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PUBMED FOR HANDHELDS

Journal Abstract Search


316 related items for PubMed ID: 32248002

  • 1. Targeting RAS-RAF pathway significantly improves antitumor activity of Rigosertib-derived platinum(IV) complexes and overcomes cisplatin resistance.
    Liu Z, Wang M, Wang H, Fang L, Gou S.
    Eur J Med Chem; 2020 May 15; 194():112269. PubMed ID: 32248002
    [Abstract] [Full Text] [Related]

  • 2. Platinum-Based Modification of Styrylbenzylsulfones as Multifunctional Antitumor Agents: Targeting the RAS/RAF Pathway, Enhancing Antitumor Activity, and Overcoming Multidrug Resistance.
    Liu Z, Wang M, Wang H, Fang L, Gou S.
    J Med Chem; 2020 Jan 09; 63(1):186-204. PubMed ID: 31820986
    [Abstract] [Full Text] [Related]

  • 3. Dual-targeting antitumor conjugates derived from platinum(IV) prodrugs and microtubule inhibitor CA-4 significantly exhibited potent ability to overcome cisplatin resistance.
    Huang X, Wang M, Wang C, Hu W, You Q, Yang Y, Yu C, Liao Z, Gou S, Wang H.
    Bioorg Chem; 2019 Nov 09; 92():103236. PubMed ID: 31494328
    [Abstract] [Full Text] [Related]

  • 4. Conjugation of platinum(IV) complexes with chlorambucil to overcome cisplatin resistance via a "joint action" mode toward DNA.
    Qin X, Fang L, Chen F, Gou S.
    Eur J Med Chem; 2017 Sep 08; 137():167-175. PubMed ID: 28586717
    [Abstract] [Full Text] [Related]

  • 5. Toward overcoming cisplatin resistance via sterically hindered platinum(II) complexes.
    Yu H, Gou S, Wang Z, Chen F, Fang L.
    Eur J Med Chem; 2016 May 23; 114():141-52. PubMed ID: 26974381
    [Abstract] [Full Text] [Related]

  • 6. Complexes of oxoplatin with rhein and ferulic acid ligands as platinum(iv) prodrugs with high anti-tumor activity.
    Tan MX, Wang ZF, Qin QP, Zou BQ, Liang H.
    Dalton Trans; 2020 Feb 07; 49(5):1613-1619. PubMed ID: 31942585
    [Abstract] [Full Text] [Related]

  • 7. Novel NF-κB Inhibitor-Conjugated Pt(IV) Prodrug to Enable Cancer Therapy through ROS/ER Stress and Mitochondrial Dysfunction and Overcome Multidrug Resistance.
    Wang M, Li G, Jiang G, Cai J, Liu Z, Huang R, Huang X, Wang H.
    J Med Chem; 2024 Apr 25; 67(8):6218-6237. PubMed ID: 38573870
    [Abstract] [Full Text] [Related]

  • 8. Synthesis, Cytotoxicity, and Mechanistic Investigation of Platinum(IV) Anticancer Complexes Conjugated with Poly(ADP-ribose) Polymerase Inhibitors.
    Xu Z, Li C, Zhou Q, Deng Z, Tong Z, Tse MK, Zhu G.
    Inorg Chem; 2019 Dec 02; 58(23):16279-16291. PubMed ID: 31738050
    [Abstract] [Full Text] [Related]

  • 9. Platinum(IV) prodrugs multiply targeting genomic DNA, histone deacetylases and PARP-1.
    Xu Z, Hu W, Wang Z, Gou S.
    Eur J Med Chem; 2017 Dec 01; 141():211-220. PubMed ID: 29031068
    [Abstract] [Full Text] [Related]

  • 10. Combretastatin A-4 Analogue: A Dual-Targeting and Tubulin Inhibitor Containing Antitumor Pt(IV) Moiety with a Unique Mode of Action.
    Huang X, Huang R, Gou S, Wang Z, Liao Z, Wang H.
    Bioconjug Chem; 2016 Sep 21; 27(9):2132-48. PubMed ID: 27494235
    [Abstract] [Full Text] [Related]

  • 11. A novel series of pyrazole-platinum(II) complexes as potential anti-cancer agents that induce cell cycle arrest and apoptosis in breast cancer cells.
    Czarnomysy R, Surażyński A, Muszynska A, Gornowicz A, Bielawska A, Bielawski K.
    J Enzyme Inhib Med Chem; 2018 Dec 21; 33(1):1006-1023. PubMed ID: 29862867
    [Abstract] [Full Text] [Related]

  • 12. Wentilactone B induces G2/M phase arrest and apoptosis via the Ras/Raf/MAPK signaling pathway in human hepatoma SMMC-7721 cells.
    Zhang Z, Miao L, Lv C, Sun H, Wei S, Wang B, Huang C, Jiao B.
    Cell Death Dis; 2013 Jun 06; 4(6):e657. PubMed ID: 23744357
    [Abstract] [Full Text] [Related]

  • 13. On the stability and biological behavior of cyclometallated Pt(IV) complexes with halido and aryl ligands in the axial positions.
    Escolà A, Crespo M, López C, Quirante J, Jayaraman A, Polat IH, Badía J, Baldomà L, Cascante M.
    Bioorg Med Chem; 2016 Nov 15; 24(22):5804-5815. PubMed ID: 27670096
    [Abstract] [Full Text] [Related]

  • 14. Pt(IV) prodrugs containing microtubule inhibitors displayed potent antitumor activity and ability to overcome cisplatin resistance.
    Li L, Huang X, Huang R, Gou S, Wang Z, Wang H.
    Eur J Med Chem; 2018 Aug 05; 156():666-679. PubMed ID: 30031977
    [Abstract] [Full Text] [Related]

  • 15. Novel Pt(IV) complexes containing salvigenin ligand reverse cisplatin-induced resistance by inhibiting Rap1b-mediated cancer cell stemness in esophageal squamous cell carcinoma treatments.
    Zhao J, Wu K, Yang Y, Liu D, Zhang C, Li X.
    Bioorg Chem; 2024 Jun 05; 147():107384. PubMed ID: 38643568
    [Abstract] [Full Text] [Related]

  • 16. Construction of Dual Stimuli-Responsive Platinum(IV) Hybrids with NQO1 Targeting Ability and Overcoming Cisplatin Resistance.
    Fang L, Qin X, Zhao J, Gou S.
    Inorg Chem; 2019 Feb 04; 58(3):2191-2200. PubMed ID: 30657321
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis and biological evaluation of naphthalenebenzimidizole platinum (II) complexes as potential antitumor agents.
    Liang GB, Yu YC, Wei JH, Kuang WB, Chen ZF, Zhang Y.
    Eur J Med Chem; 2020 Feb 15; 188():112033. PubMed ID: 31923857
    [Abstract] [Full Text] [Related]

  • 18. Chlorambucil-conjugated platinum(IV) prodrugs to treat triple-negative breast cancer in vitro and in vivo.
    Ma ZY, Wang DB, Song XQ, Wu YG, Chen Q, Zhao CL, Li JY, Cheng SH, Xu JY.
    Eur J Med Chem; 2018 Sep 05; 157():1292-1299. PubMed ID: 30195239
    [Abstract] [Full Text] [Related]

  • 19. Studies on antitumor mechanism of two planar platinum(II) complexes with 8-hydroxyquinoline: synthesis, characterization, cytotoxicity, cell cycle and apoptosis.
    Qin QP, Chen ZF, Qin JL, He XJ, Li YL, Liu YC, Huang KB, Liang H.
    Eur J Med Chem; 2015 Mar 06; 92():302-13. PubMed ID: 25575314
    [Abstract] [Full Text] [Related]

  • 20. Cyclometalated Ru(II)-isoquinoline complexes overcome cisplatin resistance of A549/DDP cells by downregulation of Nrf2 via Akt/GSK-3β/Fyn pathway.
    Chen L, Wang J, Cai X, Chen S, Zhang J, Li B, Chen W, Guo X, Luo H, Chen J.
    Bioorg Chem; 2022 Feb 06; 119():105516. PubMed ID: 34856444
    [Abstract] [Full Text] [Related]


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