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Journal Abstract Search

243 related items for PubMed ID: 31900865

  • 1. Depending on the stress, histone deacetylase inhibitors act as heat shock protein co-inducers in motor neurons and potentiate arimoclomol, exerting neuroprotection through multiple mechanisms in ALS models.
    Kuta R, Larochelle N, Fernandez M, Pal A, Minotti S, Tibshirani M, St Louis K, Gentil BJ, Nalbantoglu JN, Hermann A, Durham HD.
    Cell Stress Chaperones; 2020 Jan; 25(1):173-191. PubMed ID: 31900865
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  • 2. Impact of histone deacetylase inhibition and arimoclomol on heat shock protein expression and disease biomarkers in primary culture models of familial ALS.
    Fernández Comaduran M, Minotti S, Jacob-Tomas S, Rizwan J, Larochelle N, Robitaille R, Sephton CF, Vera M, Nalbantoglu JN, Durham HD.
    Cell Stress Chaperones; 2024 Jun; 29(3):359-380. PubMed ID: 38570009
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  • 3. Reversal of cognitive deficits in FUSR521G amyotrophic lateral sclerosis mice by arimoclomol and a class I histone deacetylase inhibitor independent of heat shock protein induction.
    Pelaez MC, Fiore F, Larochelle N, Dabbaghizadeh A, Comaduran MF, Arbour D, Minotti S, Marcadet L, Semaan M, Robitaille R, Nalbantoglu JN, Sephton CF, Durham HD.
    Neurotherapeutics; 2024 Sep; 21(5):e00388. PubMed ID: 38972779
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  • 4. The role of heat shock proteins in Amyotrophic Lateral Sclerosis: The therapeutic potential of Arimoclomol.
    Kalmar B, Lu CH, Greensmith L.
    Pharmacol Ther; 2014 Jan; 141(1):40-54. PubMed ID: 23978556
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  • 6. Arimoclomol, a coinducer of heat shock proteins for the potential treatment of amyotrophic lateral sclerosis.
    Phukan J.
    IDrugs; 2010 Jul; 13(7):482-96. PubMed ID: 20582873
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  • 7. High threshold for induction of the stress response in motor neurons is associated with failure to activate HSF1.
    Batulan Z, Shinder GA, Minotti S, He BP, Doroudchi MM, Nalbantoglu J, Strong MJ, Durham HD.
    J Neurosci; 2003 Jul 02; 23(13):5789-98. PubMed ID: 12843283
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  • 9. Nonsteroidal anti-inflammatory drugs differentially affect the heat shock response in cultured spinal cord cells.
    Batulan Z, Nalbantoglu J, Durham HD.
    Cell Stress Chaperones; 2005 Jul 02; 10(3):185-96. PubMed ID: 16184763
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  • 10. A novel small molecule HSP90 inhibitor, NXD30001, differentially induces heat shock proteins in nervous tissue in culture and in vivo.
    Cha JR, St Louis KJ, Tradewell ML, Gentil BJ, Minotti S, Jaffer ZM, Chen R, Rubenstein AE, Durham HD.
    Cell Stress Chaperones; 2014 May 02; 19(3):421-35. PubMed ID: 24092395
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  • 13. Expression of the protein chaperone, clusterin, in spinal cord cells constitutively and following cellular stress, and upregulation by treatment with Hsp90 inhibitor.
    Zinkie S, Gentil BJ, Minotti S, Durham HD.
    Cell Stress Chaperones; 2013 Nov 02; 18(6):745-58. PubMed ID: 23595219
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  • 15. Characterizing the role of Hsp90 in production of heat shock proteins in motor neurons reveals a suppressive effect of wild-type Hsf1.
    Taylor DM, Tradewell ML, Minotti S, Durham HD.
    Cell Stress Chaperones; 2007 Nov 02; 12(2):151-62. PubMed ID: 17688194
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  • 16. Treatment with a coinducer of the heat shock response delays muscle denervation in the SOD1-G93A mouse model of amyotrophic lateral sclerosis.
    Kalmar B, Edet-Amana E, Greensmith L.
    Amyotroph Lateral Scler; 2012 Jun 02; 13(4):378-92. PubMed ID: 22591194
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  • 17. Knockdown of Heat Shock Proteins HSPA6 (Hsp70B') and HSPA1A (Hsp70-1) Sensitizes Differentiated Human Neuronal Cells to Cellular Stress.
    Deane CAS, Brown IR.
    Neurochem Res; 2018 Feb 02; 43(2):340-350. PubMed ID: 29090408
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  • 20. Activation of the heat shock response in a primary cellular model of motoneuron neurodegeneration-evidence for neuroprotective and neurotoxic effects.
    Kalmar B, Greensmith L.
    Cell Mol Biol Lett; 2009 Feb 02; 14(2):319-35. PubMed ID: 19183864
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