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Journal Abstract Search

224 related items for PubMed ID: 31974274

  • 1. Epitope and Fc-Mediated Cross-linking, but Not High Affinity, Are Critical for Antitumor Activity of CD137 Agonist Antibody with Reduced Liver Toxicity.
    Ho SK, Xu Z, Thakur A, Fox M, Tan SS, DiGiammarino E, Zhou L, Sho M, Cairns B, Zhao V, Xiong M, Samayoa J, Forsyth CM, Powers DB, Chao DT, Hollenbaugh D, Alvarez HM, Akamatsu Y.
    Mol Cancer Ther; 2020 Apr; 19(4):1040-1051. PubMed ID: 31974274
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  • 3. Differentiated agonistic antibody targeting CD137 eradicates large tumors without hepatotoxicity.
    Eskiocak U, Guzman W, Wolf B, Cummings C, Milling L, Wu HJ, Ophir M, Lambden C, Bakhru P, Gilmore DC, Ottinger S, Liu L, McConaughy WK, He SQ, Wang C, Leung CL, Lajoie J, Carson WF, Zizlsperger N, Schmidt MM, Anderson AC, Bobrowicz P, Schuetz TJ, Tighe R.
    JCI Insight; 2020 Mar 12; 5(5):. PubMed ID: 32161196
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  • 11. The emerging landscape of novel 4-1BB (CD137) agonistic drugs for cancer immunotherapy.
    Claus C, Ferrara-Koller C, Klein C.
    MAbs; 2023 Mar 12; 15(1):2167189. PubMed ID: 36727218
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  • 12. Treatment with anti-CD137 mAbs causes intense accumulations of liver T cells without selective antitumor immunotherapeutic effects in this organ.
    Dubrot J, Milheiro F, Alfaro C, Palazón A, Martinez-Forero I, Perez-Gracia JL, Morales-Kastresana A, Romero-Trevejo JL, Ochoa MC, Hervás-Stubbs S, Prieto J, Jure-Kunkel M, Chen L, Melero I.
    Cancer Immunol Immunother; 2010 Aug 12; 59(8):1223-33. PubMed ID: 20336294
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  • 17. A Multifunctional Role for Adjuvant Anti-4-1BB Therapy in Augmenting Antitumor Response by Chimeric Antigen Receptor T Cells.
    Mardiana S, John LB, Henderson MA, Slaney CY, von Scheidt B, Giuffrida L, Davenport AJ, Trapani JA, Neeson PJ, Loi S, Haynes NM, Kershaw MH, Beavis PA, Darcy PK.
    Cancer Res; 2017 Mar 15; 77(6):1296-1309. PubMed ID: 28082401
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  • 18. Antitumor efficacy and reduced toxicity using an anti-CD137 Probody therapeutic.
    Etxeberria I, Bolaños E, Teijeira A, Garasa S, Yanguas A, Azpilikueta A, Kavanaugh WM, Vasiljeva O, Belvin M, Howng B, Irving B, Tipton K, West J, Mei L, Korman AJ, Sega E, Olivera I, Cirella A, Ochoa MC, Rodriguez ME, Melero A, Sanmamed MF, Engelhardt JJ, Melero I.
    Proc Natl Acad Sci U S A; 2021 Jun 29; 118(26):. PubMed ID: 34172583
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  • 19. Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by Treg depletion.
    Houot R, Goldstein MJ, Kohrt HE, Myklebust JH, Alizadeh AA, Lin JT, Irish JM, Torchia JA, Kolstad A, Chen L, Levy R.
    Blood; 2009 Oct 15; 114(16):3431-8. PubMed ID: 19641184
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  • 20. CD1d-based combination therapy eradicates established tumors in mice.
    Teng MW, Sharkey J, McLaughlin NM, Exley MA, Smyth MJ.
    J Immunol; 2009 Aug 01; 183(3):1911-20. PubMed ID: 19620318
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