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Journal Abstract Search


256 related items for PubMed ID: 31776202

  • 21. Changes in astrocyte shape induced by sublytic concentrations of the cholesterol-dependent cytolysin pneumolysin still require pore-forming capacity.
    Förtsch C, Hupp S, Ma J, Mitchell TJ, Maier E, Benz R, Iliev AI.
    Toxins (Basel); 2011 Jan; 3(1):43-62. PubMed ID: 22069689
    [Abstract] [Full Text] [Related]

  • 22. Circulating Pneumolysin Is a Potent Inducer of Cardiac Injury during Pneumococcal Infection.
    Alhamdi Y, Neill DR, Abrams ST, Malak HA, Yahya R, Barrett-Jolley R, Wang G, Kadioglu A, Toh CH.
    PLoS Pathog; 2015 May; 11(5):e1004836. PubMed ID: 25973949
    [Abstract] [Full Text] [Related]

  • 23. Pneumolysin activates macrophage lysosomal membrane permeabilization and executes apoptosis by distinct mechanisms without membrane pore formation.
    Bewley MA, Naughton M, Preston J, Mitchell A, Holmes A, Marriott HM, Read RC, Mitchell TJ, Whyte MK, Dockrell DH.
    mBio; 2014 Oct 07; 5(5):e01710-14. PubMed ID: 25293758
    [Abstract] [Full Text] [Related]

  • 24. The impact of pneumolysin on the macrophage response to Streptococcus pneumoniae is strain-dependent.
    Harvey RM, Hughes CE, Paton AW, Trappetti C, Tweten RK, Paton JC.
    PLoS One; 2014 Oct 07; 9(8):e103625. PubMed ID: 25105894
    [Abstract] [Full Text] [Related]

  • 25. Pneumolysin with low hemolytic activity confers an early growth advantage to Streptococcus pneumoniae in the blood.
    Harvey RM, Ogunniyi AD, Chen AY, Paton JC.
    Infect Immun; 2011 Oct 07; 79(10):4122-30. PubMed ID: 21788389
    [Abstract] [Full Text] [Related]

  • 26. Pneumolysin-Dependent Calpain Activation and Interleukin-1α Secretion in Macrophages Infected with Streptococcus pneumoniae.
    Fang R, Wu R, Du H, Jin M, Liu Y, Lei G, Jiang B, Lei Z, Peng Y, Nie K, Tsuchiya K.
    Infect Immun; 2017 Sep 07; 85(9):. PubMed ID: 28630064
    [Abstract] [Full Text] [Related]

  • 27. Streptococcus pneumoniae disrupts pulmonary immune defence via elastase release following pneumolysin-dependent neutrophil lysis.
    Domon H, Oda M, Maekawa T, Nagai K, Takeda W, Terao Y.
    Sci Rep; 2016 Nov 28; 6():38013. PubMed ID: 27892542
    [Abstract] [Full Text] [Related]

  • 28. Pneumolysin suppresses the initial macrophage pro-inflammatory response to Streptococcus pneumoniae.
    Periselneris J, Turner CT, Ercoli G, Szylar G, Weight CM, Thurston T, Whelan M, Tomlinson G, Noursadeghi M, Brown J.
    Immunology; 2022 Nov 28; 167(3):413-427. PubMed ID: 35835695
    [Abstract] [Full Text] [Related]

  • 29. Additive inhibition of complement deposition by pneumolysin and PspA facilitates Streptococcus pneumoniae septicemia.
    Yuste J, Botto M, Paton JC, Holden DW, Brown JS.
    J Immunol; 2005 Aug 01; 175(3):1813-9. PubMed ID: 16034123
    [Abstract] [Full Text] [Related]

  • 30. Designed reduction of Streptococcus pneumoniae pathogenicity via synthetic changes in virulence factor codon-pair bias.
    Coleman JR, Papamichail D, Yano M, García-Suárez Mdel M, Pirofski LA.
    J Infect Dis; 2011 May 01; 203(9):1264-73. PubMed ID: 21343143
    [Abstract] [Full Text] [Related]

  • 31. Inhibitory Effect of the Traditional Chinese Medicine Ephedra sinica granules on Streptococcus pneumoniae Pneumolysin.
    Xu Y, Wei L, Wang Y, Ding L, Guo Y, Sun X, Kong Y, Guo L, Guo T, Sun L.
    Biol Pharm Bull; 2020 May 01; 43(6):994-999. PubMed ID: 32475921
    [Abstract] [Full Text] [Related]

  • 32. Quercetin, a pneumolysin inhibitor, protects mice against Streptococcus pneumoniae infection.
    Lv Q, Zhang P, Quan P, Cui M, Liu T, Yin Y, Chi G.
    Microb Pathog; 2020 Mar 01; 140():103934. PubMed ID: 31862394
    [Abstract] [Full Text] [Related]

  • 33. Acacetin inhibits Streptococcus pneumoniae virulence by targeting pneumolysin.
    Li S, Lv Q, Sun X, Tang T, Deng X, Yin Y, Li L.
    J Pharm Pharmacol; 2020 Aug 01; 72(8):1092-1100. PubMed ID: 32390150
    [Abstract] [Full Text] [Related]

  • 34. Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4.
    McNeela EA, Burke A, Neill DR, Baxter C, Fernandes VE, Ferreira D, Smeaton S, El-Rachkidy R, McLoughlin RM, Mori A, Moran B, Fitzgerald KA, Tschopp J, Pétrilli V, Andrew PW, Kadioglu A, Lavelle EC.
    PLoS Pathog; 2010 Nov 11; 6(11):e1001191. PubMed ID: 21085613
    [Abstract] [Full Text] [Related]

  • 35. Peptidoglycan Branched Stem Peptides Contribute to Streptococcus pneumoniae Virulence by Inhibiting Pneumolysin Release.
    Greene NG, Narciso AR, Filipe SR, Camilli A.
    PLoS Pathog; 2015 Jun 11; 11(6):e1004996. PubMed ID: 26114646
    [Abstract] [Full Text] [Related]

  • 36. Pyruvate oxidase of Streptococcus pneumoniae contributes to pneumolysin release.
    Bryant JC, Dabbs RC, Oswalt KL, Brown LR, Rosch JW, Seo KS, Donaldson JR, McDaniel LS, Thornton JA.
    BMC Microbiol; 2016 Nov 09; 16(1):271. PubMed ID: 27829373
    [Abstract] [Full Text] [Related]

  • 37. Critical involvement of pneumolysin in production of interleukin-1alpha and caspase-1-dependent cytokines in infection with Streptococcus pneumoniae in vitro: a novel function of pneumolysin in caspase-1 activation.
    Shoma S, Tsuchiya K, Kawamura I, Nomura T, Hara H, Uchiyama R, Daim S, Mitsuyama M.
    Infect Immun; 2008 Apr 09; 76(4):1547-57. PubMed ID: 18195026
    [Abstract] [Full Text] [Related]

  • 38. Betulin attenuates pneumolysin-induced cell injury and DNA damage.
    Qi Z, Guo Y, Zhang H, Yu Q, Zhang P.
    J Appl Microbiol; 2021 Mar 09; 130(3):843-851. PubMed ID: 32621771
    [Abstract] [Full Text] [Related]

  • 39. Isorhamnetin as a novel inhibitor of pneumolysin against Streptococcus pneumoniae infection in vivo/in vitro.
    Zou Y, Wang H, Fang J, Sun H, Deng X, Wang J, Deng Y, Chi G.
    Microb Pathog; 2023 Dec 09; 185():106382. PubMed ID: 37839759
    [Abstract] [Full Text] [Related]

  • 40. Targeted small molecule inhibitors blocking the cytolytic effects of pneumolysin and homologous toxins.
    Aziz UBA, Saoud A, Bermudez M, Mieth M, Atef A, Rudolf T, Arkona C, Trenkner T, Böttcher C, Ludwig K, Hoelzemer A, Hocke AC, Wolber G, Rademann J.
    Nat Commun; 2024 Apr 26; 15(1):3537. PubMed ID: 38670939
    [Abstract] [Full Text] [Related]


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