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Journal Abstract Search

542 related items for PubMed ID: 32083971

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  • 3. Hypertrophic cardiomyopathy mutations increase myofilament Ca2+ buffering, alter intracellular Ca2+ handling, and stimulate Ca2+-dependent signaling.
    Robinson P, Liu X, Sparrow A, Patel S, Zhang YH, Casadei B, Watkins H, Redwood C.
    J Biol Chem; 2018 Jul 06; 293(27):10487-10499. PubMed ID: 29760186
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  • 4. Dilated cardiomyopathy mutations in thin-filament regulatory proteins reduce contractility, suppress systolic Ca2+, and activate NFAT and Akt signaling.
    Robinson P, Sparrow AJ, Patel S, Malinowska M, Reilly SN, Zhang YH, Casadei B, Watkins H, Redwood C.
    Am J Physiol Heart Circ Physiol; 2020 Aug 01; 319(2):H306-H319. PubMed ID: 32618513
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  • 6. Mavacamten decreases maximal force and Ca2+ sensitivity in the N47K-myosin regulatory light chain mouse model of hypertrophic cardiomyopathy.
    Awinda PO, Watanabe M, Bishaw Y, Huckabee AM, Agonias KB, Kazmierczak K, Szczesna-Cordary D, Tanner BCW.
    Am J Physiol Heart Circ Physiol; 2021 Feb 01; 320(2):H881-H890. PubMed ID: 33337957
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  • 7. Desensitization of myofilaments to Ca2+ as a therapeutic target for hypertrophic cardiomyopathy with mutations in thin filament proteins.
    Alves ML, Dias FAL, Gaffin RD, Simon JN, Montminy EM, Biesiadecki BJ, Hinken AC, Warren CM, Utter MS, Davis RT, Sakthivel S, Robbins J, Wieczorek DF, Solaro RJ, Wolska BM.
    Circ Cardiovasc Genet; 2014 Apr 01; 7(2):132-143. PubMed ID: 24585742
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  • 10. Hypertrophic cardiomyopathy-linked mutation in troponin T causes myofibrillar disarray and pro-arrhythmic action potential changes in human iPSC cardiomyocytes.
    Wang L, Kim K, Parikh S, Cadar AG, Bersell KR, He H, Pinto JR, Kryshtal DO, Knollmann BC.
    J Mol Cell Cardiol; 2018 Jan 01; 114():320-327. PubMed ID: 29217433
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  • 12. Sexually dimorphic myofilament function and cardiac troponin I phosphospecies distribution in hypertrophic cardiomyopathy mice.
    McKee LA, Chen H, Regan JA, Behunin SM, Walker JW, Walker JS, Konhilas JP.
    Arch Biochem Biophys; 2013 Jul 01; 535(1):39-48. PubMed ID: 23352598
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  • 15. Cardiac myosin heavy chain isoform exchange alters the phenotype of cTnT-related cardiomyopathies in mouse hearts.
    Rice R, Guinto P, Dowell-Martino C, He H, Hoyer K, Krenz M, Robbins J, Ingwall JS, Tardiff JC.
    J Mol Cell Cardiol; 2010 May 01; 48(5):979-88. PubMed ID: 20004663
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  • 16. Dilated and hypertrophic cardiomyopathy mutations in troponin and alpha-tropomyosin have opposing effects on the calcium affinity of cardiac thin filaments.
    Robinson P, Griffiths PJ, Watkins H, Redwood CS.
    Circ Res; 2007 Dec 07; 101(12):1266-73. PubMed ID: 17932326
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  • 18. Diltiazem prevents stress-induced contractile deficits in cardiomyocytes, but does not reverse the cardiomyopathy phenotype in Mybpc3-knock-in mice.
    Flenner F, Geertz B, Reischmann-Düsener S, Weinberger F, Eschenhagen T, Carrier L, Friedrich FW.
    J Physiol; 2017 Jun 15; 595(12):3987-3999. PubMed ID: 28090637
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  • 19. Mutations in troponin T associated with Hypertrophic Cardiomyopathy increase Ca(2+)-sensitivity and suppress the modulation of Ca(2+)-sensitivity by troponin I phosphorylation.
    Messer AE, Bayliss CR, El-Mezgueldi M, Redwood CS, Ward DG, Leung MC, Papadaki M, Dos Remedios C, Marston SB.
    Arch Biochem Biophys; 2016 Jul 01; 601():113-20. PubMed ID: 27036851
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  • 20. Ca(2+)-regulatory function of the inhibitory peptide region of cardiac troponin I is aided by the C-terminus of cardiac troponin T: Effects of familial hypertrophic cardiomyopathy mutations cTnI R145G and cTnT R278C, alone and in combination, on filament sliding.
    Brunet NM, Chase PB, Mihajlović G, Schoffstall B.
    Arch Biochem Biophys; 2014 Jun 15; 552-553():11-20. PubMed ID: 24418317
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