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Journal Abstract Search

141 related items for PubMed ID: 31759826

  • 1. Development of novel phenoxy-diketopiperazine-type plinabulin derivatives as potent antimicrotubule agents based on the co-crystal structure.
    Ding Z, Ma M, Zhong C, Wang S, Fu Z, Hou Y, Liu Y, Zhong L, Chu Y, Li F, Song C, Wang Y, Yang J, Li W.
    Bioorg Med Chem; 2020 Jan 01; 28(1):115186. PubMed ID: 31759826
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis and biological evaluation of anti-pancreatic cancer activity of plinabulin derivatives based on the co-crystal structure.
    Fu Z, Hou Y, Ji C, Ma M, Tian Z, Deng M, Zhong L, Chu Y, Li W.
    Bioorg Med Chem; 2018 May 01; 26(8):2061-2072. PubMed ID: 29571653
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  • 3. Structure-based design and synthesis of novel furan-diketopiperazine-type derivatives as potent microtubule inhibitors for treating cancer.
    Ding Z, Li F, Zhong C, Li F, Liu Y, Wang S, Zhao J, Li W.
    Bioorg Med Chem; 2020 May 15; 28(10):115435. PubMed ID: 32278711
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and structure-activity relationship study of antimicrotubule agents phenylahistin derivatives with a didehydropiperazine-2,5-dione structure.
    Yamazaki Y, Tanaka K, Nicholson B, Deyanat-Yazdi G, Potts B, Yoshida T, Oda A, Kitagawa T, Orikasa S, Kiso Y, Yasui H, Akamatsu M, Chinen T, Usui T, Shinozaki Y, Yakushiji F, Miller BR, Neuteboom S, Palladino M, Kanoh K, Lloyd GK, Hayashi Y.
    J Med Chem; 2012 Feb 09; 55(3):1056-71. PubMed ID: 22185476
    [Abstract] [Full Text] [Related]

  • 5. Polymorphs, co-crystal structure and pharmacodynamics study of MBRI-001, a deuterium-substituted plinabulin derivative as a tubulin polymerization inhibitor.
    Ma M, Ding Z, Wang S, Ma L, Wang Y, Zhong L, Li Z, Yang J, Li W.
    Bioorg Med Chem; 2019 May 01; 27(9):1836-1844. PubMed ID: 30910474
    [Abstract] [Full Text] [Related]

  • 6. Design, Synthesis, In Vitro Anti-cancer Activity, ADMET Profile and Molecular Docking of Novel Triazolo[3,4-a]phthalazine Derivatives Targeting VEGFR-2 Enzyme.
    El-Helby AA, Sakr H, Ayyad RRA, El-Adl K, Ali MM, Khedr F.
    Anticancer Agents Med Chem; 2018 May 01; 18(8):1184-1196. PubMed ID: 29651967
    [Abstract] [Full Text] [Related]

  • 7. Design and Synthesis of Novel Phenylahistin Derivatives Based on Co-Crystal Structures as Potent Microtubule Inhibitors for Anti-Cancer Therapy.
    Ding Z, Li F, Xie L, Gu M, Li C, Liu C, Peng C, Li W.
    Mar Drugs; 2022 Nov 29; 20(12):. PubMed ID: 36547899
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis, and structure-activity relationship study of novel plinabulin derivatives as anti-tumor agents based on the co-crystal structure.
    Wang S, Zhong C, Li F, Ding Z, Tang Y, Li W.
    Mol Divers; 2024 Apr 23. PubMed ID: 38652366
    [Abstract] [Full Text] [Related]

  • 9. Medicinal chemistry and chemical biology of diketopiperazine-type antimicrotubule and vascular-disrupting agents.
    Hayashi Y, Yamazaki-Nakamura Y, Yakushiji F.
    Chem Pharm Bull (Tokyo); 2013 Apr 23; 61(9):889-901. PubMed ID: 23995353
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  • 13. Discovery of 1,3-Disubstituted 2,5-Diketopiperazine Derivatives as Potent Class I HDACs Inhibitors.
    Gong G, Qi J, Lv Y, Dong S, Cao C, Li D, Zhao R, Li Z, Chen X.
    Chem Pharm Bull (Tokyo); 2020 Apr 23; 68(5):466-472. PubMed ID: 32378544
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and activity evaluation of the cyclic dipeptides arylidene N-alkoxydiketopiperazines.
    Tian X, Feng J, Fan SM, Zhen XL, Han JR, Liu SX.
    Bioorg Med Chem; 2016 Nov 01; 24(21):5197-5205. PubMed ID: 27594550
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  • 15. Synthesis and structure-activity relationships of benzophenone-bearing diketopiperazine-type anti-microtubule agents.
    Yamazaki Y, Sumikura M, Masuda Y, Hayashi Y, Yasui H, Kiso Y, Chinen T, Usui T, Yakushiji F, Potts B, Neuteboom S, Palladino M, Lloyd GK, Hayashi Y.
    Bioorg Med Chem; 2012 Jul 15; 20(14):4279-89. PubMed ID: 22727370
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  • 16. Synthesis of deuterium-enriched and fluorine-substituted plinabulin derivatives and evaluation of their antitumor activities.
    Ding Z, Hou Y, Wang S, Sun T, Ma M, Guan H, Li W.
    Mol Divers; 2017 Aug 15; 21(3):577-583. PubMed ID: 28488201
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  • 19. Saroclazines A-C, thio-diketopiperazines from mangrove-derived fungi Sarocladium kiliense HDN11-84.
    Li F, Guo W, Wu L, Zhu T, Gu Q, Li D, Che Q.
    Arch Pharm Res; 2018 Jan 15; 41(1):30-34. PubMed ID: 29103141
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