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441 related items for PubMed ID: 32247850

  • 1. The Bcr-Abl inhibitor GNF-7 inhibits necroptosis and ameliorates acute kidney injury by targeting RIPK1 and RIPK3 kinases.
    Qin X, Hu L, Shi SN, Chen X, Zhuang C, Zhang W, Jitkaew S, Pang X, Yu J, Tan YX, Wang HY, Cai Z.
    Biochem Pharmacol; 2020 Jul; 177():113947. PubMed ID: 32247850
    [Abstract] [Full Text] [Related]

  • 2. Identification of the Raf kinase inhibitor TAK-632 and its analogues as potent inhibitors of necroptosis by targeting RIPK1 and RIPK3.
    Chen X, Zhuang C, Ren Y, Zhang H, Qin X, Hu L, Fu J, Miao Z, Chai Y, Liu ZG, Zhang H, Cai Z, Wang HY.
    Br J Pharmacol; 2019 Jun; 176(12):2095-2108. PubMed ID: 30825190
    [Abstract] [Full Text] [Related]

  • 3. The multitargeted kinase inhibitor KW-2449 ameliorates cisplatin-induced nephrotoxicity by targeting RIPK1-mediated necroptosis.
    Rui C, Shi SN, Ren W, Qin X, Zhuang C, Chen X, Chen G, Yu J, Wang HY, Cai Z.
    Biochem Pharmacol; 2021 Jun; 188():114542. PubMed ID: 33819469
    [Abstract] [Full Text] [Related]

  • 4. RIPK1 inhibitor Cpd-71 attenuates renal dysfunction in cisplatin-treated mice via attenuating necroptosis, inflammation and oxidative stress.
    Wang JN, Liu MM, Wang F, Wei B, Yang Q, Cai YT, Chen X, Liu XQ, Jiang L, Li C, Hu XW, Yu JT, Ma TT, Jin J, Wu YG, Li J, Meng XM.
    Clin Sci (Lond); 2019 Jul 31; 133(14):1609-1627. PubMed ID: 31315969
    [Abstract] [Full Text] [Related]

  • 5. Discovery of potent necroptosis inhibitors targeting RIPK1 kinase activity for the treatment of inflammatory disorder and cancer metastasis.
    Hou J, Ju J, Zhang Z, Zhao C, Li Z, Zheng J, Sheng T, Zhang H, Hu L, Yu X, Zhang W, Li Y, Wu M, Ma H, Zhang X, He S.
    Cell Death Dis; 2019 Jun 24; 10(7):493. PubMed ID: 31235688
    [Abstract] [Full Text] [Related]

  • 6. Necroptosis in 3-chloro-1, 2-propanediol (3-MCPD)-dipalmitate-induced acute kidney injury in vivo and its repression by miR-223-3p.
    Huang G, Xue J, Sun X, Wang J, Yu LL.
    Toxicology; 2018 Aug 01; 406-407():33-43. PubMed ID: 29860048
    [Abstract] [Full Text] [Related]

  • 7. N-(7-Cyano-6-(4-fluoro-3-(2-(3-(trifluoromethyl)phenyl)acetamido)phenoxy)benzo[d]thiazol-2-yl)cyclopropanecarboxamide (TAK-632) Analogues as Novel Necroptosis Inhibitors by Targeting Receptor-Interacting Protein Kinase 3 (RIPK3): Synthesis, Structure-Activity Relationships, and in Vivo Efficacy.
    Zhang H, Xu L, Qin X, Chen X, Cong H, Hu L, Chen L, Miao Z, Zhang W, Cai Z, Zhuang C.
    J Med Chem; 2019 Jul 25; 62(14):6665-6681. PubMed ID: 31095385
    [Abstract] [Full Text] [Related]

  • 8. Phenytoin inhibits necroptosis.
    von Mässenhausen A, Tonnus W, Himmerkus N, Parmentier S, Saleh D, Rodriguez D, Ousingsawat J, Ang RL, Weinberg JM, Sanz AB, Ortiz A, Zierleyn A, Becker JU, Baratte B, Desban N, Bach S, Schiessl IM, Nogusa S, Balachandran S, Anders HJ, Ting AT, Bleich M, Degterev A, Kunzelmann K, Bornstein SR, Green DR, Hugo C, Linkermann A.
    Cell Death Dis; 2018 Mar 02; 9(3):359. PubMed ID: 29500402
    [Abstract] [Full Text] [Related]

  • 9. Wogonin protects against cisplatin-induced acute kidney injury by targeting RIPK1-mediated necroptosis.
    Meng XM, Li HD, Wu WF, Ming-Kuen Tang P, Ren GL, Gao L, Li XF, Yang Y, Xu T, Ma TT, Li Z, Huang C, Zhang L, Lv XW, Li J.
    Lab Invest; 2018 Jan 02; 98(1):79-94. PubMed ID: 29200200
    [Abstract] [Full Text] [Related]

  • 10. RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury.
    Newton K, Dugger DL, Maltzman A, Greve JM, Hedehus M, Martin-McNulty B, Carano RA, Cao TC, van Bruggen N, Bernstein L, Lee WP, Wu X, DeVoss J, Zhang J, Jeet S, Peng I, McKenzie BS, Roose-Girma M, Caplazi P, Diehl L, Webster JD, Vucic D.
    Cell Death Differ; 2016 Sep 01; 23(9):1565-76. PubMed ID: 27177019
    [Abstract] [Full Text] [Related]

  • 11. 7-Hydroxycoumarin protects against cisplatin-induced acute kidney injury by inhibiting necroptosis and promoting Sox9-mediated tubular epithelial cell proliferation.
    Wu WF, Wang JN, Li Z, Wei B, Jin J, Gao L, Li HD, Li J, Chen HY, Meng XM.
    Phytomedicine; 2020 Apr 01; 69():153202. PubMed ID: 32169782
    [Abstract] [Full Text] [Related]

  • 12. Caspase-8, receptor-interacting protein kinase 1 (RIPK1), and RIPK3 regulate retinoic acid-induced cell differentiation and necroptosis.
    Someda M, Kuroki S, Miyachi H, Tachibana M, Yonehara S.
    Cell Death Differ; 2020 May 01; 27(5):1539-1553. PubMed ID: 31659279
    [Abstract] [Full Text] [Related]

  • 13. Compound-42 alleviates acute kidney injury by targeting RIPK3-mediated necroptosis.
    He XY, Wang F, Suo XG, Gu MZ, Wang JN, Xu CH, Dong YH, He Y, Zhang Y, Ji ML, Chen Y, Zhang MM, Fan YG, Wen JG, Jin J, Wang J, Li J, Zhuang CL, Liu MM, Meng XM.
    Br J Pharmacol; 2023 Oct 01; 180(20):2641-2660. PubMed ID: 37248964
    [Abstract] [Full Text] [Related]

  • 14. Zinc finger protein 91 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation.
    Zhong Y, Zhang ZH, Wang JY, Xing Y, Ri MH, Jin HL, Zuo HX, Li MY, Ma J, Jin X.
    Toxicol Lett; 2022 Mar 01; 356():75-88. PubMed ID: 34942311
    [Abstract] [Full Text] [Related]

  • 15. A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis.
    Fauster A, Rebsamen M, Huber KV, Bigenzahn JW, Stukalov A, Lardeau CH, Scorzoni S, Bruckner M, Gridling M, Parapatics K, Colinge J, Bennett KL, Kubicek S, Krautwald S, Linkermann A, Superti-Furga G.
    Cell Death Dis; 2015 May 21; 6(5):e1767. PubMed ID: 25996294
    [Abstract] [Full Text] [Related]

  • 16. High glucose-induced apoptosis and necroptosis in podocytes is regulated by UCHL1 via RIPK1/RIPK3 pathway.
    Xu Y, Gao H, Hu Y, Fang Y, Qi C, Huang J, Cai X, Wu H, Ding X, Zhang Z.
    Exp Cell Res; 2019 Sep 15; 382(2):111463. PubMed ID: 31247189
    [Abstract] [Full Text] [Related]

  • 17. RIPK3 inhibitor-AZD5423 alleviates acute kidney injury by inhibiting necroptosis and inflammation.
    Xu CH, Wang JN, Suo XG, Ji ML, He XY, Chen X, Zhu S, He Y, Xie SS, Li C, Dong ZH, Chen Y, Ni WJ, Feng XW, Liu MM, Jin J, Li Z, Meng XM.
    Int Immunopharmacol; 2022 Nov 15; 112():109262. PubMed ID: 36166972
    [Abstract] [Full Text] [Related]

  • 18. Stratifin promotes renal dysfunction in ischemic and nephrotoxic AKI mouse models via enhancing RIPK3-mediated necroptosis.
    Wang F, Wang JN, He XY, Suo XG, Li C, Ni WJ, Cai YT, He Y, Fang XY, Dong YH, Xing T, Yang YR, Zhang F, Zhong X, Zang HM, Liu MM, Li J, Meng XM, Jin J.
    Acta Pharmacol Sin; 2022 Feb 15; 43(2):330-341. PubMed ID: 33833407
    [Abstract] [Full Text] [Related]

  • 19. Differential roles of RIPK1 and RIPK3 in TNF-induced necroptosis and chemotherapeutic agent-induced cell death.
    Moriwaki K, Bertin J, Gough PJ, Orlowski GM, Chan FK.
    Cell Death Dis; 2015 Feb 12; 6(2):e1636. PubMed ID: 25675296
    [Abstract] [Full Text] [Related]

  • 20. FKBP12 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation.
    Wang Z, Feng J, Yu J, Chen G.
    J Cell Sci; 2019 May 20; 132(10):. PubMed ID: 31028177
    [Abstract] [Full Text] [Related]

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