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Journal Abstract Search

230 related items for PubMed ID: 31810115

  • 1. Thiamine mimetics sulbutiamine and benfotiamine as a nutraceutical approach to anticancer therapy.
    Jonus HC, Byrnes CC, Kim J, Valle ML, Bartlett MG, Said HM, Zastre JA.
    Biomed Pharmacother; 2020 Jan; 121():109648. PubMed ID: 31810115
    [Abstract] [Full Text] [Related]

  • 2. High-dose vitamin B1 reduces proliferation in cancer cell lines analogous to dichloroacetate.
    Hanberry BS, Berger R, Zastre JA.
    Cancer Chemother Pharmacol; 2014 Mar; 73(3):585-94. PubMed ID: 24452394
    [Abstract] [Full Text] [Related]

  • 3. Metabolic Flexibility in Cancer: Targeting the Pyruvate Dehydrogenase Kinase:Pyruvate Dehydrogenase Axis.
    Woolbright BL, Rajendran G, Harris RA, Taylor JA.
    Mol Cancer Ther; 2019 Oct; 18(10):1673-1681. PubMed ID: 31511353
    [Abstract] [Full Text] [Related]

  • 4. Targeting pyruvate dehydrogenase kinase signaling in the development of effective cancer therapy.
    Anwar S, Shamsi A, Mohammad T, Islam A, Hassan MI.
    Biochim Biophys Acta Rev Cancer; 2021 Aug; 1876(1):188568. PubMed ID: 34023419
    [Abstract] [Full Text] [Related]

  • 5. Could thiamine pyrophosphate be a regulator of the nitric oxide synthesis in the endothelial cell of diabetic patients?
    Alcázar-Leyva S, Alvarado-Vásquez N.
    Med Hypotheses; 2011 May; 76(5):629-31. PubMed ID: 21288652
    [Abstract] [Full Text] [Related]

  • 6. Benfotiamine, a synthetic S-acyl thiamine derivative, has different mechanisms of action and a different pharmacological profile than lipid-soluble thiamine disulfide derivatives.
    Volvert ML, Seyen S, Piette M, Evrard B, Gangolf M, Plumier JC, Bettendorff L.
    BMC Pharmacol; 2008 Jun 12; 8():10. PubMed ID: 18549472
    [Abstract] [Full Text] [Related]

  • 7. Differences in the efficiency of 3-deazathiamine and oxythiamine pyrophosphates as inhibitors of pyruvate dehydrogenase complex and growth of HeLa cells in vitro.
    Grabowska E, Czerniecka M, Czyżewska U, Zambrzycka A, Łotowski Z, Tylicki A.
    J Enzyme Inhib Med Chem; 2021 Dec 12; 36(1):122-129. PubMed ID: 33187452
    [Abstract] [Full Text] [Related]

  • 8. Vitamin C activates pyruvate dehydrogenase (PDH) targeting the mitochondrial tricarboxylic acid (TCA) cycle in hypoxic KRAS mutant colon cancer.
    Cenigaonandia-Campillo A, Serna-Blasco R, Gómez-Ocabo L, Solanes-Casado S, Baños-Herraiz N, Puerto-Nevado LD, Cañas JA, Aceñero MJ, García-Foncillas J, Aguilera Ó.
    Theranostics; 2021 Dec 12; 11(8):3595-3606. PubMed ID: 33664850
    [Abstract] [Full Text] [Related]

  • 9. Targeting the PDK/PDH axis to reverse metabolic abnormalities by structure-based virtual screening with in vitro and in vivo experiments.
    Yue J, Xu J, Yin Y, Shu Y, Li Y, Li T, Zou Z, Wang Z, Li F, Zhang M, Liang S, He X, Liu Z, Wang Y.
    Int J Biol Macromol; 2024 Mar 12; 262(Pt 1):129970. PubMed ID: 38325689
    [Abstract] [Full Text] [Related]

  • 10. Furan-based inhibitors of pyruvate dehydrogenase: SAR study, biochemical evaluation and computational analysis.
    Chan AHY, Ho TCS, Parle DR, Leeper FJ.
    Org Biomol Chem; 2023 Feb 22; 21(8):1755-1763. PubMed ID: 36723268
    [Abstract] [Full Text] [Related]

  • 11. Effects of thiamine and benfotiamine on intracellular glucose metabolism and relevance in the prevention of diabetic complications.
    Beltramo E, Berrone E, Tarallo S, Porta M.
    Acta Diabetol; 2008 Sep 22; 45(3):131-41. PubMed ID: 18581039
    [Abstract] [Full Text] [Related]

  • 12. Targeting the pyruvate dehydrogenase complex/pyruvate dehydrogenase kinase (PDC/PDK) axis to discover potent PDK inhibitors through structure-based virtual screening and pharmacological evaluation.
    Gan L, Yang Y, Liang Z, Zhang M, He Y, Zhang SL.
    Eur J Med Chem; 2024 Jan 15; 264():116008. PubMed ID: 38056298
    [Abstract] [Full Text] [Related]

  • 13. The Effects of Thiamine on Breast Cancer Cells.
    Liu X, Montissol S, Uber A, Ganley S, Grossestreuer AV, Berg K, Heydrick S, Donnino MW.
    Molecules; 2018 Jun 16; 23(6):. PubMed ID: 29914147
    [Abstract] [Full Text] [Related]

  • 14. Thiamine and benfotiamine prevent stress-induced suppression of hippocampal neurogenesis in mice exposed to predation without affecting brain thiamine diphosphate levels.
    Vignisse J, Sambon M, Gorlova A, Pavlov D, Caron N, Malgrange B, Shevtsova E, Svistunov A, Anthony DC, Markova N, Bazhenova N, Coumans B, Lakaye B, Wins P, Strekalova T, Bettendorff L.
    Mol Cell Neurosci; 2017 Jul 16; 82():126-136. PubMed ID: 28506637
    [Abstract] [Full Text] [Related]

  • 15. Metabolic Connection of Inflammatory Pain: Pivotal Role of a Pyruvate Dehydrogenase Kinase-Pyruvate Dehydrogenase-Lactic Acid Axis.
    Jha MK, Song GJ, Lee MG, Jeoung NH, Go Y, Harris RA, Park DH, Kook H, Lee IK, Suk K.
    J Neurosci; 2015 Oct 21; 35(42):14353-69. PubMed ID: 26490872
    [Abstract] [Full Text] [Related]

  • 16. ROS production induced by BRAF inhibitor treatment rewires metabolic processes affecting cell growth of melanoma cells.
    Cesi G, Walbrecq G, Zimmer A, Kreis S, Haan C.
    Mol Cancer; 2017 Jun 08; 16(1):102. PubMed ID: 28595656
    [Abstract] [Full Text] [Related]

  • 17. Real-time hyperpolarized 13C magnetic resonance detects increased pyruvate oxidation in pyruvate dehydrogenase kinase 2/4-double knockout mouse livers.
    Sharma G, Wu CY, Wynn RM, Gui W, Malloy CR, Sherry AD, Chuang DT, Khemtong C.
    Sci Rep; 2019 Nov 11; 9(1):16480. PubMed ID: 31712597
    [Abstract] [Full Text] [Related]

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  • 19. Benfotiamine accelerates the healing of ischaemic diabetic limbs in mice through protein kinase B/Akt-mediated potentiation of angiogenesis and inhibition of apoptosis.
    Gadau S, Emanueli C, Van Linthout S, Graiani G, Todaro M, Meloni M, Campesi I, Invernici G, Spillmann F, Ward K, Madeddu P.
    Diabetologia; 2006 Feb 11; 49(2):405-20. PubMed ID: 16416271
    [Abstract] [Full Text] [Related]

  • 20. Thiamine analogues featuring amino-oxetanes as potent and selective inhibitors of pyruvate dehydrogenase.
    Chan AHY, Ho TCS, Leeper FJ.
    Bioorg Med Chem Lett; 2024 Jan 15; 98():129571. PubMed ID: 38036274
    [Abstract] [Full Text] [Related]

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