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Journal Abstract Search

337 related items for PubMed ID: 31967309

  • 1. CP-25 inhibits PGE2-induced angiogenesis by down-regulating EP4/AC/cAMP/PKA-mediated GRK2 translocation.
    Han CC, Liu Q, Zhang Y, Li YF, Cui DQ, Luo TT, Zhang YW, Wang XM, Wang C, Ma Y, Wei W.
    Clin Sci (Lond); 2020 Feb 14; 134(3):331-347. PubMed ID: 31967309
    [Abstract] [Full Text] [Related]

  • 2. GRK2 Mediated Abnormal Transduction of PGE2-EP4-cAMP-CREB Signaling Induces the Imbalance of Macrophages Polarization in Collagen-Induced Arthritis Mice.
    Yang X, Li S, Zhao Y, Li S, Zhao T, Tai Y, Zhang B, Wang X, Wang C, Chen J, Wang Q, Zhang L, Xu D, Chang Y, Wei W.
    Cells; 2019 Dec 08; 8(12):. PubMed ID: 31818003
    [Abstract] [Full Text] [Related]

  • 3. CP-25 reverses prostaglandin E4 receptor desensitization-induced fibroblast-like synoviocyte dysfunction via the G protein-coupled receptor kinase 2 in autoimmune arthritis.
    Jia XY, Chang Y, Wei F, Dai X, Wu YJ, Sun XJ, Xu S, Wu HX, Wang C, Yang XZ, Wei W.
    Acta Pharmacol Sin; 2019 Aug 08; 40(8):1029-1039. PubMed ID: 30643209
    [Abstract] [Full Text] [Related]

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  • 5. CP-25 exerts anti-angiogenic effects on a rat model of adjuvant-induced arthritis by promoting GRK2-induced downregulation of CXCR4-ERK1/2 signaling in endothelial cells.
    Zhang M, Gao M, Chen J, Song L, Wei W.
    Mol Med Rep; 2019 Dec 08; 20(6):4831-4842. PubMed ID: 31661133
    [Abstract] [Full Text] [Related]

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  • 7. Prostaglandin E2 receptor EP4 is involved in the cell growth and invasion of prostate cancer via the cAMP‑PKA/PI3K‑Akt signaling pathway.
    Xu S, Zhou W, Ge J, Zhang Z.
    Mol Med Rep; 2018 Mar 08; 17(3):4702-4712. PubMed ID: 29328471
    [Abstract] [Full Text] [Related]

  • 8. Paeoniflorin inhibits proliferation of fibroblast-like synoviocytes through suppressing G-protein-coupled receptor kinase 2.
    Chen JY, Wu HX, Chen Y, Zhang LL, Wang QT, Sun WY, Wei W.
    Planta Med; 2012 May 08; 78(7):665-71. PubMed ID: 22411721
    [Abstract] [Full Text] [Related]

  • 9. Paeoniflorin-6'-O-benzene sulfonate down-regulates CXCR4-Gβγ-PI3K/AKT mediated migration in fibroblast-like synoviocytes of rheumatoid arthritis by inhibiting GRK2 translocation.
    Wang DD, Jiang MY, Wang W, Zhou WJ, Zhang YW, Yang M, Chen JY, Wei W.
    Biochem Biophys Res Commun; 2020 Jun 04; 526(3):805-812. PubMed ID: 32268958
    [Abstract] [Full Text] [Related]

  • 10. Paeoniflorin inhibits function of synoviocytes pretreated by rIL-1α and regulates EP4 receptor expression.
    Chang Y, Zhang L, Wang C, Jia XY, Wei W.
    J Ethnopharmacol; 2011 Oct 11; 137(3):1275-82. PubMed ID: 21840386
    [Abstract] [Full Text] [Related]

  • 11. Prostaglandin E2 stimulates angiogenesis by activating the nitric oxide/cGMP pathway in human umbilical vein endothelial cells.
    Namkoong S, Lee SJ, Kim CK, Kim YM, Chung HT, Lee H, Han JA, Ha KS, Kwon YG, Kim YM.
    Exp Mol Med; 2005 Dec 31; 37(6):588-600. PubMed ID: 16391520
    [Abstract] [Full Text] [Related]

  • 12. Targeted inhibition of GRK2 kinase domain by CP-25 to reverse fibroblast-like synoviocytes dysfunction and improve collagen-induced arthritis in rats.
    Han C, Li Y, Zhang Y, Wang Y, Cui D, Luo T, Zhang Y, Liu Q, Li H, Wang C, Xu D, Ma Y, Wei W.
    Acta Pharm Sin B; 2021 Jul 31; 11(7):1835-1852. PubMed ID: 34386323
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  • 14. Paeoniflorin-6'O-benzene sulfonate suppresses fibroblast-like synoviocytes proliferation and migration in rheumatoid arthritis through regulating GRK2-Gβγ interaction.
    Zhang Y, Yang X, Han C, Wang D, Ma Y, Wei W.
    Exp Ther Med; 2022 Aug 31; 24(2):523. PubMed ID: 35837026
    [Abstract] [Full Text] [Related]

  • 15. Paeoniflorin-6'-o-benzene sulfonate ameliorates the progression of adjuvant-induced arthritis by inhibiting the interaction between Ahr and GRK2 of fibroblast-like synoviocytes.
    Zhang BJ, Wang YY, Jia CY, Li SS, Wang XW, Xu Y, Chen AY, Xu HP, Wang C, Yang ZY, Wei W, Chang Y.
    Int Immunopharmacol; 2022 Jul 31; 108():108678. PubMed ID: 35364431
    [Abstract] [Full Text] [Related]

  • 16. Prostaglandin E2 Inhibits NLRP3 Inflammasome Activation through EP4 Receptor and Intracellular Cyclic AMP in Human Macrophages.
    Sokolowska M, Chen LY, Liu Y, Martinez-Anton A, Qi HY, Logun C, Alsaaty S, Park YH, Kastner DL, Chae JJ, Shelhamer JH.
    J Immunol; 2015 Jun 01; 194(11):5472-5487. PubMed ID: 25917098
    [Abstract] [Full Text] [Related]

  • 17. Prostaglandin E2-stimulated prostanoid EP4 receptors induce prolonged de novo prostaglandin E2 synthesis through biphasic phosphorylation of extracellular signal-regulated kinases mediated by activation of protein kinase A in HCA-7 human colon cancer cells.
    Fujino H, Seira N, Kurata N, Araki Y, Nakamura H, Regan JW, Murayama T.
    Eur J Pharmacol; 2015 Dec 05; 768():149-59. PubMed ID: 26518053
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  • 19. Prostaglandin E2 promotes the cell growth and invasive ability of hepatocellular carcinoma cells by upregulating c-Myc expression via EP4 receptor and the PKA signaling pathway.
    Xia S, Ma J, Bai X, Zhang H, Cheng S, Zhang M, Zhang L, Du M, Wang Y, Li H, Rong R, Shi F, Yang Q, Leng J.
    Oncol Rep; 2014 Oct 05; 32(4):1521-30. PubMed ID: 25109834
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