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Journal Abstract Search

424 related items for PubMed ID: 31818003

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  • 2. CP-25 inhibits PGE2-induced angiogenesis by down-regulating EP4/AC/cAMP/PKA-mediated GRK2 translocation.
    Han CC, Liu Q, Zhang Y, Li YF, Cui DQ, Luo TT, Zhang YW, Wang XM, Wang C, Ma Y, Wei W.
    Clin Sci (Lond); 2020 Feb 14; 134(3):331-347. PubMed ID: 31967309
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  • 5. TNF-α impairs EP4 signaling through the association of TRAF2-GRK2 in primary fibroblast-like synoviocytes.
    Tai Y, Huang B, Guo PP, Wang Z, Zhou ZW, Wang MM, Sun HF, Hu Y, Xu SL, Zhang LL, Wang QT, Wei W.
    Acta Pharmacol Sin; 2022 Feb 14; 43(2):401-416. PubMed ID: 33859345
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  • 6. Angiotensin II Type 2 Receptor Modulates Synovial Macrophage Polarization by Inhibiting GRK2 Membrane Translocation in a Rat Model of Collagen-Induced Arthritis.
    Wang X, Tu J, Jiang J, Zhang Q, Liu Q, Körner H, Wu J, Wu H, Wei W.
    J Immunol; 2020 Dec 01; 205(11):3141-3153. PubMed ID: 33148713
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  • 7. Pharmacological characterisation of CR6086, a potent prostaglandin E2 receptor 4 antagonist, as a new potential disease-modifying anti-rheumatic drug.
    Caselli G, Bonazzi A, Lanza M, Ferrari F, Maggioni D, Ferioli C, Giambelli R, Comi E, Zerbi S, Perrella M, Letari O, Di Luccio E, Colovic M, Persiani S, Zanelli T, Mennuni L, Piepoli T, Rovati LC.
    Arthritis Res Ther; 2018 Mar 01; 20(1):39. PubMed ID: 29490676
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  • 8. GRK2 Mediates Macrophage Polarization by Regulating EP4-cAMP-pCREB Signaling in Ulcerative Colitis and the Therapeutic Effect of Paroxetine on Mice with DSS-Induced Colitis.
    Zhang J, Zhang X, Lu M, Chang Y, Wang Q, Tu J, Wu H, Wang C, Hong Z, Xiong M, Song L, Wei W.
    Pharmaceuticals (Basel); 2023 Apr 28; 16(5):. PubMed ID: 37242446
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  • 11. Prostaglandin E2-induced IL-23p19 subunit is regulated by cAMP-responsive element-binding protein and C/AATT enhancer-binding protein β in bone marrow-derived dendritic cells.
    Kocieda VP, Adhikary S, Emig F, Yen JH, Toscano MG, Ganea D.
    J Biol Chem; 2012 Oct 26; 287(44):36922-35. PubMed ID: 22977257
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  • 12. Endogenous prostaglandin E2 amplifies IL-33 production by macrophages through an E prostanoid (EP)2/EP4-cAMP-EPAC-dependent pathway.
    Samuchiwal SK, Balestrieri B, Raff H, Boyce JA.
    J Biol Chem; 2017 May 19; 292(20):8195-8206. PubMed ID: 28341741
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  • 16. Prostaglandin E2 suppresses hCAP18/LL-37 expression in human macrophages via EP2/EP4: implications for treatment of Mycobacterium tuberculosis infection.
    Wan M, Tang X, Rekha RS, Muvva SSVJR, Brighenti S, Agerberth B, Haeggström JZ.
    FASEB J; 2018 May 19; 32(5):2827-2840. PubMed ID: 29401596
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  • 17. Targeted inhibition of GRK2 kinase domain by CP-25 to reverse fibroblast-like synoviocytes dysfunction and improve collagen-induced arthritis in rats.
    Han C, Li Y, Zhang Y, Wang Y, Cui D, Luo T, Zhang Y, Liu Q, Li H, Wang C, Xu D, Ma Y, Wei W.
    Acta Pharm Sin B; 2021 Jul 19; 11(7):1835-1852. PubMed ID: 34386323
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  • 18. Low nociceptor GRK2 prolongs prostaglandin E2 hyperalgesia via biased cAMP signaling to Epac/Rap1, protein kinase Cepsilon, and MEK/ERK.
    Eijkelkamp N, Wang H, Garza-Carbajal A, Willemen HL, Zwartkruis FJ, Wood JN, Dantzer R, Kelley KW, Heijnen CJ, Kavelaars A.
    J Neurosci; 2010 Sep 22; 30(38):12806-15. PubMed ID: 20861385
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  • 20. Characterization of the Signaling Modalities of Prostaglandin E2 Receptors EP2 and EP4 Reveals Crosstalk and a Role for Microtubules.
    Vleeshouwers W, van den Dries K, de Keijzer S, Joosten B, Lidke DS, Cambi A.
    Front Immunol; 2020 Sep 22; 11():613286. PubMed ID: 33643295
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