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Journal Abstract Search

149 related items for PubMed ID: 32005903

  • 1.
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  • 2. Activating Mutations in PAK1, Encoding p21-Activated Kinase 1, Cause a Neurodevelopmental Disorder.
    Harms FL, Kloth K, Bley A, Denecke J, Santer R, Lessel D, Hempel M, Kutsche K.
    Am J Hum Genet; 2018 Oct 04; 103(4):579-591. PubMed ID: 30290153
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  • 3. PAK1 c.1409 T > a (p. Leu470Gln) de novo variant affects the protein kinase domain, leading to epilepsy, macrocephaly, spastic quadriplegia, and hydrocephalus: Case report and review of the literature.
    Corriveau ML, Amaya SI, Koebel MC, Lerma VC, Michener SL, Turner A, Schultz RJ, Seto ES, Diaz-Medina GE, Craigen WJ, Swann JW, Xue M, Chao HT.
    Am J Med Genet A; 2023 Jun 04; 191(6):1619-1625. PubMed ID: 36905087
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  • 4. De novo variants in PAK1 lead to intellectual disability with macrocephaly and seizures.
    Horn S, Au M, Basel-Salmon L, Bayrak-Toydemir P, Chapin A, Cohen L, Elting MW, Graham JM, Gonzaga-Jauregui C, Konen O, Holzer M, Lemke J, Miller CE, Rey LK, Wolf NI, Weiss MM, Waisfisz Q, Mirzaa GM, Wieczorek D, Sticht H, Abou Jamra R.
    Brain; 2019 Nov 01; 142(11):3351-3359. PubMed ID: 31504246
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  • 6. The p21-activated kinase PAK3 forms heterodimers with PAK1 in brain implementing trans-regulation of PAK3 activity.
    Combeau G, Kreis P, Domenichini F, Amar M, Fossier P, Rousseau V, Barnier JV.
    J Biol Chem; 2012 Aug 31; 287(36):30084-96. PubMed ID: 22815483
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  • 10. Knockdown of PAK4 or PAK1 inhibits the proliferation of mutant KRAS colon cancer cells independently of RAF/MEK/ERK and PI3K/AKT signaling.
    Tabusa H, Brooks T, Massey AJ.
    Mol Cancer Res; 2013 Feb 31; 11(2):109-21. PubMed ID: 23233484
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  • 12. Autophosphorylation-dependent degradation of Pak1, triggered by the Rho-family GTPase, Chp.
    Weisz Hubsman M, Volinsky N, Manser E, Yablonski D, Aronheim A.
    Biochem J; 2007 Jun 15; 404(3):487-97. PubMed ID: 17355222
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  • 13. P21 activated kinase signaling in cancer.
    Rane CK, Minden A.
    Semin Cancer Biol; 2019 Feb 15; 54():40-49. PubMed ID: 29330094
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  • 15. Mechanism of activation of Pak1 kinase by membrane localization.
    Lu W, Mayer BJ.
    Oncogene; 1999 Jan 21; 18(3):797-806. PubMed ID: 9989831
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  • 16. Signaling, Regulation, and Specificity of the Type II p21-activated Kinases.
    Ha BH, Morse EM, Turk BE, Boggon TJ.
    J Biol Chem; 2015 May 22; 290(21):12975-83. PubMed ID: 25855792
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  • 17. [Mutations in the Effector Domain of RhoV GTPase Impair Its Binding to Pak1 Protein Kinase].
    Korobko IV, Shepelev MV.
    Mol Biol (Mosk); 2018 May 22; 52(4):692-698. PubMed ID: 30113035
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  • 18. Differential role for PAK1 and PAK4 during the invadopodia lifecycle.
    Nicholas NS, Pipili A, Lesjak MS, Wells CM.
    Small GTPases; 2019 Jul 22; 10(4):289-295. PubMed ID: 28301299
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  • 20. Functional and structural analyses of novel Smith-Kingsmore Syndrome-Associated MTOR variants reveal potential new mechanisms and predictors of pathogenicity.
    Besterman AD, Althoff T, Elfferich P, Gutierrez-Mejia I, Sadik J, Bernstein JA, van Ierland Y, Kattentidt-Mouravieva AA, Nellist M, Abramson J, Martinez-Agosto JA.
    PLoS Genet; 2021 Jul 22; 17(7):e1009651. PubMed ID: 34197453
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