These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

187 related items for PubMed ID: 32145316

  • 1. Assessment of the inhibition risk of paris saponins, bioactive compounds from Paris polyphylla, on CYP and UGT enzymes via cocktail inhibition assays.
    Luo H, Xu Y, Sun D, Cheng Y, Sun Z, Gao J, Zhang Y, Wang X.
    Regul Toxicol Pharmacol; 2020 Jun; 113():104637. PubMed ID: 32145316
    [Abstract] [Full Text] [Related]

  • 2. Design and optimization of the cocktail assay for rapid assessment of the activity of UGT enzymes in human and rat liver microsomes.
    Chen A, Zhou X, Cheng Y, Tang S, Liu M, Wang X.
    Toxicol Lett; 2018 Oct 01; 295():379-389. PubMed ID: 30036684
    [Abstract] [Full Text] [Related]

  • 3. Evaluation of the inhibition risk of shikonin on human and rat UDP-glucuronosyltransferases (UGT) through the cocktail approach.
    Cheng Y, Tang S, Chen A, Zhang Y, Liu M, Wang X.
    Toxicol Lett; 2019 Sep 15; 312():214-221. PubMed ID: 31128210
    [Abstract] [Full Text] [Related]

  • 4. Assessment of the inhibition risk of shikonin on cytochrome P450 via cocktail inhibition assay.
    Tang S, Chen A, Zhou X, Zeng L, Liu M, Wang X.
    Toxicol Lett; 2017 Nov 05; 281():74-83. PubMed ID: 28941798
    [Abstract] [Full Text] [Related]

  • 5. Metabolic interactions of rosmarinic acid with human cytochrome P450 monooxygenases and uridine diphosphate glucuronosyltransferases.
    Kim SB, Kim KS, Kim DD, Yoon IS.
    Biomed Pharmacother; 2019 Feb 05; 110():111-117. PubMed ID: 30466000
    [Abstract] [Full Text] [Related]

  • 6. Direct comparison of UDP-glucuronosyltransferase and cytochrome P450 activities in human liver microsomes, plated and suspended primary human hepatocytes from five liver donors.
    den Braver-Sewradj SP, den Braver MW, Baze A, Decorde J, Fonsi M, Bachellier P, Vermeulen NPE, Commandeur JNM, Richert L, Vos JC.
    Eur J Pharm Sci; 2017 Nov 15; 109():96-110. PubMed ID: 28778465
    [Abstract] [Full Text] [Related]

  • 7. In vitro inhibition of human liver cytochrome P450 (CYP) and UDP-glucuronosyltransferase (UGT) enzymes by rose bengal: system-dependent effects on inhibitory potential.
    Kazmi F, Haupt LJ, Horkman JR, Smith BD, Buckley DB, Wachter EA, Singer JM.
    Xenobiotica; 2014 Jul 15; 44(7):606-14. PubMed ID: 24405273
    [Abstract] [Full Text] [Related]

  • 8. Evaluation of the in vitro/in vivo drug interaction potential of BST204, a purified dry extract of ginseng, and its four bioactive ginsenosides through cytochrome P450 inhibition/induction and UDP-glucuronosyltransferase inhibition.
    Zheng YF, Bae SH, Choi EJ, Park JB, Kim SO, Jang MJ, Park GH, Shin WG, Oh E, Bae SK.
    Food Chem Toxicol; 2014 Jun 15; 68():117-27. PubMed ID: 24632066
    [Abstract] [Full Text] [Related]

  • 9. Protein-protein interactions between rat hepatic cytochromes P450 (P450s) and UDP-glucuronosyltransferases (UGTs): evidence for the functionally active UGT in P450-UGT complex.
    Ishii Y, Iwanaga M, Nishimura Y, Takeda S, Ikushiro S, Nagata K, Yamazoe Y, Mackenzie PI, Yamada H.
    Drug Metab Pharmacokinet; 2007 Oct 15; 22(5):367-76. PubMed ID: 17965520
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of human drug-metabolising cytochrome P450 and UDP-glucuronosyltransferase enzyme activities in vitro by uremic toxins.
    Barnes KJ, Rowland A, Polasek TM, Miners JO.
    Eur J Clin Pharmacol; 2014 Sep 15; 70(9):1097-106. PubMed ID: 24954688
    [Abstract] [Full Text] [Related]

  • 11. A cytochrome P450 monooxygenase responsible for the C-22 hydroxylation step in the Paris polyphylla steroidal saponin biosynthesis pathway.
    Yin Y, Gao L, Zhang X, Gao W.
    Phytochemistry; 2018 Dec 15; 156():116-123. PubMed ID: 30268044
    [Abstract] [Full Text] [Related]

  • 12. AM-2201 Inhibits Multiple Cytochrome P450 and Uridine 5'-Diphospho-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes.
    Kim JH, Kwon SS, Kong TY, Cheong JC, Kim HS, In MK, Lee HS.
    Molecules; 2017 Mar 10; 22(3):. PubMed ID: 28287454
    [Abstract] [Full Text] [Related]

  • 13. Effects of polyphyllin D, a steroidal saponin in Paris polyphylla, in growth inhibition of human breast cancer cells and in xenograft.
    Lee MS, Yuet-Wa JC, Kong SK, Yu B, Eng-Choon VO, Nai-Ching HW, Chung-Wai TM, Fung KP.
    Cancer Biol Ther; 2005 Nov 10; 4(11):1248-54. PubMed ID: 16258257
    [Abstract] [Full Text] [Related]

  • 14. Evaluation of the inhibition potential of plumbagin against cytochrome P450 using LC-MS/MS and cocktail approach.
    Chen A, Zhou X, Tang S, Liu M, Wang X.
    Sci Rep; 2016 Jun 22; 6():28482. PubMed ID: 27329697
    [Abstract] [Full Text] [Related]

  • 15. Optimized assays for human UDP-glucuronosyltransferase (UGT) activities: altered alamethicin concentration and utility to screen for UGT inhibitors.
    Walsky RL, Bauman JN, Bourcier K, Giddens G, Lapham K, Negahban A, Ryder TF, Obach RS, Hyland R, Goosen TC.
    Drug Metab Dispos; 2012 May 22; 40(5):1051-65. PubMed ID: 22357286
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of cytochrome P450 and uridine 5'-diphospho-glucuronosyltransferases by MAM-2201 in human liver microsomes.
    Kong TY, Kim JH, Kwon SS, Cheong JC, Kim HS, In MK, Lee HS.
    Arch Pharm Res; 2017 Jun 22; 40(6):727-735. PubMed ID: 28484907
    [Abstract] [Full Text] [Related]

  • 17. Inhibitory Effects of Aschantin on Cytochrome P450 and Uridine 5'-diphospho-glucuronosyltransferase Enzyme Activities in Human Liver Microsomes.
    Kwon SS, Kim JH, Jeong HU, Cho YY, Oh SR, Lee HS.
    Molecules; 2016 Apr 27; 21(5):. PubMed ID: 27128896
    [Abstract] [Full Text] [Related]

  • 18. In vitro metabolism of eupatilin by multiple cytochrome P450 and UDP-glucuronosyltransferase enzymes.
    Lee HS, Ji HY, Park EJ, Kim SY.
    Xenobiotica; 2007 Aug 27; 37(8):803-17. PubMed ID: 17701830
    [Abstract] [Full Text] [Related]

  • 19. In Vitro Metabolism of Auriculasin and Its Inhibitory Effects on Human Cytochrome P450 and UDP-Glucuronosyltransferase Enzymes.
    Shi X, Zhang G, Ge G, Guo Z, Song Y, Su D, Shan L.
    Chem Res Toxicol; 2019 Oct 21; 32(10):2125-2134. PubMed ID: 31515991
    [Abstract] [Full Text] [Related]

  • 20. Product inhibition of UDP-glucuronosyltransferase (UGT) enzymes by UDP obfuscates the inhibitory effects of UGT substrates.
    Fujiwara R, Nakajima M, Yamanaka H, Katoh M, Yokoi T.
    Drug Metab Dispos; 2008 Feb 21; 36(2):361-7. PubMed ID: 17998297
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 10.