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Journal Abstract Search


185 related items for PubMed ID: 3181288

  • 1. Inhibition of catechol-O-methyltransferase activity by two novel disubstituted catechols in the rat.
    Nissinen E, Lindén IB, Schultz E, Kaakkola S, Männistö PT, Pohto P.
    Eur J Pharmacol; 1988 Aug 24; 153(2-3):263-9. PubMed ID: 3181288
    [Abstract] [Full Text] [Related]

  • 2. Effect of a novel catechol-O-methyltransferase inhibitor, nitecapone, on the metabolism of L-dopa in healthy volunteers.
    Kaakkola S, Gordin A, Järvinen M, Wikberg T, Schultz E, Nissinen E, Pentikäinen PJ, Rita H.
    Clin Neuropharmacol; 1990 Oct 24; 13(5):436-47. PubMed ID: 2272023
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of rat liver and duodenum soluble catechol-O-methyltransferase by a tight-binding inhibitor OR-462.
    Schultz E, Nissinen E.
    Biochem Pharmacol; 1989 Nov 15; 38(22):3953-6. PubMed ID: 2597177
    [Abstract] [Full Text] [Related]

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  • 5. Favorable effect of catechol-O-methyltransferase inhibition by OR-462 in experimental models of Parkinson's disease.
    Lindén IB, Nissinen E, Etemadzadeh E, Kaakkola S, Männistö P, Pohto P.
    J Pharmacol Exp Ther; 1988 Oct 15; 247(1):289-93. PubMed ID: 3171977
    [Abstract] [Full Text] [Related]

  • 6. Different in vivo properties of three new inhibitors of catechol O-methyltransferase in the rat.
    Männistö PT, Tuomainen P, Tuominen RK.
    Br J Pharmacol; 1992 Mar 15; 105(3):569-74. PubMed ID: 1628144
    [Abstract] [Full Text] [Related]

  • 7. Peripheral and central inhibitors of catechol-O-methyl transferase: effects on liver and brain COMT activity and L-DOPA metabolism.
    Brannan T, Prikhojan A, Yahr MD.
    J Neural Transm (Vienna); 1997 Mar 15; 104(1):77-87. PubMed ID: 9085195
    [Abstract] [Full Text] [Related]

  • 8. Effect of nitecapone (OR-462) on the pharmacokinetics of levodopa and 3-O-methyldopa formation in cynomolgus monkeys.
    Cedarbaum JM, Léger G, Reches A, Guttman M.
    Clin Neuropharmacol; 1990 Dec 15; 13(6):544-52. PubMed ID: 2276119
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of human erythrocyte and gastroduodenal catechol-O-methyltransferase activity by nitecapone.
    Schultz E, Tarpila S, Bäckström AC, Gordin A, Nissinen E, Pohto P.
    Eur J Clin Pharmacol; 1991 Dec 15; 40(6):577-80. PubMed ID: 1884738
    [Abstract] [Full Text] [Related]

  • 10. Reduction of circulating 3-O-methyldopa by inhibition of catechol-O-methyltransferase with OR-611 and OR-462 in cynomolgus monkeys: implications for the treatment of Parkinson's disease.
    Cedarbaum JM, Leger G, Guttman M.
    Clin Neuropharmacol; 1991 Aug 15; 14(4):330-42. PubMed ID: 1913700
    [Abstract] [Full Text] [Related]

  • 11. Effect of high single doses of levodopa and carbidopa on brain dopamine and its metabolites: modulation by selective inhibitors of monoamine oxidase and/or catechol-O-methyltransferase in the male rat.
    Männistö PT, Tuomainen P.
    Naunyn Schmiedebergs Arch Pharmacol; 1991 Oct 15; 344(4):412-8. PubMed ID: 1766471
    [Abstract] [Full Text] [Related]

  • 12. Catechol-O-methyltransferase inhibition in erythrocytes and liver by BIA 3-202 (1-[3,4-dibydroxy-5-nitrophenyl]-2-phenyl-ethanone).
    Soares-da-Silva P, Vieira-Coelho MA, Parada A.
    Pharmacol Toxicol; 2003 Jun 15; 92(6):272-8. PubMed ID: 12787259
    [Abstract] [Full Text] [Related]

  • 13. Nitrocatechol Derivatives of Chalcone as Inhibitors of Monoamine Oxidase and Catechol-O-Methyltransferase.
    Engelbrecht I, Petzer JP, Petzer A.
    Cent Nerv Syst Agents Med Chem; 2018 Jun 15; 18(2):115-127. PubMed ID: 29697034
    [Abstract] [Full Text] [Related]

  • 14. Comparison of two new inhibitors of catechol O-methylation on striatal dopamine metabolism: a microdialysis study in rats.
    Törnwall M, Kaakkola S, Tuomainen P, Kask A, Männistö PT.
    Br J Pharmacol; 1994 May 15; 112(1):13-8. PubMed ID: 7518301
    [Abstract] [Full Text] [Related]

  • 15. Neurochemical and psychomotor interactions of new selective COMT inhibitors with clorgyline and nomifensine in levodopa-treated rats and mice.
    Törnwall M, Tuomainen P, Männistö PT.
    Arch Int Pharmacodyn Ther; 1992 May 15; 320():5-20. PubMed ID: 1300941
    [Abstract] [Full Text] [Related]

  • 16. Pharmacokinetic-pharmacodynamic interaction between nebicapone, a novel catechol-o-methyltransferase inhibitor, and controlled-release levodopa/carbidopa 200 mg/50 mg : randomized, double-blind, placebo-controlled, crossover study in healthy subjects.
    Vaz-da-Silva M, Loureiro AI, Nunes T, Lopes C, Rocha J, Machado R, Costa R, Torrão L, Falcão A, Wright L, Almeida L, Soares-da-Silva P.
    Drugs R D; 2008 May 15; 9(6):435-46. PubMed ID: 18989992
    [Abstract] [Full Text] [Related]

  • 17. Effects of catechol-O-methyltransferase inhibitors and L-3,4-dihydroxyphenylalanine with or without carbidopa on extracellular dopamine in rat striatum.
    Kaakkola S, Wurtman RJ.
    J Neurochem; 1993 Jan 15; 60(1):137-44. PubMed ID: 8417137
    [Abstract] [Full Text] [Related]

  • 18. Pharmacokinetic-pharmacodynamic interaction between BIA 3-202, a novel COMT inhibitor, and levodopa/carbidopa.
    Almeida L, Vaz-da-Silva M, Silveira P, Falcão A, Maia J, Loureiro A, Torrão L, Machado R, Wright L, Soares-da-Silva P.
    Clin Neuropharmacol; 2004 Jan 15; 27(1):17-24. PubMed ID: 15090932
    [Abstract] [Full Text] [Related]

  • 19. Catechol-O-methyltransferase inhibition attenuates levodopa toxicity in mesencephalic dopamine neurons.
    Storch A, Blessing H, Bareiss M, Jankowski S, Ling ZD, Carvey P, Schwarz J.
    Mol Pharmacol; 2000 Mar 15; 57(3):589-94. PubMed ID: 10692500
    [Abstract] [Full Text] [Related]

  • 20. The effect of catechol-O-methyl transferase inhibition by entacapone on the pharmacokinetics and metabolism of levodopa in healthy volunteers.
    Keränen T, Gordin A, Harjola VP, Karlsson M, Korpela K, Pentikäinen PJ, Rita H, Seppälä L, Wikberg T.
    Clin Neuropharmacol; 1993 Apr 15; 16(2):145-56. PubMed ID: 8477410
    [Abstract] [Full Text] [Related]


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