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422 related items for PubMed ID: 31972235

  • 1. Mice With Increased Numbers of Polyploid Hepatocytes Maintain Regenerative Capacity But Develop Fewer Hepatocellular Carcinomas Following Chronic Liver Injury.
    Lin YH, Zhang S, Zhu M, Lu T, Chen K, Wen Z, Wang S, Xiao G, Luo D, Jia Y, Li L, MacConmara M, Hoshida Y, Singal AG, Yopp A, Wang T, Zhu H.
    Gastroenterology; 2020 May; 158(6):1698-1712.e14. PubMed ID: 31972235
    [Abstract] [Full Text] [Related]

  • 2. Knockdown of Anillin Actin Binding Protein Blocks Cytokinesis in Hepatocytes and Reduces Liver Tumor Development in Mice Without Affecting Regeneration.
    Zhang S, Nguyen LH, Zhou K, Tu HC, Sehgal A, Nassour I, Li L, Gopal P, Goodman J, Singal AG, Yopp A, Zhang Y, Siegwart DJ, Zhu H.
    Gastroenterology; 2018 Apr; 154(5):1421-1434. PubMed ID: 29274368
    [Abstract] [Full Text] [Related]

  • 3. TREM-2 defends the liver against hepatocellular carcinoma through multifactorial protective mechanisms.
    Esparza-Baquer A, Labiano I, Sharif O, Agirre-Lizaso A, Oakley F, Rodrigues PM, Zhuravleva E, O'Rourke CJ, Hijona E, Jimenez-Agüero R, Riaño I, Landa A, La Casta A, Zaki MYW, Munoz-Garrido P, Azkargorta M, Elortza F, Vogel A, Schabbauer G, Aspichueta P, Andersen JB, Knapp S, Mann DA, Bujanda L, Banales JM, Perugorria MJ.
    Gut; 2021 Jul; 70(7):1345-1361. PubMed ID: 32907830
    [Abstract] [Full Text] [Related]

  • 4. Ccne1 Overexpression Causes Chromosome Instability in Liver Cells and Liver Tumor Development in Mice.
    Aziz K, Limzerwala JF, Sturmlechner I, Hurley E, Zhang C, Jeganathan KB, Nelson G, Bronk S, Fierro Velasco RO, van Deursen EJ, O'Brien DR, Kocher JA, Youssef SA, van Ree JH, de Bruin A, van den Bos H, Spierings DCJ, Foijer F, van de Sluis B, Roberts LR, Gores GJ, Li H, van Deursen JM.
    Gastroenterology; 2019 Jul; 157(1):210-226.e12. PubMed ID: 30878468
    [Abstract] [Full Text] [Related]

  • 5. Proliferative polyploid cells give rise to tumors via ploidy reduction.
    Matsumoto T, Wakefield L, Peters A, Peto M, Spellman P, Grompe M.
    Nat Commun; 2021 Jan 28; 12(1):646. PubMed ID: 33510149
    [Abstract] [Full Text] [Related]

  • 6. DNA ploidy and autophagic protein degradation as determinants of hepatocellular growth and survival.
    Seglen PO.
    Cell Biol Toxicol; 1997 Jul 28; 13(4-5):301-15. PubMed ID: 9298250
    [Abstract] [Full Text] [Related]

  • 7. NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice.
    Liang S, Ma HY, Zhong Z, Dhar D, Liu X, Xu J, Koyama Y, Nishio T, Karin D, Karin G, Mccubbin R, Zhang C, Hu R, Yang G, Chen L, Ganguly S, Lan T, Karin M, Kisseleva T, Brenner DA.
    Gastroenterology; 2019 Mar 28; 156(4):1156-1172.e6. PubMed ID: 30445007
    [Abstract] [Full Text] [Related]

  • 8. Aneuploidy, polyploidy and ploidy reversal in the liver.
    Duncan AW.
    Semin Cell Dev Biol; 2013 Apr 28; 24(4):347-56. PubMed ID: 23333793
    [Abstract] [Full Text] [Related]

  • 9. Implications of Polyploidy and Ploidy Alterations in Hepatocytes in Liver Injuries and Cancers.
    Matsumoto T.
    Int J Mol Sci; 2022 Aug 20; 23(16):. PubMed ID: 36012671
    [Abstract] [Full Text] [Related]

  • 10. Persistent hepatocyte apoptosis promotes tumorigenesis from diethylnitrosamine-transformed hepatocytes through increased oxidative stress, independent of compensatory liver regeneration.
    Nozaki Y, Hikita H, Tanaka S, Fukumoto K, Urabe M, Sato K, Myojin Y, Doi A, Murai K, Sakane S, Saito Y, Kodama T, Sakamori R, Tatsumi T, Takehara T.
    Sci Rep; 2021 Feb 09; 11(1):3363. PubMed ID: 33564095
    [Abstract] [Full Text] [Related]

  • 11. Tristetraprolin Promotes Hepatic Inflammation and Tumor Initiation but Restrains Cancer Progression to Malignancy.
    Dolicka D, Sobolewski C, Gjorgjieva M, Correia de Sousa M, Berthou F, De Vito C, Colin DJ, Bejuy O, Fournier M, Maeder C, Blackshear PJ, Rubbia-Brandt L, Foti M.
    Cell Mol Gastroenterol Hepatol; 2021 Feb 09; 11(2):597-621. PubMed ID: 32987153
    [Abstract] [Full Text] [Related]

  • 12. An Immune Gene Expression Signature Associated With Development of Human Hepatocellular Carcinoma Identifies Mice That Respond to Chemopreventive Agents.
    Moeini A, Torrecilla S, Tovar V, Montironi C, Andreu-Oller C, Peix J, Higuera M, Pfister D, Ramadori P, Pinyol R, Solé M, Heikenwälder M, Friedman SL, Sia D, Llovet JM.
    Gastroenterology; 2019 Nov 09; 157(5):1383-1397.e11. PubMed ID: 31344396
    [Abstract] [Full Text] [Related]

  • 13. The role of bone marrow-derived cells in the origin of liver cancer revealed by single-cell sequencing.
    Chen L, Yi X, Guo P, Guo H, Chen Z, Hou C, Qi L, Wang Y, Li C, Liu P, Liu Y, Xu Y, Zhang N.
    Cancer Biol Med; 2020 Feb 15; 17(1):142-153. PubMed ID: 32296582
    [Abstract] [Full Text] [Related]

  • 14. The Polyploid State Plays a Tumor-Suppressive Role in the Liver.
    Zhang S, Zhou K, Luo X, Li L, Tu HC, Sehgal A, Nguyen LH, Zhang Y, Gopal P, Tarlow BD, Siegwart DJ, Zhu H.
    Dev Cell; 2018 Feb 26; 44(4):447-459.e5. PubMed ID: 29429824
    [Abstract] [Full Text] [Related]

  • 15. Polyploid Hepatocytes Facilitate Adaptation and Regeneration to Chronic Liver Injury.
    Wilkinson PD, Alencastro F, Delgado ER, Leek MP, Weirich MP, Otero PA, Roy N, Brown WK, Oertel M, Duncan AW.
    Am J Pathol; 2019 Jun 26; 189(6):1241-1255. PubMed ID: 30928253
    [Abstract] [Full Text] [Related]

  • 16. The DEN and CCl4 -Induced Mouse Model of Fibrosis and Inflammation-Associated Hepatocellular Carcinoma.
    Uehara T, Pogribny IP, Rusyn I.
    Curr Protoc Pharmacol; 2014 Sep 02; 66():14.30.1-14.30.10. PubMed ID: 25181010
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of androgen/AR signaling inhibits diethylnitrosamine (DEN) induced tumour initiation and remodels liver immune cell networks.
    Helms TH, Mullins RD, Thomas-Ahner JM, Kulp SK, Campbell MJ, Lucas F, Schmidt N, LeMoine DM, Getaneh S, Xie Z, Phelps MA, Clinton SK, Coss CC.
    Sci Rep; 2021 Feb 11; 11(1):3646. PubMed ID: 33574348
    [Abstract] [Full Text] [Related]

  • 18. Reactive cholangiocytes differentiate into proliferative hepatocytes with efficient DNA repair in mice with chronic liver injury.
    Manco R, Clerbaux LA, Verhulst S, Bou Nader M, Sempoux C, Ambroise J, Bearzatto B, Gala JL, Horsmans Y, van Grunsven L, Desdouets C, Leclercq I.
    J Hepatol; 2019 Jun 11; 70(6):1180-1191. PubMed ID: 30794890
    [Abstract] [Full Text] [Related]

  • 19. STAT3 deficiency prevents hepatocarcinogenesis and promotes biliary proliferation in thioacetamide-induced liver injury.
    Abe M, Yoshida T, Akiba J, Ikezono Y, Wada F, Masuda A, Sakaue T, Tanaka T, Iwamoto H, Nakamura T, Sata M, Koga H, Yoshimura A, Torimura T.
    World J Gastroenterol; 2017 Oct 07; 23(37):6833-6844. PubMed ID: 29085226
    [Abstract] [Full Text] [Related]

  • 20. Hepatocyte ploidy in regenerating livers after partial hepatectomy, drug-induced necrosis, and cirrhosis.
    Gandillet A, Alexandre E, Royer C, Cinqualbre J, Jaeck D, Richert L.
    Eur Surg Res; 2003 Oct 07; 35(3):148-60. PubMed ID: 12740535
    [Abstract] [Full Text] [Related]

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