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1514 related items for PubMed ID: 32229246

  • 1. Alpha1-antitrypsin ameliorates islet amyloid-induced glucose intolerance and β-cell dysfunction.
    Rodríguez-Comas J, Moreno-Vedia J, Obach M, Castaño C, de Pablo S, Alcarraz-Vizán G, Díaz-Catalán D, Mestre A, Horrillo R, Costa M, Novials A, Servitja JM.
    Mol Metab; 2020 Jul; 37():100984. PubMed ID: 32229246
    [Abstract] [Full Text] [Related]

  • 2. Amyloid-induced β-cell dysfunction and islet inflammation are ameliorated by 4-phenylbutyrate (PBA) treatment.
    Montane J, de Pablo S, Castaño C, Rodríguez-Comas J, Cadavez L, Obach M, Visa M, Alcarraz-Vizán G, Sanchez-Martinez M, Nonell-Canals A, Parrizas M, Servitja JM, Novials A.
    FASEB J; 2017 Dec; 31(12):5296-5306. PubMed ID: 28821639
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  • 3. Dual role of interleukin-1β in islet amyloid formation and its β-cell toxicity: Implications for type 2 diabetes and islet transplantation.
    Park YJ, Warnock GL, Ao Z, Safikhan N, Meloche M, Asadi A, Kieffer TJ, Marzban L.
    Diabetes Obes Metab; 2017 May; 19(5):682-694. PubMed ID: 28058779
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  • 9. ABCA1 deficiency and cellular cholesterol accumulation increases islet amyloidogenesis in mice.
    Wijesekara N, Kaur A, Westwell-Roper C, Nackiewicz D, Soukhatcheva G, Hayden MR, Verchere CB.
    Diabetologia; 2016 Jun; 59(6):1242-6. PubMed ID: 26970755
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  • 10. 4-Phenylbutyrate (PBA) treatment reduces hyperglycemia and islet amyloid in a mouse model of type 2 diabetes and obesity.
    de Pablo S, Rodríguez-Comas J, Díaz-Catalán D, Alcarraz-Vizán G, Castaño C, Moreno-Vedia J, Montane J, Parrizas M, Servitja JM, Novials A.
    Sci Rep; 2021 Jun 04; 11(1):11878. PubMed ID: 34088954
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  • 11. The S20G substitution in hIAPP is more amyloidogenic and cytotoxic than wild-type hIAPP in mouse islets.
    Meier DT, Entrup L, Templin AT, Hogan MF, Mellati M, Zraika S, Hull RL, Kahn SE.
    Diabetologia; 2016 Oct 04; 59(10):2166-71. PubMed ID: 27393137
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  • 12. The islet tissue plasminogen activator/plasmin system is upregulated with human islet amyloid polypeptide aggregation and protects beta cells from aggregation-induced toxicity.
    Esser N, Hogan MF, Templin AT, Akter R, Fountaine BS, Castillo JJ, El-Osta A, Manathunga L, Zhyvoloup A, Raleigh DP, Zraika S, Hull RL, Kahn SE.
    Diabetologia; 2024 Sep 04; 67(9):1897-1911. PubMed ID: 39245780
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  • 13. PAM haploinsufficiency does not accelerate the development of diet- and human IAPP-induced diabetes in mice.
    Chen YC, Mains RE, Eipper BA, Hoffman BG, Czyzyk TA, Pintar JE, Verchere CB.
    Diabetologia; 2020 Mar 04; 63(3):561-576. PubMed ID: 31984442
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  • 14. Islet amyloid polypeptide aggregation exerts cytotoxic and proinflammatory effects on the islet vasculature in mice.
    Castillo JJ, Aplin AC, Hackney DJ, Hogan MF, Esser N, Templin AT, Akter R, Kahn SE, Raleigh DP, Zraika S, Hull RL.
    Diabetologia; 2022 Oct 04; 65(10):1687-1700. PubMed ID: 35871651
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  • 15. Human islet amyloid polypeptide transgenic mice: in vivo and ex vivo models for the role of hIAPP in type 2 diabetes mellitus.
    Höppener JW, Jacobs HM, Wierup N, Sotthewes G, Sprong M, de Vos P, Berger R, Sundler F, Ahrén B.
    Exp Diabetes Res; 2008 Oct 04; 2008():697035. PubMed ID: 18497871
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  • 16. Intra- and extracellular amyloid fibrils are formed in cultured pancreatic islets of transgenic mice expressing human islet amyloid polypeptide.
    de Koning EJ, Morris ER, Hofhuis FM, Posthuma G, Höppener JW, Morris JF, Capel PJ, Clark A, Verbeek JS.
    Proc Natl Acad Sci U S A; 1994 Aug 30; 91(18):8467-71. PubMed ID: 8078905
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  • 17. beta-cell glucokinase deficiency and hyperglycemia are associated with reduced islet amyloid deposition in a mouse model of type 2 diabetes.
    Andrikopoulos S, Verchere CB, Terauchi Y, Kadowaki T, Kahn SE.
    Diabetes; 2000 Dec 30; 49(12):2056-62. PubMed ID: 11118007
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  • 18. Differences between amyloid toxicity in alpha and beta cells in human and mouse islets and the role of caspase-3.
    Law E, Lu S, Kieffer TJ, Warnock GL, Ao Z, Woo M, Marzban L.
    Diabetologia; 2010 Jul 30; 53(7):1415-27. PubMed ID: 20369225
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  • 19. cJUN N-terminal kinase (JNK) activation mediates islet amyloid-induced beta cell apoptosis in cultured human islet amyloid polypeptide transgenic mouse islets.
    Subramanian SL, Hull RL, Zraika S, Aston-Mourney K, Udayasankar J, Kahn SE.
    Diabetologia; 2012 Jan 30; 55(1):166-74. PubMed ID: 22038516
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  • 20. Combination of human tau and islet amyloid polypeptide exacerbates metabolic dysfunction in transgenic mice.
    Wijesekara N, Gonçalves RA, Ahrens R, Ha K, De Felice FG, Fraser PE.
    J Pathol; 2021 Jul 30; 254(3):244-253. PubMed ID: 33797777
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