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Journal Abstract Search

239 related items for PubMed ID: 31785856

  • 1. The synthetic flavanone 6-methoxy-2-(naphthalen-1-yl)chroman-4-one induces apoptosis and activation of the MAPK pathway in human U-937 leukaemia cells.
    Saavedra E, Del Rosario H, Brouard I, Hernández-Garcés J, García C, Quintana J, Estévez F.
    Bioorg Chem; 2020 Jan; 94():103450. PubMed ID: 31785856
    [Abstract] [Full Text] [Related]

  • 2. Design and synthesis of naphthylchalcones as novel anti-leukaemia agents.
    Leitão EPT, Ascenso OS, Santos de Almeida T, González I, Hernández I, Quintana J, Estévez F, Rijo P.
    Bioorg Chem; 2021 Dec; 117():105348. PubMed ID: 34736139
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach.
    Preti D, Romagnoli R, Rondanin R, Cacciari B, Hamel E, Balzarini J, Liekens S, Schols D, Estévez-Sarmiento F, Quintana J, Estévez F.
    J Enzyme Inhib Med Chem; 2018 Dec; 33(1):1225-1238. PubMed ID: 30141353
    [Abstract] [Full Text] [Related]

  • 4. Structure-activity relationships reveal a 2-furoyloxychalcone as a potent cytotoxic and apoptosis inducer for human U-937 and HL-60 leukaemia cells.
    Del Rosario H, Saavedra E, Brouard I, González-Santana D, García C, Spínola-Lasso E, Tabraue C, Quintana J, Estévez F.
    Bioorg Chem; 2022 Oct; 127():105926. PubMed ID: 35717804
    [Abstract] [Full Text] [Related]

  • 5. 3'-Hydroxy-3,4'-dimethoxyflavone-induced cell death in human leukaemia cells is dependent on caspases and reactive oxygen species and attenuated by the inhibition of JNK/SAPK.
    Estévez-Sarmiento F, Hernández E, Brouard I, León F, García C, Quintana J, Estévez F.
    Chem Biol Interact; 2018 May 25; 288():1-11. PubMed ID: 29630880
    [Abstract] [Full Text] [Related]

  • 6. 6'-Benzyloxy-4-bromo-2'-hydroxychalcone is cytotoxic against human leukaemia cells and induces caspase-8- and reactive oxygen species-dependent apoptosis.
    Saavedra E, Del Rosario H, Brouard I, Quintana J, Estévez F.
    Chem Biol Interact; 2019 Jan 25; 298():137-145. PubMed ID: 30576621
    [Abstract] [Full Text] [Related]

  • 7. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK, Wang ZL, Pan ST, Ding HQ, Au GH, He ZX, Zhou ZW, Xiao G, Yang YX, Zhang X, Yang T, Chen XW, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Jan 25; 9():1555-84. PubMed ID: 25792811
    [Abstract] [Full Text] [Related]

  • 8. Synthesis, antiproliferative and apoptosis induction potential activities of novel bis(indolyl)hydrazide-hydrazone derivatives.
    Sreenivasulu R, Reddy KT, Sujitha P, Kumar CG, Raju RR.
    Bioorg Med Chem; 2019 Mar 15; 27(6):1043-1055. PubMed ID: 30773423
    [Abstract] [Full Text] [Related]

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  • 10. Synthesis and anti-cancer activity evaluation of new dimethoxylated chalcone and flavanone analogs.
    Ketabforoosh SH, Kheirollahi A, Safavi M, Esmati N, Ardestani SK, Emami S, Firoozpour L, Shafiee A, Foroumadi A.
    Arch Pharm (Weinheim); 2014 Nov 15; 347(11):853-60. PubMed ID: 25201534
    [Abstract] [Full Text] [Related]

  • 11. Antiproliferative activity and apoptosis induction by 3',4'-dibenzyloxyflavonol on human leukemia cells.
    Said M, Brouard I, Quintana J, Estévez F.
    Chem Biol Interact; 2017 Apr 25; 268():13-23. PubMed ID: 28235426
    [Abstract] [Full Text] [Related]

  • 12. Halogenated flavanones as potential apoptosis-inducing agents: synthesis and biological activity evaluation.
    Safavi M, Esmati N, Ardestani SK, Emami S, Ajdari S, Davoodi J, Shafiee A, Foroumadi A.
    Eur J Med Chem; 2012 Dec 25; 58():573-80. PubMed ID: 23174316
    [Abstract] [Full Text] [Related]

  • 13. A novel synthetic analog of Militarin, MA-1 induces mitochondrial dependent apoptosis by ROS generation in human lung cancer cells.
    Yoon DH, Lim MH, Lee YR, Sung GH, Lee TH, Jeon BH, Cho JY, Song WO, Park H, Choi S, Kim TW.
    Toxicol Appl Pharmacol; 2013 Dec 15; 273(3):659-71. PubMed ID: 24161344
    [Abstract] [Full Text] [Related]

  • 14. Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.
    Ou YC, Yang CR, Cheng CL, Raung SL, Hung YY, Chen CJ.
    Eur J Pharmacol; 2007 Jun 01; 563(1-3):49-60. PubMed ID: 17341418
    [Abstract] [Full Text] [Related]

  • 15. Evaluation of Multifunctional Hybrid Analogs for Stilbenes, Chalcones and Flavanones.
    Cagir A, Odaci B, Varol M, Akcok I, Okur O, Koparal AT.
    Anticancer Agents Med Chem; 2018 Feb 07; 17(14):1915-1923. PubMed ID: 28554313
    [Abstract] [Full Text] [Related]

  • 16. Structurally related antitumor effects of flavanones in vitro and in vivo: involvement of caspase 3 activation, p21 gene expression, and reactive oxygen species production.
    Shen SC, Ko CH, Tseng SW, Tsai SH, Chen YC.
    Toxicol Appl Pharmacol; 2004 Jun 01; 197(2):84-95. PubMed ID: 15163544
    [Abstract] [Full Text] [Related]

  • 17. Antileukemia activity of MSFTZ-a novel flavanone analog.
    He Q, Li R, Fang L, Ying H, Hu Y, Yang B.
    Anticancer Drugs; 2006 Jul 01; 17(6):641-7. PubMed ID: 16917209
    [Abstract] [Full Text] [Related]

  • 18. MSFTZ, a flavanone derivative, induces human hepatoma cell apoptosis via a reactive oxygen species- and caspase-dependent mitochondrial pathway.
    Ying M, Tu C, Ying H, Hu Y, He Q, Yang B.
    J Pharmacol Exp Ther; 2008 Jun 01; 325(3):758-65. PubMed ID: 18323457
    [Abstract] [Full Text] [Related]

  • 19. Involvement of histone H3 phosphorylation through p38 MAPK pathway activation in casticin-induced cytocidal effects against the human promyelocytic cell line HL-60.
    Kikuchi H, Yuan B, Yuhara E, Takagi N, Toyoda H.
    Int J Oncol; 2013 Dec 01; 43(6):2046-56. PubMed ID: 24064676
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and biological evaluation of alpha-bromoacryloylamido indolyl pyridinyl propenones as potent apoptotic inducers in human leukaemia cells.
    Romagnoli R, Prencipe F, Lopez-Cara LC, Oliva P, Baraldi S, Baraldi PG, Estévez-Sarmiento F, Quintana J, Estévez F.
    J Enzyme Inhib Med Chem; 2018 Dec 01; 33(1):727-742. PubMed ID: 29620429
    [Abstract] [Full Text] [Related]

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