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1436 related items for PubMed ID: 31760070

  • 1. Inhibition of receptor-interacting protein kinase 1 improves experimental non-alcoholic fatty liver disease.
    Majdi A, Aoudjehane L, Ratziu V, Islam T, Afonso MB, Conti F, Mestiri T, Lagouge M, Foufelle F, Ballenghien F, Ledent T, Moldes M, Cadoret A, Fouassier L, Delaunay JL, Aït-Slimane T, Courtois G, Fève B, Scatton O, Prip-Buus C, Rodrigues CMP, Housset C, Gautheron J.
    J Hepatol; 2020 Apr; 72(4):627-635. PubMed ID: 31760070
    [Abstract] [Full Text] [Related]

  • 2. Decrease in fat de novo synthesis and chemokine ligand expression in non-alcoholic fatty liver disease caused by inhibition of mixed lineage kinase domain-like pseudokinase.
    Saeed WK, Jun DW, Jang K, Oh JH, Chae YJ, Lee JS, Koh DH, Kang HT.
    J Gastroenterol Hepatol; 2019 Dec; 34(12):2206-2218. PubMed ID: 31132314
    [Abstract] [Full Text] [Related]

  • 3. MLKL-dependent signaling regulates autophagic flux in a murine model of non-alcohol-associated fatty liver and steatohepatitis.
    Wu X, Poulsen KL, Sanz-Garcia C, Huang E, McMullen MR, Roychowdhury S, Dasarathy S, Nagy LE.
    J Hepatol; 2020 Sep; 73(3):616-627. PubMed ID: 32220583
    [Abstract] [Full Text] [Related]

  • 4. Necroptosis is a key pathogenic event in human and experimental murine models of non-alcoholic steatohepatitis.
    Afonso MB, Rodrigues PM, Carvalho T, Caridade M, Borralho P, Cortez-Pinto H, Castro RE, Rodrigues CM.
    Clin Sci (Lond); 2015 Oct 01; 129(8):721-39. PubMed ID: 26201023
    [Abstract] [Full Text] [Related]

  • 5. Mismatched effects of receptor interacting protein kinase-3 on hepatic steatosis and inflammation in non-alcoholic fatty liver disease.
    Saeed WK, Jun DW, Jang K, Ahn SB, Oh JH, Chae YJ, Lee JS, Kang HT.
    World J Gastroenterol; 2018 Dec 28; 24(48):5477-5490. PubMed ID: 30622377
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of keratinocyte necroptosis mediated by RIPK1/RIPK3/MLKL provides a protective effect against psoriatic inflammation.
    Duan X, Liu X, Liu N, Huang Y, Jin Z, Zhang S, Ming Z, Chen H.
    Cell Death Dis; 2020 Feb 19; 11(2):134. PubMed ID: 32075957
    [Abstract] [Full Text] [Related]

  • 7. Receptor-Interacting Serine/Threonine-Protein Kinase 3 (RIPK3)-Mixed Lineage Kinase Domain-Like Protein (MLKL)-Mediated Necroptosis Contributes to Ischemia-Reperfusion Injury of Steatotic Livers.
    Ni HM, Chao X, Kaseff J, Deng F, Wang S, Shi YH, Li T, Ding WX, Jaeschke H.
    Am J Pathol; 2019 Jul 19; 189(7):1363-1374. PubMed ID: 31026418
    [Abstract] [Full Text] [Related]

  • 8. The role of MLKL in Hepatic Ischemia-Reperfusion Injury of Alcoholic Steatotic Livers.
    Chen H, McKeen T, Chao X, Chen A, Deng F, Jaeschke H, Ding WX, Ni HM.
    Int J Biol Sci; 2022 Jul 19; 18(3):1096-1106. PubMed ID: 35173541
    [Abstract] [Full Text] [Related]

  • 9. Knockdown of RIPK1 Markedly Exacerbates Murine Immune-Mediated Liver Injury through Massive Apoptosis of Hepatocytes, Independent of Necroptosis and Inhibition of NF-κB.
    Suda J, Dara L, Yang L, Aghajan M, Song Y, Kaplowitz N, Liu ZX.
    J Immunol; 2016 Oct 15; 197(8):3120-3129. PubMed ID: 27605011
    [Abstract] [Full Text] [Related]

  • 10. RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury.
    Newton K, Dugger DL, Maltzman A, Greve JM, Hedehus M, Martin-McNulty B, Carano RA, Cao TC, van Bruggen N, Bernstein L, Lee WP, Wu X, DeVoss J, Zhang J, Jeet S, Peng I, McKenzie BS, Roose-Girma M, Caplazi P, Diehl L, Webster JD, Vucic D.
    Cell Death Differ; 2016 Sep 01; 23(9):1565-76. PubMed ID: 27177019
    [Abstract] [Full Text] [Related]

  • 11. Ligustroflavone reduces necroptosis in rat brain after ischemic stroke through targeting RIPK1/RIPK3/MLKL pathway.
    Zhang YY, Liu WN, Li YQ, Zhang XJ, Yang J, Luo XJ, Peng J.
    Naunyn Schmiedebergs Arch Pharmacol; 2019 Sep 01; 392(9):1085-1095. PubMed ID: 31055628
    [Abstract] [Full Text] [Related]

  • 12. Receptor-interacting protein kinase-1 ablation in liver parenchymal cells promotes liver fibrosis in murine NASH without affecting other symptoms.
    Farooq M, Simoes Eugénio M, Piquet-Pellorce C, Dion S, Raguenes-Nicol C, Santamaria K, Kara-Ali GH, Larcher T, Dimanche-Boitrel MT, Samson M, Le Seyec J.
    J Mol Med (Berl); 2022 Jul 01; 100(7):1027-1038. PubMed ID: 35476028
    [Abstract] [Full Text] [Related]

  • 13. TLR9 is up-regulated in human and murine NASH: pivotal role in inflammatory recruitment and cell survival.
    Mridha AR, Haczeyni F, Yeh MM, Haigh WG, Ioannou GN, Barn V, Ajamieh H, Adams L, Hamdorf JM, Teoh NC, Farrell GC.
    Clin Sci (Lond); 2017 Aug 15; 131(16):2145-2159. PubMed ID: 28687713
    [Abstract] [Full Text] [Related]

  • 14. Protein-Bound Polysaccharides from Coriolus Versicolor Induce RIPK1/RIPK3/MLKL-Mediated Necroptosis in ER-Positive Breast Cancer and Amelanotic Melanoma Cells.
    Pawlikowska M, Jędrzejewski T, Brożyna AA, Wrotek S.
    Cell Physiol Biochem; 2020 Jun 13; 54(4):591-604. PubMed ID: 32531147
    [Abstract] [Full Text] [Related]

  • 15. Caspase-8, receptor-interacting protein kinase 1 (RIPK1), and RIPK3 regulate retinoic acid-induced cell differentiation and necroptosis.
    Someda M, Kuroki S, Miyachi H, Tachibana M, Yonehara S.
    Cell Death Differ; 2020 May 13; 27(5):1539-1553. PubMed ID: 31659279
    [Abstract] [Full Text] [Related]

  • 16. Epigenetic Silencing of RIPK3 in Hepatocytes Prevents MLKL-mediated Necroptosis From Contributing to Liver Pathologies.
    Preston SP, Stutz MD, Allison CC, Nachbur U, Gouil Q, Tran BM, Duvivier V, Arandjelovic P, Cooney JP, Mackiewicz L, Meng Y, Schaefer J, Bader SM, Peng H, Valaydon Z, Rajasekaran P, Jennison C, Lopaticki S, Farrell A, Ryan M, Howell J, Croagh C, Karunakaran D, Schuster-Klein C, Murphy JM, Fifis T, Christophi C, Vincan E, Blewitt ME, Thompson A, Boddey JA, Doerflinger M, Pellegrini M.
    Gastroenterology; 2022 Dec 13; 163(6):1643-1657.e14. PubMed ID: 36037995
    [Abstract] [Full Text] [Related]

  • 17. The pseudokinase MLKL regulates hepatic insulin sensitivity independently of inflammation.
    Xu H, Du X, Liu G, Huang S, Du W, Zou S, Tang D, Fan C, Xie Y, Wei Y, Tian Y, Fu X.
    Mol Metab; 2019 May 13; 23():14-23. PubMed ID: 30837196
    [Abstract] [Full Text] [Related]

  • 18. The Lck inhibitor, AMG-47a, blocks necroptosis and implicates RIPK1 in signalling downstream of MLKL.
    Jacobsen AV, Pierotti CL, Lowes KN, Au AE, Zhang Y, Etemadi N, Fitzgibbon C, Kersten WJA, Samson AL, van Delft MF, Huang DCS, Sabroux HJ, Lessene G, Silke J, Murphy JM.
    Cell Death Dis; 2022 Apr 01; 13(4):291. PubMed ID: 35365636
    [Abstract] [Full Text] [Related]

  • 19. Identification of the Raf kinase inhibitor TAK-632 and its analogues as potent inhibitors of necroptosis by targeting RIPK1 and RIPK3.
    Chen X, Zhuang C, Ren Y, Zhang H, Qin X, Hu L, Fu J, Miao Z, Chai Y, Liu ZG, Zhang H, Cai Z, Wang HY.
    Br J Pharmacol; 2019 Jun 01; 176(12):2095-2108. PubMed ID: 30825190
    [Abstract] [Full Text] [Related]

  • 20. RIPK1/RIPK3/MLKL-mediated necroptosis contributes to compression-induced rat nucleus pulposus cells death.
    Chen S, Lv X, Hu B, Shao Z, Wang B, Ma K, Lin H, Cui M.
    Apoptosis; 2017 May 01; 22(5):626-638. PubMed ID: 28289909
    [Abstract] [Full Text] [Related]

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