21; 122():510-519. PubMed ID: 27423639
    [Abstract] [Full Text] [Related]

  • 18. Selective inhibition of arachidonate 5-lipoxygenase by novel acetohydroxamic acids: biochemical assessment in vitro and ex vivo.
    Tateson JE, Randall RW, Reynolds CH, Jackson WP, Bhattacherjee P, Salmon JA, Garland LG.
    Br J Pharmacol; 1988 Jun 21; 94(2):528-39. PubMed ID: 2840160
    [Abstract] [Full Text] [Related]

  • 19. Novel bishydroxamic acids as 5-lipoxygenase inhibitors.
    Ohemeng KA, Nguyen VN, Schwender CF, Singer M, Steber M, Ansell J, Hageman W.
    Bioorg Med Chem; 1994 Mar 21; 2(3):187-93. PubMed ID: 7922131
    [Abstract] [Full Text] [Related]

  • 20. Dibenzoxepinone hydroxylamines and hydroxamic acids: dual inhibitors of cyclooxygenase and 5-lipoxygenase with potent topical antiinflammatory activity.
    Hamer RR, Tegeler JJ, Kurtz ES, Allen RC, Bailey SC, Elliott ME, Hellyer L, Helsley GC, Przekop P, Freed BS, White J, Martin LL.
    J Med Chem; 1996 Jan 05; 39(1):246-52. PubMed ID: 8568814
    [Abstract] [Full Text] [Related]

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