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Journal Abstract Search

469 related items for PubMed ID: 31880912

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  • 5. 3-Hydroxypyrimidine-2,4-diones as Selective Active Site Inhibitors of HIV Reverse Transcriptase-Associated RNase H: Design, Synthesis, and Biochemical Evaluations.
    Tang J, Liu F, Nagy E, Miller L, Kirby KA, Wilson DJ, Wu B, Sarafianos SG, Parniak MA, Wang Z.
    J Med Chem; 2016 Mar 24; 59(6):2648-59. PubMed ID: 26927866
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  • 6. Pharmacophore-based design of novel 3-hydroxypyrimidine-2,4-dione subtypes as inhibitors of HIV reverse transcriptase-associated RNase H: Tolerance of a nonflexible linker.
    Tang J, Do HT, Huber AD, Casey MC, Kirby KA, Wilson DJ, Kankanala J, Parniak MA, Sarafianos SG, Wang Z.
    Eur J Med Chem; 2019 Mar 15; 166():390-399. PubMed ID: 30739822
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  • 8. Design, synthesis, biochemical, and antiviral evaluations of C6 benzyl and C6 biarylmethyl substituted 2-hydroxylisoquinoline-1,3-diones: dual inhibition against HIV reverse transcriptase-associated RNase H and polymerase with antiviral activities.
    Vernekar SK, Liu Z, Nagy E, Miller L, Kirby KA, Wilson DJ, Kankanala J, Sarafianos SG, Parniak MA, Wang Z.
    J Med Chem; 2015 Jan 22; 58(2):651-64. PubMed ID: 25522204
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  • 9. Design, Synthesis, and Biological Evaluations of Hydroxypyridonecarboxylic Acids as Inhibitors of HIV Reverse Transcriptase Associated RNase H.
    Kankanala J, Kirby KA, Liu F, Miller L, Nagy E, Wilson DJ, Parniak MA, Sarafianos SG, Wang Z.
    J Med Chem; 2016 May 26; 59(10):5051-62. PubMed ID: 27094954
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  • 11. Developing and Evaluating Inhibitors against the RNase H Active Site of HIV-1 Reverse Transcriptase.
    Boyer PL, Smith SJ, Zhao XZ, Das K, Gruber K, Arnold E, Burke TR, Hughes SH.
    J Virol; 2018 Jul 01; 92(13):. PubMed ID: 29643235
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  • 12. Ribonuclease H/DNA Polymerase HIV-1 Reverse Transcriptase Dual Inhibitor: Mechanistic Studies on the Allosteric Mode of Action of Isatin-Based Compound RMNC6.
    Corona A, Meleddu R, Esposito F, Distinto S, Bianco G, Masaoka T, Maccioni E, Menéndez-Arias L, Alcaro S, Le Grice SF, Tramontano E.
    PLoS One; 2016 Jul 01; 11(1):e0147225. PubMed ID: 26800261
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  • 14. Structural basis for the inhibition of RNase H activity of HIV-1 reverse transcriptase by RNase H active site-directed inhibitors.
    Su HP, Yan Y, Prasad GS, Smith RF, Daniels CL, Abeywickrema PD, Reid JC, Loughran HM, Kornienko M, Sharma S, Grobler JA, Xu B, Sardana V, Allison TJ, Williams PD, Darke PL, Hazuda DJ, Munshi S.
    J Virol; 2010 Aug 01; 84(15):7625-33. PubMed ID: 20484498
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  • 15. Discovery, optimization, and target identification of novel coumarin derivatives as HIV-1 reverse transcriptase-associated ribonuclease H inhibitors.
    Kang D, Urhan Ç, Wei F, Frutos-Beltrán E, Sun L, Álvarez M, Feng D, Tao Y, Pannecouque C, De Clercq E, Menéndez-Arias L, Liu X, Zhan P.
    Eur J Med Chem; 2021 Dec 05; 225():113769. PubMed ID: 34403976
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  • 16. Dissecting the effects of DNA polymerase and ribonuclease H inhibitor combinations on HIV-1 reverse-transcriptase activities.
    Shaw-Reid CA, Feuston B, Munshi V, Getty K, Krueger J, Hazuda DJ, Parniak MA, Miller MD, Lewis D.
    Biochemistry; 2005 Feb 08; 44(5):1595-606. PubMed ID: 15683243
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  • 19. Molecular Docking and Molecular Dynamics Simulation Based Approach to Explore the Dual Inhibitor Against HIV-1 Reverse Transcriptase and Integrase.
    Chander S, Pandey RK, Penta A, Choudhary BS, Sharma M, Malik R, Prajapati VK, Murugesan S.
    Comb Chem High Throughput Screen; 2017 Feb 08; 20(8):734-746. PubMed ID: 28641512
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  • 20. Synthesis, activity, and structural analysis of novel α-hydroxytropolone inhibitors of human immunodeficiency virus reverse transcriptase-associated ribonuclease H.
    Chung S, Himmel DM, Jiang JK, Wojtak K, Bauman JD, Rausch JW, Wilson JA, Beutler JA, Thomas CJ, Arnold E, Le Grice SF.
    J Med Chem; 2011 Jul 14; 54(13):4462-73. PubMed ID: 21568335
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