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Journal Abstract Search

312 related items for PubMed ID: 32007269

  • 1. Stabilizing cardiac ryanodine receptor prevents the development of cardiac dysfunction and lethal arrhythmia in Ca2+/calmodulin-dependent protein kinase IIδc transgenic mice.
    Sufu-Shimizu Y, Okuda S, Kato T, Nishimura S, Uchinoumi H, Oda T, Kobayashi S, Yamamoto T, Yano M.
    Biochem Biophys Res Commun; 2020 Apr 02; 524(2):431-438. PubMed ID: 32007269
    [Abstract] [Full Text] [Related]

  • 2. CaMKII-mediated phosphorylation of RyR2 plays a crucial role in aberrant Ca2+ release as an arrhythmogenic substrate in cardiac troponin T-related familial hypertrophic cardiomyopathy.
    Okuda S, Sufu-Shimizu Y, Kato T, Fukuda M, Nishimura S, Oda T, Kobayashi S, Yamamoto T, Morimoto S, Yano M.
    Biochem Biophys Res Commun; 2018 Feb 19; 496(4):1250-1256. PubMed ID: 29402414
    [Abstract] [Full Text] [Related]

  • 3. Ca2+/calmodulin-dependent kinase IIδC-induced chronic heart failure does not depend on sarcoplasmic reticulum Ca2+ leak.
    Dewenter M, Seitz T, Steinbrecher JH, Westenbrink BD, Ling H, Lehnart SE, Wehrens XHT, Backs J, Brown JH, Maier LS, Neef S.
    ESC Heart Fail; 2024 Aug 19; 11(4):2191-2199. PubMed ID: 38616546
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  • 5. CaMKII-dependent phosphorylation of RyR2 promotes targetable pathological RyR2 conformational shift.
    Uchinoumi H, Yang Y, Oda T, Li N, Alsina KM, Puglisi JL, Chen-Izu Y, Cornea RL, Wehrens XHT, Bers DM.
    J Mol Cell Cardiol; 2016 Sep 19; 98():62-72. PubMed ID: 27318036
    [Abstract] [Full Text] [Related]

  • 6. Phospholamban ablation rescues sarcoplasmic reticulum Ca(2+) handling but exacerbates cardiac dysfunction in CaMKIIdelta(C) transgenic mice.
    Zhang T, Guo T, Mishra S, Dalton ND, Kranias EG, Peterson KL, Bers DM, Brown JH.
    Circ Res; 2010 Feb 05; 106(2):354-62. PubMed ID: 19959778
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  • 7. Ryanodine receptor phosphorylation by calcium/calmodulin-dependent protein kinase II promotes life-threatening ventricular arrhythmias in mice with heart failure.
    van Oort RJ, McCauley MD, Dixit SS, Pereira L, Yang Y, Respress JL, Wang Q, De Almeida AC, Skapura DG, Anderson ME, Bers DM, Wehrens XH.
    Circulation; 2010 Dec 21; 122(25):2669-79. PubMed ID: 21098440
    [Abstract] [Full Text] [Related]

  • 8. Defective calmodulin binding to the cardiac ryanodine receptor plays a key role in CPVT-associated channel dysfunction.
    Xu X, Yano M, Uchinoumi H, Hino A, Suetomi T, Ono M, Tateishi H, Oda T, Okuda S, Doi M, Kobayashi S, Yamamoto T, Ikeda Y, Ikemoto N, Matsuzaki M.
    Biochem Biophys Res Commun; 2010 Apr 09; 394(3):660-6. PubMed ID: 20226167
    [Abstract] [Full Text] [Related]

  • 9. Overexpression of CaMKIIδc in RyR2R4496C+/- knock-in mice leads to altered intracellular Ca2+ handling and increased mortality.
    Dybkova N, Sedej S, Napolitano C, Neef S, Rokita AG, Hünlich M, Brown JH, Kockskämper J, Priori SG, Pieske B, Maier LS.
    J Am Coll Cardiol; 2011 Jan 25; 57(4):469-79. PubMed ID: 21251589
    [Abstract] [Full Text] [Related]

  • 10. Ablation of phospholamban rescues reperfusion arrhythmias but exacerbates myocardium infarction in hearts with Ca2+/calmodulin kinase II constitutive phosphorylation of ryanodine receptors.
    Valverde CA, Mazzocchi G, Di Carlo MN, Ciocci Pardo A, Salas N, Ragone MI, Felice JI, Cely-Ortiz A, Consolini AE, Portiansky E, Mosca S, Kranias EG, Wehrens XHT, Mattiazzi A.
    Cardiovasc Res; 2019 Mar 01; 115(3):556-569. PubMed ID: 30169578
    [Abstract] [Full Text] [Related]

  • 11. RyR2-targeting therapy prevents left ventricular remodeling and ventricular tachycardia in post-infarction heart failure.
    Fujii S, Kobayashi S, Chang Y, Nawata J, Yoshitomi R, Tanaka S, Kohno M, Nakamura Y, Ishiguchi H, Suetomi T, Uchinoumi H, Oda T, Okuda S, Okamura T, Yamamoto T, Yano M.
    J Mol Cell Cardiol; 2023 May 01; 178():36-50. PubMed ID: 36963751
    [Abstract] [Full Text] [Related]

  • 12. CaMKII inhibition has dual effects on spontaneous Ca2+ release and Ca2+ alternans in ventricular cardiomyocytes from mice with a gain-of-function RyR2 mutation.
    Sadredini M, Haugsten Hansen M, Frisk M, Louch WE, Lehnart SE, Sjaastad I, Stokke MK.
    Am J Physiol Heart Circ Physiol; 2021 Aug 01; 321(2):H446-H460. PubMed ID: 34270372
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  • 14. Calmodulin kinase II inhibition prevents arrhythmias in RyR2(R4496C+/-) mice with catecholaminergic polymorphic ventricular tachycardia.
    Liu N, Ruan Y, Denegri M, Bachetti T, Li Y, Colombi B, Napolitano C, Coetzee WA, Priori SG.
    J Mol Cell Cardiol; 2011 Jan 01; 50(1):214-22. PubMed ID: 20937285
    [Abstract] [Full Text] [Related]

  • 15. Calcium-calmodulin-dependent protein kinase mediates the intracellular signalling pathways of cardiac apoptosis in mice with impaired glucose tolerance.
    Federico M, Portiansky EL, Sommese L, Alvarado FJ, Blanco PG, Zanuzzi CN, Dedman J, Kaetzel M, Wehrens XHT, Mattiazzi A, Palomeque J.
    J Physiol; 2017 Jun 15; 595(12):4089-4108. PubMed ID: 28105734
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  • 16. Reversible redox modifications of ryanodine receptor ameliorate ventricular arrhythmias in the ischemic-reperfused heart.
    Becerra R, Román B, Di Carlo MN, Mariangelo JI, Salas M, Sanchez G, Donoso P, Schinella GR, Vittone L, Wehrens XH, Mundiña-Weilenmann C, Said M.
    Am J Physiol Heart Circ Physiol; 2016 Sep 01; 311(3):H713-24. PubMed ID: 27422983
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  • 17. Calcium/calmodulin-dependent protein kinase II (CaMKII) inhibition ameliorates arrhythmias elicited by junctin ablation under stress conditions.
    Tzimas C, Terrovitis J, Lehnart SE, Kranias EG, Sanoudou D.
    Heart Rhythm; 2015 Jul 01; 12(7):1599-610. PubMed ID: 25814413
    [Abstract] [Full Text] [Related]

  • 18. CaMKII-dependent phosphorylation of cardiac ryanodine receptors regulates cell death in cardiac ischemia/reperfusion injury.
    Di Carlo MN, Said M, Ling H, Valverde CA, De Giusti VC, Sommese L, Palomeque J, Aiello EA, Skapura DG, Rinaldi G, Respress JL, Brown JH, Wehrens XH, Salas MA, Mattiazzi A.
    J Mol Cell Cardiol; 2014 Sep 01; 74():274-83. PubMed ID: 24949568
    [Abstract] [Full Text] [Related]

  • 19. Calcium-calmodulin kinase II mediates digitalis-induced arrhythmias.
    Gonano LA, Sepúlveda M, Rico Y, Kaetzel M, Valverde CA, Dedman J, Mattiazzi A, Vila Petroff M.
    Circ Arrhythm Electrophysiol; 2011 Dec 01; 4(6):947-57. PubMed ID: 22009705
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  • 20. Calcium/Calmodulin Protein Kinase II-Dependent Ryanodine Receptor Phosphorylation Mediates Cardiac Contractile Dysfunction Associated With Sepsis.
    Sepúlveda M, Gonano LA, Viotti M, Morell M, Blanco P, López Alarcón M, Peroba Ramos I, Bastos Carvalho A, Medei E, Vila Petroff M.
    Crit Care Med; 2017 Apr 01; 45(4):e399-e408. PubMed ID: 27648519
    [Abstract] [Full Text] [Related]

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