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PUBMED FOR HANDHELDS

Journal Abstract Search


630 related items for PubMed ID: 31838287

  • 1. New phosphazine and phosphazide derivatives as multifunctional ligands targeting acetylcholinesterase and β-Amyloid aggregation for treatment of Alzheimer's disease.
    El-Sayed NF, El-Hussieny M, Ewies EF, Fouad MA, Boulos LS.
    Bioorg Chem; 2020 Jan; 95():103499. PubMed ID: 31838287
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis, in-silico and biological evaluation of novel chalcone-O-carbamate derivatives as multifunctional agents for the treatment of Alzheimer's disease.
    Sang Z, Wang K, Shi J, Liu W, Tan Z.
    Eur J Med Chem; 2019 Sep 15; 178():726-739. PubMed ID: 31229875
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis, and biological evaluation of ferulic acid based 1,3,4-oxadiazole hybrids as multifunctional therapeutics for the treatment of Alzheimer's disease.
    Tripathi A, Choubey PK, Sharma P, Seth A, Saraf P, Shrivastava SK.
    Bioorg Chem; 2020 Jan 15; 95():103506. PubMed ID: 31887472
    [Abstract] [Full Text] [Related]

  • 4. Novel chromanone-dithiocarbamate hybrids as multifunctional AChE inhibitors with β-amyloid anti-aggregation properties for the treatment of Alzheimer's disease.
    Jiang N, Ding J, Liu J, Sun X, Zhang Z, Mo Z, Li X, Yin H, Tang W, Xie SS.
    Bioorg Chem; 2019 Aug 15; 89():103027. PubMed ID: 31176237
    [Abstract] [Full Text] [Related]

  • 5. Design, synthesis and biological evaluation of new coumarin-dithiocarbamate hybrids as multifunctional agents for the treatment of Alzheimer's disease.
    Jiang N, Huang Q, Liu J, Liang N, Li Q, Li Q, Xie SS.
    Eur J Med Chem; 2018 Feb 25; 146():287-298. PubMed ID: 29407958
    [Abstract] [Full Text] [Related]

  • 6. Discovery of novel series of 2-substituted benzo[d]oxazol-5-amine derivatives as multi-target directed ligands for the treatment of Alzheimer's disease.
    Gutti G, Kakarla R, Kumar D, Beohar M, Ganeshpurkar A, Kumar A, Krishnamurthy S, Singh SK.
    Eur J Med Chem; 2019 Nov 15; 182():111613. PubMed ID: 31437780
    [Abstract] [Full Text] [Related]

  • 7. New coumarin-benzotriazole based hybrid molecules as inhibitors of acetylcholinesterase and amyloid aggregation.
    Singh A, Sharma S, Arora S, Attri S, Kaur P, Kaur Gulati H, Bhagat K, Kumar N, Singh H, Vir Singh J, Mohinder Singh Bedi P.
    Bioorg Med Chem Lett; 2020 Oct 15; 30(20):127477. PubMed ID: 32781220
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis and biological activity of novel tacrine-isatin Schiff base hybrid derivatives.
    Riazimontazer E, Sadeghpour H, Nadri H, Sakhteman A, Tüylü Küçükkılınç T, Miri R, Edraki N.
    Bioorg Chem; 2019 Aug 15; 89():103006. PubMed ID: 31158577
    [Abstract] [Full Text] [Related]

  • 9. Biological evaluation of synthetic α,β-unsaturated carbonyl based cyclohexanone derivatives as neuroprotective novel inhibitors of acetylcholinesterase, butyrylcholinesterase and amyloid-β aggregation.
    Zha GF, Zhang CP, Qin HL, Jantan I, Sher M, Amjad MW, Hussain MA, Hussain Z, Bukhari SN.
    Bioorg Med Chem; 2016 May 15; 24(10):2352-9. PubMed ID: 27083471
    [Abstract] [Full Text] [Related]

  • 10. Design, synthesis and biological activity of novel donepezil derivatives bearing N-benzyl pyridinium moiety as potent and dual binding site acetylcholinesterase inhibitors.
    Lan JS, Zhang T, Liu Y, Yang J, Xie SS, Liu J, Miao ZY, Ding Y.
    Eur J Med Chem; 2017 Jun 16; 133():184-196. PubMed ID: 28388521
    [Abstract] [Full Text] [Related]

  • 11. Novel deoxyvasicinone and tetrahydro-beta-carboline hybrids as inhibitors of acetylcholinesterase and amyloid beta aggregation.
    Du H, Jiang X, Ma M, Xu H, Liu S, Ma F.
    Bioorg Med Chem Lett; 2020 Dec 15; 30(24):127659. PubMed ID: 33137375
    [Abstract] [Full Text] [Related]

  • 12. Rational modification of donepezil as multifunctional acetylcholinesterase inhibitors for the treatment of Alzheimer's disease.
    Wang ZM, Cai P, Liu QH, Xu DQ, Yang XL, Wu JJ, Kong LY, Wang XB.
    Eur J Med Chem; 2016 Nov 10; 123():282-297. PubMed ID: 27484514
    [Abstract] [Full Text] [Related]

  • 13. Synthesis, pharmacology and molecular docking on multifunctional tacrine-ferulic acid hybrids as cholinesterase inhibitors against Alzheimer's disease.
    Zhu J, Yang H, Chen Y, Lin H, Li Q, Mo J, Bian Y, Pei Y, Sun H.
    J Enzyme Inhib Med Chem; 2018 Dec 10; 33(1):496-506. PubMed ID: 29405075
    [Abstract] [Full Text] [Related]

  • 14. Novel deoxyvasicinone derivatives as potent multitarget-directed ligands for the treatment of Alzheimer's disease: Design, synthesis, and biological evaluation.
    Ma F, Du H.
    Eur J Med Chem; 2017 Nov 10; 140():118-127. PubMed ID: 28923380
    [Abstract] [Full Text] [Related]

  • 15. Synthesis of new N-benzylpiperidine derivatives as cholinesterase inhibitors with β-amyloid anti-aggregation properties and beneficial effects on memory in vivo.
    Więckowska A, Więckowski K, Bajda M, Brus B, Sałat K, Czerwińska P, Gobec S, Filipek B, Malawska B.
    Bioorg Med Chem; 2015 May 15; 23(10):2445-57. PubMed ID: 25868744
    [Abstract] [Full Text] [Related]

  • 16. Novel 3-benzylidene/benzylphthalide Mannich base derivatives as potential multifunctional agents for the treatment of Alzheimer's disease.
    Cao Z, Song Q, Yu G, Liu Z, Cong S, Tan Z, Deng Y.
    Bioorg Med Chem; 2021 Apr 01; 35():116074. PubMed ID: 33640707
    [Abstract] [Full Text] [Related]

  • 17. Tetrahydroacridine derivatives with dichloronicotinic acid moiety as attractive, multipotent agents for Alzheimer's disease treatment.
    Czarnecka K, Chufarova N, Halczuk K, Maciejewska K, Girek M, Skibiński R, Jończyk J, Bajda M, Kabziński J, Majsterek I, Szymański P.
    Eur J Med Chem; 2018 Feb 10; 145():760-769. PubMed ID: 29353726
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis, and multitargeted profiling of N-benzylpyrrolidine derivatives for the treatment of Alzheimer's disease.
    Choubey PK, Tripathi A, Sharma P, Shrivastava SK.
    Bioorg Med Chem; 2020 Nov 15; 28(22):115721. PubMed ID: 33007563
    [Abstract] [Full Text] [Related]

  • 19. Design, synthesis and evaluation of scutellarein-O-alkylamines as multifunctional agents for the treatment of Alzheimer's disease.
    Sang Z, Qiang X, Li Y, Yuan W, Liu Q, Shi Y, Ang W, Luo Y, Tan Z, Deng Y.
    Eur J Med Chem; 2015 Apr 13; 94():348-66. PubMed ID: 25778991
    [Abstract] [Full Text] [Related]

  • 20. Tacrine-hydroxamate derivatives as multitarget-directed ligands for the treatment of Alzheimer's disease: Design, synthesis, and biological evaluation.
    Xu A, He F, Zhang X, Li X, Ran Y, Wei C, James Chou C, Zhang R, Wu J.
    Bioorg Chem; 2020 May 13; 98():103721. PubMed ID: 32193030
    [Abstract] [Full Text] [Related]


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