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Journal Abstract Search

121 related items for PubMed ID: 31734023

  • 1. Preliminary SAR and biological evaluation of potent HIV-1 protease inhibitors with pyrimidine bases as novel P2 ligands to enhance activity against DRV-resistant HIV-1 variants.
    Zhu M, Ma L, Zhou H, Dong B, Wang Y, Wang Z, Zhou J, Zhang G, Wang J, Liang C, Cen S, Wang Y.
    Eur J Med Chem; 2020 Jan 01; 185():111866. PubMed ID: 31734023
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  • 2. Design and synthesis of potent HIV-1 protease inhibitors with (S)-tetrahydrofuran-tertiary amine-acetamide as P2-ligand: Structure-activity studies and biological evaluation.
    Bai X, Yang Z, Zhu M, Dong B, Zhou L, Zhang G, Wang J, Wang Y.
    Eur J Med Chem; 2017 Sep 08; 137():30-44. PubMed ID: 28554091
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  • 3. Design and evaluation of novel piperidine HIV-1 protease inhibitors with potency against DRV-resistant variants.
    Zhu M, Zhou H, Ma L, Dong B, Zhou J, Zhang G, Wang M, Wang J, Cen S, Wang Y.
    Eur J Med Chem; 2021 Aug 05; 220():113450. PubMed ID: 33906049
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  • 6. Synthesis and biological evaluation of novel HIV-1 protease inhibitors using tertiary amine as P2-ligands.
    Yang ZH, Bai XG, Zhou L, Wang JX, Liu HT, Wang YC.
    Bioorg Med Chem Lett; 2015 May 01; 25(9):1880-3. PubMed ID: 25838144
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  • 10. Rational design, synthesis and biological evaluation of novel HIV-1 protease inhibitors containing 2-phenylacetamide derivatives as P2 ligands with potent activity against DRV-Resistant HIV-1 variants.
    Meng S, Gao Y, Qiang G, Hu Z, Shan Q, Wang J, Wang Y, Mou J.
    Bioorg Med Chem Lett; 2024 Mar 15; 101():129651. PubMed ID: 38342391
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  • 11. Synthesis and biological evaluation of new HIV-1 protease inhibitors with purine bases as P2-ligands.
    Zhu M, Dong B, Zhang GN, Wang JX, Cen S, Wang YC.
    Bioorg Med Chem Lett; 2019 Jun 15; 29(12):1541-1545. PubMed ID: 31014912
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  • 14. Piperidine scaffold as the novel P2-ligands in cyclopropyl-containing HIV-1 protease inhibitors: Structure-based design, synthesis, biological evaluation and docking study.
    Zhou H, Zhu M, Ma L, Zhou J, Dong B, Zhang G, Cen S, Wang Y, Wang J.
    PLoS One; 2020 Jun 15; 15(7):e0235483. PubMed ID: 32697773
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  • 16. Structure-Based Design of Highly Potent HIV-1 Protease Inhibitors Containing New Tricyclic Ring P2-Ligands: Design, Synthesis, Biological, and X-ray Structural Studies.
    Ghosh AK, Kovela S, Osswald HL, Amano M, Aoki M, Agniswamy J, Wang YF, Weber IT, Mitsuya H.
    J Med Chem; 2020 May 14; 63(9):4867-4879. PubMed ID: 32348139
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  • 18. Arylazolyl(azinyl)thioacetanilides. Part 16: Structure-based bioisosterism design, synthesis and biological evaluation of novel pyrimidinylthioacetanilides as potent HIV-1 inhibitors.
    Li X, Lu X, Chen W, Liu H, Zhan P, Pannecouque C, Balzarini J, De Clercq E, Liu X.
    Bioorg Med Chem; 2014 Oct 01; 22(19):5290-7. PubMed ID: 25150090
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  • 19. Design, synthesis, X-ray studies, and biological evaluation of novel macrocyclic HIV-1 protease inhibitors involving the P1'-P2' ligands.
    Ghosh AK, Sean Fyvie W, Brindisi M, Steffey M, Agniswamy J, Wang YF, Aoki M, Amano M, Weber IT, Mitsuya H.
    Bioorg Med Chem Lett; 2017 Nov 01; 27(21):4925-4931. PubMed ID: 28958624
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