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Journal Abstract Search

1043 related items for PubMed ID: 32212854

  • 1. Targeted Inhibition of Gut Microbial Trimethylamine N-Oxide Production Reduces Renal Tubulointerstitial Fibrosis and Functional Impairment in a Murine Model of Chronic Kidney Disease.
    Gupta N, Buffa JA, Roberts AB, Sangwan N, Skye SM, Li L, Ho KJ, Varga J, DiDonato JA, Tang WHW, Hazen SL.
    Arterioscler Thromb Vasc Biol; 2020 May; 40(5):1239-1255. PubMed ID: 32212854
    [Abstract] [Full Text] [Related]

  • 2. Nonlethal Inhibition of Gut Microbial Trimethylamine N-oxide Production Improves Cardiac Function and Remodeling in a Murine Model of Heart Failure.
    Organ CL, Li Z, Sharp TE, Polhemus DJ, Gupta N, Goodchild TT, Tang WHW, Hazen SL, Lefer DJ.
    J Am Heart Assoc; 2020 May 18; 9(10):e016223. PubMed ID: 32390485
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of microbiota-dependent TMAO production attenuates chronic kidney disease in mice.
    Zhang W, Miikeda A, Zuckerman J, Jia X, Charugundla S, Zhou Z, Kaczor-Urbanowicz KE, Magyar C, Guo F, Wang Z, Pellegrini M, Hazen SL, Nicholas SB, Lusis AJ, Shih DM.
    Sci Rep; 2021 Jan 12; 11(1):518. PubMed ID: 33436815
    [Abstract] [Full Text] [Related]

  • 4. Small molecule inhibition of gut microbial choline trimethylamine lyase activity alters host cholesterol and bile acid metabolism.
    Pathak P, Helsley RN, Brown AL, Buffa JA, Choucair I, Nemet I, Gogonea CB, Gogonea V, Wang Z, Garcia-Garcia JC, Cai L, Temel R, Sangwan N, Hazen SL, Brown JM.
    Am J Physiol Heart Circ Physiol; 2020 Jun 01; 318(6):H1474-H1486. PubMed ID: 32330092
    [Abstract] [Full Text] [Related]

  • 5. Intestinal microbiota composition modulates choline bioavailability from diet and accumulation of the proatherogenic metabolite trimethylamine-N-oxide.
    Romano KA, Vivas EI, Amador-Noguez D, Rey FE.
    mBio; 2015 Mar 17; 6(2):e02481. PubMed ID: 25784704
    [Abstract] [Full Text] [Related]

  • 6. The guanylate cyclase C agonist linaclotide ameliorates the gut-cardio-renal axis in an adenine-induced mouse model of chronic kidney disease.
    Nanto-Hara F, Kanemitsu Y, Fukuda S, Kikuchi K, Asaji K, Saigusa D, Iwasaki T, Ho HJ, Mishima E, Suzuki T, Suzuki C, Tsukimi T, Matsuhashi T, Oikawa Y, Akiyama Y, Kure S, Owada Y, Tomioka Y, Soga T, Ito S, Abe T.
    Nephrol Dial Transplant; 2020 Feb 01; 35(2):250-264. PubMed ID: 31411705
    [Abstract] [Full Text] [Related]

  • 7. Flavin monooxygenase 3, the host hepatic enzyme in the metaorganismal trimethylamine N-oxide-generating pathway, modulates platelet responsiveness and thrombosis risk.
    Zhu W, Buffa JA, Wang Z, Warrier M, Schugar R, Shih DM, Gupta N, Gregory JC, Org E, Fu X, Li L, DiDonato JA, Lusis AJ, Brown JM, Hazen SL.
    J Thromb Haemost; 2018 Sep 01; 16(9):1857-1872. PubMed ID: 29981269
    [Abstract] [Full Text] [Related]

  • 8. Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis.
    Wang Z, Roberts AB, Buffa JA, Levison BS, Zhu W, Org E, Gu X, Huang Y, Zamanian-Daryoush M, Culley MK, DiDonato AJ, Fu X, Hazen JE, Krajcik D, DiDonato JA, Lusis AJ, Hazen SL.
    Cell; 2015 Dec 17; 163(7):1585-95. PubMed ID: 26687352
    [Abstract] [Full Text] [Related]

  • 9. Gut microbiota-dependent trimethylamine N-oxide (TMAO) pathway contributes to both development of renal insufficiency and mortality risk in chronic kidney disease.
    Tang WH, Wang Z, Kennedy DJ, Wu Y, Buffa JA, Agatisa-Boyle B, Li XS, Levison BS, Hazen SL.
    Circ Res; 2015 Jan 30; 116(3):448-55. PubMed ID: 25599331
    [Abstract] [Full Text] [Related]

  • 10. Microbial Transplantation With Human Gut Commensals Containing CutC Is Sufficient to Transmit Enhanced Platelet Reactivity and Thrombosis Potential.
    Skye SM, Zhu W, Romano KA, Guo CJ, Wang Z, Jia X, Kirsop J, Haag B, Lang JM, DiDonato JA, Tang WHW, Lusis AJ, Rey FE, Fischbach MA, Hazen SL.
    Circ Res; 2018 Oct 26; 123(10):1164-1176. PubMed ID: 30359185
    [Abstract] [Full Text] [Related]

  • 11. Gut microbe-derived metabolite trimethylamine N-oxide accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis.
    Yang W, Zhang S, Zhu J, Jiang H, Jia D, Ou T, Qi Z, Zou Y, Qian J, Sun A, Ge J.
    J Mol Cell Cardiol; 2019 Sep 26; 134():119-130. PubMed ID: 31299216
    [Abstract] [Full Text] [Related]

  • 12. Berberine attenuates choline-induced atherosclerosis by inhibiting trimethylamine and trimethylamine-N-oxide production via manipulating the gut microbiome.
    Li X, Su C, Jiang Z, Yang Y, Zhang Y, Yang M, Zhang X, Du Y, Zhang J, Wang L, Jiang J, Hong B.
    NPJ Biofilms Microbiomes; 2021 Apr 16; 7(1):36. PubMed ID: 33863898
    [Abstract] [Full Text] [Related]

  • 13. Trigonelline inhibits intestinal microbial metabolism of choline and its associated cardiovascular risk.
    Anwar S, Bhandari U, Panda BP, Dubey K, Khan W, Ahmad S.
    J Pharm Biomed Anal; 2018 Sep 10; 159():100-112. PubMed ID: 29980011
    [Abstract] [Full Text] [Related]

  • 14. Gut microbes impact stroke severity via the trimethylamine N-oxide pathway.
    Zhu W, Romano KA, Li L, Buffa JA, Sangwan N, Prakash P, Tittle AN, Li XS, Fu X, Androjna C, DiDonato AJ, Brinson K, Trapp BD, Fischbach MA, Rey FE, Hajjar AM, DiDonato JA, Hazen SL.
    Cell Host Microbe; 2021 Jul 14; 29(7):1199-1208.e5. PubMed ID: 34139173
    [Abstract] [Full Text] [Related]

  • 15. Gut microbial metabolite TMAO contributes to renal dysfunction in a mouse model of diet-induced obesity.
    Sun G, Yin Z, Liu N, Bian X, Yu R, Su X, Zhang B, Wang Y.
    Biochem Biophys Res Commun; 2017 Nov 18; 493(2):964-970. PubMed ID: 28942145
    [Abstract] [Full Text] [Related]

  • 16. Metformin alleviates choline diet-induced TMAO elevation in C57BL/6J mice by influencing gut-microbiota composition and functionality.
    Su C, Li X, Yang Y, Du Y, Zhang X, Wang L, Hong B.
    Nutr Diabetes; 2021 Jul 31; 11(1):27. PubMed ID: 34389700
    [Abstract] [Full Text] [Related]

  • 17. Dietary Methionine Restriction Alleviates Choline-Induced Tri-Methylamine-N-Oxide (TMAO) Elevation by Manipulating Gut Microbiota in Mice.
    Lu M, Yang Y, Xu Y, Wang X, Li B, Le G, Xie Y.
    Nutrients; 2023 Jan 01; 15(1):. PubMed ID: 36615863
    [Abstract] [Full Text] [Related]

  • 18. Blueberry intervention mitigates detrimental microbial metabolite trimethylamine N-oxide by modulating gut microbes.
    Satheesh Babu AK, Petersen C, Iglesias-Carres L, Paz HA, Wankhade UD, Neilson AP, Anandh Babu PV.
    Biofactors; 2024 Jan 01; 50(2):392-404. PubMed ID: 37921575
    [Abstract] [Full Text] [Related]

  • 19. Transmission of atherosclerosis susceptibility with gut microbial transplantation.
    Gregory JC, Buffa JA, Org E, Wang Z, Levison BS, Zhu W, Wagner MA, Bennett BJ, Li L, DiDonato JA, Lusis AJ, Hazen SL.
    J Biol Chem; 2015 Feb 27; 290(9):5647-60. PubMed ID: 25550161
    [Abstract] [Full Text] [Related]

  • 20. The Relationship between Choline Bioavailability from Diet, Intestinal Microbiota Composition, and Its Modulation of Human Diseases.
    Arias N, Arboleya S, Allison J, Kaliszewska A, Higarza SG, Gueimonde M, Arias JL.
    Nutrients; 2020 Aug 05; 12(8):. PubMed ID: 32764281
    [Abstract] [Full Text] [Related]

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