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204 related items for PubMed ID: 31894340

  • 1. Tanshinone IIA enhances the inhibitory effect of imatinib on proliferation and motility of acute leukemia cell line TIB‑152 in vivo and in vitro by inhibiting the PI3K/AKT/mTOR signaling pathway.
    Teng Z, Xu S, Lei Q.
    Oncol Rep; 2020 Feb; 43(2):503-515. PubMed ID: 31894340
    [Abstract] [Full Text] [Related]

  • 2. Tanshinone IIA affects the malignant growth of Cholangiocarcinoma cells by inhibiting the PI3K-Akt-mTOR pathway.
    Liu H, Liu C, Wang M, Sun D, Zhu P, Zhang P, Tan X, Shi G.
    Sci Rep; 2021 Sep 29; 11(1):19268. PubMed ID: 34588580
    [Abstract] [Full Text] [Related]

  • 3. Tanshinone I attenuates the malignant biological properties of ovarian cancer by inducing apoptosis and autophagy via the inactivation of PI3K/AKT/mTOR pathway.
    Zhou J, Jiang YY, Chen H, Wu YC, Zhang L.
    Cell Prolif; 2020 Feb 29; 53(2):e12739. PubMed ID: 31820522
    [Abstract] [Full Text] [Related]

  • 4. Nutlin-3 plus tanshinone IIA exhibits synergetic anti-leukemia effect with imatinib by reactivating p53 and inhibiting the AKT/mTOR pathway in Ph+ ALL.
    Guo Y, Li Y, Xiang B, Huang XO, Ma HB, Wang FF, Gong YP.
    Biochem J; 2017 Dec 06; 474(24):4153-4170. PubMed ID: 29046392
    [Abstract] [Full Text] [Related]

  • 5. Regulation of the cell cycle and PI3K/Akt/mTOR signaling pathway by tanshinone I in human breast cancer cell lines.
    Wang L, Wu J, Lu J, Ma R, Sun D, Tang J.
    Mol Med Rep; 2015 Feb 06; 11(2):931-9. PubMed ID: 25355053
    [Abstract] [Full Text] [Related]

  • 6. Oridonin in combination with imatinib exerts synergetic anti-leukemia effect in Ph+ acute lymphoblastic leukemia cells in vitro by inhibiting activation of LYN/mTOR signaling pathway.
    Guo Y, Shan Q, Gong Y, Lin J, Yang X, Zhou R.
    Cancer Biol Ther; 2012 Nov 06; 13(13):1244-54. PubMed ID: 22895079
    [Abstract] [Full Text] [Related]

  • 7. The antitumor natural product tanshinone IIA inhibits protein kinase C and acts synergistically with 17-AAG.
    Lv C, Zeng HW, Wang JX, Yuan X, Zhang C, Fang T, Yang PM, Wu T, Zhou YD, Nagle DG, Zhang WD.
    Cell Death Dis; 2018 Feb 07; 9(2):165. PubMed ID: 29416003
    [Abstract] [Full Text] [Related]

  • 8. Tanshinone IIA inhibits proliferation and migration by downregulation of the PI3K/Akt pathway in small cell lung cancer cells.
    Jiang Y, Bi Y, Zhou L, Zheng S, Jian T, Chen J.
    BMC Complement Med Ther; 2024 Jan 31; 24(1):68. PubMed ID: 38297301
    [Abstract] [Full Text] [Related]

  • 9. [The Mechanism of Combination using mTORC1/2 Inhibitor and Imatinib to Suppress Cell Proliferation of Ph +ALL Cell Line].
    Wu JH, Shi FF, Gong YP, Shi R.
    Sichuan Da Xue Xue Bao Yi Xue Ban; 2017 Mar 31; 48(2):216-220. PubMed ID: 28612529
    [Abstract] [Full Text] [Related]

  • 10. Tanshinone IIA decreases the protein expression of EGFR, and IGFR blocking the PI3K/Akt/mTOR pathway in gastric carcinoma AGS cells both in vitro and in vivo.
    Su CC, Chiu TL.
    Oncol Rep; 2016 Aug 31; 36(2):1173-9. PubMed ID: 27277844
    [Abstract] [Full Text] [Related]

  • 11. Tanshinone IIA inhibits glucose metabolism leading to apoptosis in cervical cancer.
    Liu Z, Zhu W, Kong X, Chen X, Sun X, Zhang W, Zhang R.
    Oncol Rep; 2019 Nov 31; 42(5):1893-1903. PubMed ID: 31485631
    [Abstract] [Full Text] [Related]

  • 12. Tanshinone IIA Affects Autophagy and Apoptosis of Glioma Cells by Inhibiting Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin Signaling Pathway.
    Ding L, Ding L, Wang S, Wang S, Wang W, Wang W, Lv P, Lv P, Zhao D, Zhao D, Chen F, Chen F, Meng T, Meng T, Dong L, Dong L, Qi L, Qi L.
    Pharmacology; 2017 Nov 31; 99(3-4):188-195. PubMed ID: 27889779
    [Abstract] [Full Text] [Related]

  • 13. Efficacy of the dual PI3K and mTOR inhibitor NVP-BEZ235 in combination with imatinib mesylate against chronic myelogenous leukemia cell lines.
    Xin P, Li C, Zheng Y, Peng Q, Xiao H, Huang Y, Zhu X.
    Drug Des Devel Ther; 2017 Nov 31; 11():1115-1126. PubMed ID: 28435223
    [Abstract] [Full Text] [Related]

  • 14. Synergistic effects of selective inhibitors targeting the PI3K/AKT/mTOR pathway or NUP214-ABL1 fusion protein in human Acute Lymphoblastic Leukemia.
    Simioni C, Ultimo S, Martelli AM, Zauli G, Milani D, McCubrey JA, Capitani S, Neri LM.
    Oncotarget; 2016 Nov 29; 7(48):79842-79853. PubMed ID: 27821800
    [Abstract] [Full Text] [Related]

  • 15. Tanshinone IIA protects against myocardial ischemia reperfusion injury by activating the PI3K/Akt/mTOR signaling pathway.
    Li Q, Shen L, Wang Z, Jiang HP, Liu LX.
    Biomed Pharmacother; 2016 Dec 29; 84():106-114. PubMed ID: 27643552
    [Abstract] [Full Text] [Related]

  • 16. Ribavirin Inhibits the Activity of mTOR/eIF4E, ERK/Mnk1/eIF4E Signaling Pathway and Synergizes with Tyrosine Kinase Inhibitor Imatinib to Impair Bcr-Abl Mediated Proliferation and Apoptosis in Ph+ Leukemia.
    Shi F, Len Y, Gong Y, Shi R, Yang X, Naren D, Yan T.
    PLoS One; 2015 Dec 29; 10(8):e0136746. PubMed ID: 26317515
    [Abstract] [Full Text] [Related]

  • 17. Antiproliferative Activity of Carnosic Acid is Mediated via Inhibition of Cell Migration and Invasion, and Suppression of Phosphatidylinositol 3-Kinases (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Signaling Pathway.
    Zhao L, Zhang J, Fan Y, Li Y.
    Med Sci Monit; 2019 Oct 21; 25():7864-7871. PubMed ID: 31631173
    [Abstract] [Full Text] [Related]

  • 18. Mechanisms of Tanshinone II a inhibits malignant melanoma development through blocking autophagy signal transduction in A375 cell.
    Li X, Li Z, Li X, Liu B, Liu Z.
    BMC Cancer; 2017 May 22; 17(1):357. PubMed ID: 28532456
    [Abstract] [Full Text] [Related]

  • 19. Tanshinone IIA derivatives induced S-phase arrest through stabilizing c-myc G-quadruplex DNA to regulate ROS-mediated PI3K/Akt/mTOR pathway.
    Wang T, Zou J, Wu Q, Wang R, Yuan CL, Shu J, Zhai BB, Huang XT, Liu NZ, Hua FY, Wang XC, Mei WJ.
    Eur J Pharmacol; 2021 Dec 05; 912():174586. PubMed ID: 34710368
    [Abstract] [Full Text] [Related]

  • 20. Tanshinone IIA alleviates acute ethanol-induced myocardial apoptosis mainly through inhibiting the expression of PDCD4 and activating the PI3K/Akt pathway.
    Deng H, Yu B, Li Y.
    Phytother Res; 2021 Aug 05; 35(8):4309-4323. PubMed ID: 34169595
    [Abstract] [Full Text] [Related]

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