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528 related items for PubMed ID: 31735356

  • 1. Conjugates of tacrine and 1,2,4-thiadiazole derivatives as new potential multifunctional agents for Alzheimer's disease treatment: Synthesis, quantum-chemical characterization, molecular docking, and biological evaluation.
    Makhaeva GF, Kovaleva NV, Boltneva NP, Lushchekina SV, Rudakova EV, Stupina TS, Terentiev AA, Serkov IV, Proshin AN, Radchenko EV, Palyulin VA, Bachurin SO, Richardson RJ.
    Bioorg Chem; 2020 Jan; 94():103387. PubMed ID: 31735356
    [Abstract] [Full Text] [Related]

  • 2. Amiridine-piperazine hybrids as cholinesterase inhibitors and potential multitarget agents for Alzheimer's disease treatment.
    Makhaeva GF, Lushchekina SV, Kovaleva NV, Yu Astakhova T, Boltneva NP, Rudakova EV, Serebryakova OG, Proshin AN, Serkov IV, Trofimova TP, Tafeenko VA, Radchenko EV, Palyulin VA, Fisenko VP, Korábečný J, Soukup O, Richardson RJ.
    Bioorg Chem; 2021 Jul; 112():104974. PubMed ID: 34029971
    [Abstract] [Full Text] [Related]

  • 3. Conjugates of Tacrine and Salicylic Acid Derivatives as New Promising Multitarget Agents for Alzheimer's Disease.
    Makhaeva GF, Kovaleva NV, Rudakova EV, Boltneva NP, Grishchenko MV, Lushchekina SV, Astakhova TY, Serebryakova OG, Timokhina EN, Zhilina EF, Shchegolkov EV, Ulitko MV, Radchenko EV, Palyulin VA, Burgart YV, Saloutin VI, Bachurin SO, Richardson RJ.
    Int J Mol Sci; 2023 Jan 24; 24(3):. PubMed ID: 36768608
    [Abstract] [Full Text] [Related]

  • 4. Bis-Amiridines as Acetylcholinesterase and Butyrylcholinesterase Inhibitors: N-Functionalization Determines the Multitarget Anti-Alzheimer's Activity Profile.
    Makhaeva GF, Kovaleva NV, Boltneva NP, Rudakova EV, Lushchekina SV, Astakhova TY, Serkov IV, Proshin AN, Radchenko EV, Palyulin VA, Korabecny J, Soukup O, Bachurin SO, Richardson RJ.
    Molecules; 2022 Feb 04; 27(3):. PubMed ID: 35164325
    [Abstract] [Full Text] [Related]

  • 5. Conjugates of Tacrine with Salicylamide as Promising Multitarget Agents for Alzheimer's Disease.
    Grishchenko MV, Makhaeva GF, Burgart YV, Rudakova EV, Boltneva NP, Kovaleva NV, Serebryakova OG, Lushchekina SV, Astakhova TY, Zhilina EF, Shchegolkov EV, Richardson RJ, Saloutin VI.
    ChemMedChem; 2022 May 18; 17(10):e202200080. PubMed ID: 35322571
    [Abstract] [Full Text] [Related]

  • 6. Design, Synthesis, and Molecular Docking of Some Novel Tacrine Based Cyclopentapyranopyridine- and Tetrahydropyranoquinoline-Kojic Acid Derivatives as Anti-Acetylcholinesterase Agents.
    Babaee S, Chehardoli G, Akbarzadeh T, Zolfigol MA, Mahdavi M, Rastegari A, Homayouni Moghadam F, Najafi Z.
    Chem Biodivers; 2021 Jun 18; 18(6):e2000924. PubMed ID: 33861892
    [Abstract] [Full Text] [Related]

  • 7. New Multifunctional Agents for Potential Alzheimer's Disease Treatment Based on Tacrine Conjugates with 2-Arylhydrazinylidene-1,3-Diketones.
    Elkina NA, Grishchenko MV, Shchegolkov EV, Makhaeva GF, Kovaleva NV, Rudakova EV, Boltneva NP, Lushchekina SV, Astakhova TY, Radchenko EV, Palyulin VA, Zhilina EF, Perminova AN, Lapshin LS, Burgart YV, Saloutin VI, Richardson RJ.
    Biomolecules; 2022 Oct 24; 12(11):. PubMed ID: 36358901
    [Abstract] [Full Text] [Related]

  • 8. New Hybrids of 4-Amino-2,3-polymethylene-quinoline and p-Tolylsulfonamide as Dual Inhibitors of Acetyl- and Butyrylcholinesterase and Potential Multifunctional Agents for Alzheimer's Disease Treatment.
    Makhaeva GF, Kovaleva NV, Boltneva NP, Lushchekina SV, Astakhova TY, Rudakova EV, Proshin AN, Serkov IV, Radchenko EV, Palyulin VA, Bachurin SO, Richardson RJ.
    Molecules; 2020 Aug 27; 25(17):. PubMed ID: 32867324
    [Abstract] [Full Text] [Related]

  • 9. Synthesis, biological evaluation and molecular modeling study of novel tacrine-carbazole hybrids as potential multifunctional agents for the treatment of Alzheimer's disease.
    Thiratmatrakul S, Yenjai C, Waiwut P, Vajragupta O, Reubroycharoen P, Tohda M, Boonyarat C.
    Eur J Med Chem; 2014 Mar 21; 75():21-30. PubMed ID: 24508831
    [Abstract] [Full Text] [Related]

  • 10. Design, synthesis and biological activity of novel tacrine-isatin Schiff base hybrid derivatives.
    Riazimontazer E, Sadeghpour H, Nadri H, Sakhteman A, Tüylü Küçükkılınç T, Miri R, Edraki N.
    Bioorg Chem; 2019 Aug 21; 89():103006. PubMed ID: 31158577
    [Abstract] [Full Text] [Related]

  • 11. Design, synthesis and evaluation of novel tacrine-(β-carboline) hybrids as multifunctional agents for the treatment of Alzheimer's disease.
    Lan JS, Xie SS, Li SY, Pan LF, Wang XB, Kong LY.
    Bioorg Med Chem; 2014 Nov 01; 22(21):6089-104. PubMed ID: 25282654
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and Biological Activity of Some Benzochromenoquinolinones: Tacrine Analogs as Potent Anti-Alzheimer's Agents.
    Mahdavi M, Hariri R, Mirfazli SS, Lotfian H, Rastergari A, Firuzi O, Edraki N, Larijani B, Akbarzadeh T, Saeedi M.
    Chem Biodivers; 2019 Apr 01; 16(4):e1800488. PubMed ID: 30720917
    [Abstract] [Full Text] [Related]

  • 13. Synthesis, bioactivity and molecular modeling studies on potential anti-Alzheimer piperidinehydrazide-hydrazones.
    Parlar S, Sayar G, Tarikogullari AH, Karadagli SS, Alptuzun V, Erciyas E, Holzgrabe U.
    Bioorg Chem; 2019 Jun 01; 87():888-900. PubMed ID: 30538051
    [Abstract] [Full Text] [Related]

  • 14. 9-Substituted acridine derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors possessing antioxidant activity for Alzheimer's disease treatment.
    Makhaeva GF, Lushchekina SV, Boltneva NP, Serebryakova OG, Rudakova EV, Ustyugov AA, Bachurin SO, Shchepochkin AV, Chupakhin ON, Charushin VN, Richardson RJ.
    Bioorg Med Chem; 2017 Nov 01; 25(21):5981-5994. PubMed ID: 28986116
    [Abstract] [Full Text] [Related]

  • 15. Novel tacrine-8-hydroxyquinoline hybrids as multifunctional agents for the treatment of Alzheimer's disease, with neuroprotective, cholinergic, antioxidant, and copper-complexing properties.
    Fernández-Bachiller MI, Pérez C, González-Muñoz GC, Conde S, López MG, Villarroya M, García AG, Rodríguez-Franco MI.
    J Med Chem; 2010 Jul 08; 53(13):4927-37. PubMed ID: 20545360
    [Abstract] [Full Text] [Related]

  • 16. Further SAR studies on natural template based neuroprotective molecules for the treatment of Alzheimer's disease.
    Singh YP, Shankar G, Jahan S, Singh G, Kumar N, Barik A, Upadhyay P, Singh L, Kamble K, Singh GK, Tiwari S, Garg P, Gupta S, Modi G.
    Bioorg Med Chem; 2021 Sep 15; 46():116385. PubMed ID: 34481338
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis and pharmacological evaluation of novel tacrine-caffeic acid hybrids as multi-targeted compounds against Alzheimer's disease.
    Chao X, He X, Yang Y, Zhou X, Jin M, Liu S, Cheng Z, Liu P, Wang Y, Yu J, Tan Y, Huang Y, Qin J, Rapposelli S, Pi R.
    Bioorg Med Chem Lett; 2012 Oct 15; 22(20):6498-502. PubMed ID: 22981331
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis and neuroprotective evaluation of novel tacrine-benzothiazole hybrids as multi-targeted compounds against Alzheimer's disease.
    Keri RS, Quintanova C, Marques SM, Esteves AR, Cardoso SM, Santos MA.
    Bioorg Med Chem; 2013 Aug 01; 21(15):4559-69. PubMed ID: 23768661
    [Abstract] [Full Text] [Related]

  • 19. Tacrine-hydroxamate derivatives as multitarget-directed ligands for the treatment of Alzheimer's disease: Design, synthesis, and biological evaluation.
    Xu A, He F, Zhang X, Li X, Ran Y, Wei C, James Chou C, Zhang R, Wu J.
    Bioorg Chem; 2020 May 01; 98():103721. PubMed ID: 32193030
    [Abstract] [Full Text] [Related]

  • 20. Novel conjugates of tacrine with 1,2,4,-thiadiazole as highly effective cholinesterase inhibitors, blockers of NMDA receptors, and antioxidants.
    Makhaeva GF, Grigoriev VV, Proshin AN, Kovaleva NV, Rudakova EV, Boltneva NP, Serkov IV, Bachurin SO.
    Dokl Biochem Biophys; 2017 Nov 01; 477(1):405-409. PubMed ID: 29297118
    [Abstract] [Full Text] [Related]

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