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Journal Abstract Search

76 related items for PubMed ID: 3179320

  • 1. Design, synthesis and antithrombin activity for conformationally restricted analogs of peptide anticoagulants based on the C-terminal region of the leech peptide, hirudin.
    Krstenansky JL, Owen TJ, Yates MT, Mao SJ.
    Biochim Biophys Acta; 1988 Nov 02; 957(1):53-9. PubMed ID: 3179320
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  • 2. Conformationally restricted thrombin inhibitors resistant to proteolytic digestion.
    Szewczuk Z, Gibbs BF, Yue SY, Purisima EO, Konishi Y.
    Biochemistry; 1992 Sep 29; 31(38):9132-40. PubMed ID: 1390700
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  • 3. N-terminal requirements of small peptide anticoagulants based on hirudin54-65.
    Owen TJ, Krstenansky JL, Yates MT, Mao SJ.
    J Med Chem; 1988 May 29; 31(5):1009-11. PubMed ID: 3361570
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  • 6. Anticoagulant peptides; synthesis, stability and antithrombin activity of hirudin C-terminal-related peptides and their disulfated analog.
    Okayama T, Muramatsu R, Seki S, Nukui E, Hagiwara M, Hayashi H, Morikawa T.
    Chem Pharm Bull (Tokyo); 1996 Jul 29; 44(7):1344-50. PubMed ID: 8706141
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  • 8. Incorporation of noncoded amino acids into the N-terminal domain 1-47 of hirudin yields a highly potent and selective thrombin inhibitor.
    De Filippis V, Russo I, Vindigni A, Di Cera E, Salmaso S, Fontana A.
    Protein Sci; 1999 Oct 29; 8(10):2213-7. PubMed ID: 10548068
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  • 9. Efficient targeted anticoagulant with active RGD motif.
    Bi Q, Zhou X, Cen X, Qu H, Luo J, Huang Y, Zhu S.
    Thromb Res; 2007 Oct 29; 120(4):541-7. PubMed ID: 17222892
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  • 10. Hirunorms are true hirudin mimetics. The crystal structure of human alpha-thrombin-hirunorm V complex.
    De Simone G, Lombardi A, Galdiero S, Nastri F, Della Morte R, Staiano N, Pedone C, Bolognesi M, Pavone V.
    Protein Sci; 1998 Feb 29; 7(2):243-53. PubMed ID: 9521099
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  • 11. Structure-function and refolding studies of the thrombin-specific inhibitor hirudin.
    Johnson PH, Sze P, Winant RC, Hudson D, Underhill P, Lazar JB, Olsen C, Almquist R.
    Haemostasis; 1991 Feb 29; 21 Suppl 1():41-8. PubMed ID: 1894196
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  • 12. Amino acids and peptides. XVI. Synthesis of N-terminal tetrapeptide analogs of fibrin alpha-chain and their inhibitory effects on fibrinogen/thrombin clotting.
    Kawasaki K, Hirase K, Miyano M, Tsuji T, Iwamoto M.
    Chem Pharm Bull (Tokyo); 1992 Dec 29; 40(12):3253-60. PubMed ID: 1294328
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  • 13. Active site-directed thrombin inhibitors: alpha-hydroxyacyl-prolyl-arginals. New orally active stable analogs of D-Phe-Pro-Arg-H.
    Bajusz S, Barabás E, Fauszt I, Fehér A, Horváth G, Juhász A, Szabó AG, Széll E.
    Bioorg Med Chem; 1995 Aug 29; 3(8):1079-89. PubMed ID: 7582981
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  • 14. Antithrombin agents as anticoagulants and antithrombotics: implications in drug development.
    Fareed J, Callas D, Hoppensteadt DA, Lewis BE, Bick RL, Walenga JM.
    Semin Hematol; 1999 Jan 29; 36(1 Suppl 1):42-56. PubMed ID: 9930564
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  • 15. [From fibrinogen and hirudin to synthetic anticoagulants. Rational design of thrombin inhibitors].
    Steinmetzer T, Stürzebecher J.
    Pharm Unserer Zeit; 2004 Jan 29; 33(3):196-205. PubMed ID: 15208908
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  • 17. Rational design of true hirudin mimetics: synthesis and characterization of multisite-directed alpha-thrombin inhibitors.
    Lombardi A, Nastri F, Della Morte R, Rossi A, De Rosa A, Staiano N, Pedone C, Pavone V.
    J Med Chem; 1996 May 10; 39(10):2008-17. PubMed ID: 8642559
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  • 20. Conformationally constrained analogs of protein kinase inhibitor (6-22)amide: effect of turn structures in the center of the peptide on inhibition of cAMP-dependent protein kinase.
    Glass DB, Trewhella J, Mitchell RD, Walsh DA.
    Protein Sci; 1995 Mar 10; 4(3):405-15. PubMed ID: 7795524
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