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Journal Abstract Search

161 related items for PubMed ID: 31974452

  • 1. Pifithrin-α alters p53 post-translational modifications pattern and differentially inhibits p53 target genes.
    Zhu J, Singh M, Selivanova G, Peuget S.
    Sci Rep; 2020 Jan 23; 10(1):1049. PubMed ID: 31974452
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  • 6. An evaluation of the ability of pifithrin-alpha and -beta to inhibit p53 function in two wild-type p53 human tumor cell lines.
    Walton MI, Wilson SC, Hardcastle IR, Mirza AR, Workman P.
    Mol Cancer Ther; 2005 Sep 23; 4(9):1369-77. PubMed ID: 16170029
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  • 7. Nutlin-3 induces HO-1 expression by activating JNK in a transcription-independent manner of p53.
    Choe YJ, Lee SY, Ko KW, Shin SJ, Kim HS.
    Int J Oncol; 2014 Mar 23; 44(3):761-8. PubMed ID: 24366007
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  • 8. P53 activation plays a crucial role in silibinin induced ROS generation via PUMA and JNK.
    Fan S, Qi M, Yu Y, Li L, Yao G, Tashiro S, Onodera S, Ikejima T.
    Free Radic Res; 2012 Mar 23; 46(3):310-9. PubMed ID: 22283740
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  • 11. P53 inhibitor pifithrin-α inhibits ropivacaine-induced neuronal apoptosis via the mitochondrial apoptosis pathway.
    Zeng L, Zhang F, Zhang Z, Xu M, Xu Y, Liu Y, Xu H, Sun X, Sang M, Luo H.
    J Biochem Mol Toxicol; 2021 Aug 23; 35(8):e22822. PubMed ID: 34091999
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  • 12. Activation of p53 by Nutlin-3a, an antagonist of MDM2, induces apoptosis and cellular senescence in adult T-cell leukemia cells.
    Hasegawa H, Yamada Y, Iha H, Tsukasaki K, Nagai K, Atogami S, Sugahara K, Tsuruda K, Ishizaki A, Kamihira S.
    Leukemia; 2009 Nov 23; 23(11):2090-101. PubMed ID: 19710698
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  • 13. Gambogic Acid Inhibits Malignant Melanoma Cell Proliferation Through Mitochondrial p66shc/ROS-p53/Bax-Mediated Apoptosis.
    Liang L, Zhang Z.
    Cell Physiol Biochem; 2016 Nov 23; 38(4):1618-30. PubMed ID: 27119348
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  • 14. Post-traumatic administration of the p53 inactivator pifithrin-α oxygen analogue reduces hippocampal neuronal loss and improves cognitive deficits after experimental traumatic brain injury.
    Yang LY, Greig NH, Huang YN, Hsieh TH, Tweedie D, Yu QS, Hoffer BJ, Luo Y, Kao YC, Wang JY.
    Neurobiol Dis; 2016 Dec 23; 96():216-226. PubMed ID: 27553877
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  • 15. Post-trauma administration of the pifithrin-α oxygen analog improves histological and functional outcomes after experimental traumatic brain injury.
    Yang LY, Chu YH, Tweedie D, Yu QS, Pick CG, Hoffer BJ, Greig NH, Wang JY.
    Exp Neurol; 2015 Jul 23; 269():56-66. PubMed ID: 25819102
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  • 16. The p53 inhibitor pifithrin-alpha is a potent agonist of the aryl hydrocarbon receptor.
    Hoagland MS, Hoagland EM, Swanson HI.
    J Pharmacol Exp Ther; 2005 Aug 23; 314(2):603-10. PubMed ID: 15843497
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  • 17. Differential protection and transactivation of P53, P21, Bcl2, PCNA, cyclin G, and MDM2 genes in rat liver and the HepG2 cell line upon exposure to pifithrin.
    Farah IO, Begum RA, Ishaque AB.
    Biomed Sci Instrum; 2007 Aug 23; 43():116-21. PubMed ID: 17487067
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  • 18. MDM2 inhibitor Nutlin-3a suppresses proliferation and promotes apoptosis in osteosarcoma cells.
    Wang B, Fang L, Zhao H, Xiang T, Wang D.
    Acta Biochim Biophys Sin (Shanghai); 2012 Aug 23; 44(8):685-91. PubMed ID: 22843172
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  • 19. Pivotal roles of p53 transcription-dependent and -independent pathways in manganese-induced mitochondrial dysfunction and neuronal apoptosis.
    Wan C, Ma X, Shi S, Zhao J, Nie X, Han J, Xiao J, Wang X, Jiang S, Jiang J.
    Toxicol Appl Pharmacol; 2014 Dec 15; 281(3):294-302. PubMed ID: 25448048
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  • 20. Pifithrin-alpha has a p53-independent cytoprotective effect on docosahexaenoic acid-induced cytotoxicity in human hepatocellular carcinoma HepG2 cells.
    Kanno S, Kurauchi K, Tomizawa A, Yomogida S, Ishikawa M.
    Toxicol Lett; 2015 Jan 22; 232(2):393-402. PubMed ID: 25448278
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