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Journal Abstract Search

179 related items for PubMed ID: 31837830

  • 1. Apoptosis: A target for anticancer therapy with novel cyanopyridines.
    Ismail MMF, Farrag AM, Harras MF, Ibrahim MH, Mehany ABM.
    Bioorg Chem; 2020 Jan; 94():103481. PubMed ID: 31837830
    [Abstract] [Full Text] [Related]

  • 2. Eco-friendly synthesis of novel cyanopyridine derivatives and their anticancer and PIM-1 kinase inhibitory activities.
    Abouzid KAM, Al-Ansary GH, El-Naggar AM.
    Eur J Med Chem; 2017 Jul 07; 134():357-365. PubMed ID: 28431341
    [Abstract] [Full Text] [Related]

  • 3. New cyanopyridine-based scaffold as PIM-1 inhibitors and apoptotic inducers: Synthesis and SARs study.
    Farrag AM, Ibrahim MH, Mehany ABM, Ismail MMF.
    Bioorg Chem; 2020 Dec 07; 105():104378. PubMed ID: 33099167
    [Abstract] [Full Text] [Related]

  • 4. Utilization of cyanopyridine in design and synthesis of first-in-class anticancer dual acting PIM-1 kinase/HDAC inhibitors.
    Bass AKA, Nageeb EM, El-Zoghbi MS, Mohamed MFA, Badr M, Abuo-Rahma GEA.
    Bioorg Chem; 2022 Feb 07; 119():105564. PubMed ID: 34959179
    [Abstract] [Full Text] [Related]

  • 5. Discovery of new pyrimidine-5-carbonitrile derivatives as anticancer agents targeting EGFRWT and EGFRT790M.
    Nasser AA, Eissa IH, Oun MR, El-Zahabi MA, Taghour MS, Belal A, Saleh AM, Mehany ABM, Luesch H, Mostafa AE, Afifi WM, Rocca JR, Mahdy HA.
    Org Biomol Chem; 2020 Oct 07; 18(38):7608-7634. PubMed ID: 32959865
    [Abstract] [Full Text] [Related]

  • 6. Nicotinonitrile-derived apoptotic inducers: Design, synthesis, X-ray crystal structure and Pim kinase inhibition.
    Aboukhatwa SM, Ibrahim AO, Aoyama H, Al-Behery AS, Shaldam MA, El-Ashmawy G, Tawfik HO.
    Bioorg Chem; 2022 Dec 07; 129():106126. PubMed ID: 36108589
    [Abstract] [Full Text] [Related]

  • 7. Biological Activity, Apoptotic Induction and Cell Cycle Arrest of New Hydrazonoyl Halides Derivatives.
    Mohamed MF, Hassaneen HM, Elzayat EM, El-Hallouty SM, El-Manawaty M, Saleh FM, Mohamed Y, El-Zohiry D, Fahmy G, Abdelaal N, Hassanin N, Hossam N.
    Anticancer Agents Med Chem; 2019 Dec 07; 19(9):1141-1149. PubMed ID: 30843494
    [Abstract] [Full Text] [Related]

  • 8. Novel ciprofloxacin hybrids using biology oriented drug synthesis (BIODS) approach: Anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis, topoisomerase II inhibition, and antibacterial activity.
    Kassab AE, Gedawy EM.
    Eur J Med Chem; 2018 Apr 25; 150():403-418. PubMed ID: 29547830
    [Abstract] [Full Text] [Related]

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  • 10. Discovery of Novel 3-Cyanopyridines as Survivin Modulators and Apoptosis Inducers.
    Sabour R, Harras MF, Mohamed Al Kamaly O, Altwaijry N.
    Molecules; 2020 Oct 22; 25(21):. PubMed ID: 33105831
    [Abstract] [Full Text] [Related]

  • 11. Design and synthesis of thienopyrimidine urea derivatives with potential cytotoxic and pro-apoptotic activity against breast cancer cell line MCF-7.
    Abdelhaleem EF, Abdelhameid MK, Kassab AE, Kandeel MM.
    Eur J Med Chem; 2018 Jan 01; 143():1807-1825. PubMed ID: 29133058
    [Abstract] [Full Text] [Related]

  • 12. Novel Nicotinonitrile Derivatives Bearing Imino Moieties Enhance Apoptosis and Inhibit Tyrosine Kinase.
    El-Hashash MA, El-Bordany EA, Marzouk MI, El-Naggar AM, Nawar TMS, El-Sayed WM.
    Anticancer Agents Med Chem; 2018 Jan 01; 18(11):1589-1598. PubMed ID: 29745342
    [Abstract] [Full Text] [Related]

  • 13. Development of novel cyanopyridines as PIM-1 kinase inhibitors with potent anti-prostate cancer activity: Synthesis, biological evaluation, nanoparticles formulation and molecular dynamics simulation.
    Ibrahim MH, Harras MF, Mostafa SK, Mohyeldin SM, Al Kamaly O, Altwaijry N, Sabour R.
    Bioorg Chem; 2022 Dec 01; 129():106122. PubMed ID: 36084418
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and biological evaluation of new steroidal pyridines as potential anti-prostate cancer agents.
    Shi YK, Wang B, Shi XL, Zhao YD, Yu B, Liu HM.
    Eur J Med Chem; 2018 Feb 10; 145():11-22. PubMed ID: 29310026
    [Abstract] [Full Text] [Related]

  • 15. Dual VEGFR-2/PIM-1 kinase inhibition towards surmounting the resistance to antiangiogenic agents via hybrid pyridine and thienopyridine-based scaffolds: Design, synthesis and biological evaluation.
    Rizk OH, Teleb M, Abu-Serie MM, Shaaban OG.
    Bioorg Chem; 2019 Nov 10; 92():103189. PubMed ID: 31473473
    [Abstract] [Full Text] [Related]

  • 16. Design, synthesis, cytotoxicity screening and molecular docking of new 3-cyanopyridines as survivin inhibitors and apoptosis inducers.
    Sabour R, Harras MF, Mehany ABM.
    Bioorg Chem; 2020 Jan 10; 94():103358. PubMed ID: 31679838
    [Abstract] [Full Text] [Related]

  • 17. Discovery of PIM-1 kinase inhibitors based on the 2,5-disubstituted 1,3,4-oxadiazole scaffold against prostate cancer: Design, synthesis, in vitro and in vivo cytotoxicity investigation.
    Castanet AS, Nafie MS, Said SA, Arafa RK.
    Eur J Med Chem; 2023 Mar 15; 250():115220. PubMed ID: 36848846
    [Abstract] [Full Text] [Related]

  • 18. Structural optimization of 4-(imidazol-5-yl)pyridine derivatives affords broad-spectrum anticancer agents with selective B-RAFV600E/p38α kinase inhibitory activity: Synthesis, in vitro assays and in silico study.
    Ali EMH, Mersal KI, Ammar UM, Zaraei SO, Abdel-Maksoud MS, El-Gamal MI, Haque MM, Das T, Kim EE, Lee JS, Lee KH, Kim HK, Oh CH.
    Eur J Pharm Sci; 2022 Apr 01; 171():106115. PubMed ID: 34995782
    [Abstract] [Full Text] [Related]

  • 19. Design and molecular modeling of novel P38α MAPK inhibitors targeting breast cancer, synthesized from oxygen heterocyclic natural compounds.
    Abdelhafez OM, Ahmed EY, Abdel Latif NA, Arafa RK, Abd Elmageed ZY, Ali HI.
    Bioorg Med Chem; 2019 Apr 01; 27(7):1308-1319. PubMed ID: 30792101
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and anticancer activity of some pyrido[2,3-d]pyrimidine derivatives as apoptosis inducers and cyclin-dependent kinase inhibitors.
    Abbas SE, George RF, Samir EM, Aref MM, Abdel-Aziz HA.
    Future Med Chem; 2019 Sep 01; 11(18):2395-2414. PubMed ID: 31544523
    [Abstract] [Full Text] [Related]

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