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Journal Abstract Search

380 related items for PubMed ID: 32265225

  • 1. IRE1α Disruption in Triple-Negative Breast Cancer Cooperates with Antiangiogenic Therapy by Reversing ER Stress Adaptation and Remodeling the Tumor Microenvironment.
    Harnoss JM, Le Thomas A, Reichelt M, Guttman O, Wu TD, Marsters SA, Shemorry A, Lawrence DA, Kan D, Segal E, Merchant M, Totpal K, Crocker LM, Mesh K, Dohse M, Solon M, Modrusan Z, Rudolph J, Koeppen H, Walter P, Ashkenazi A.
    Cancer Res; 2020 Jun 01; 80(11):2368-2379. PubMed ID: 32265225
    [Abstract] [Full Text] [Related]

  • 2. Disruption of IRE1α through its kinase domain attenuates multiple myeloma.
    Harnoss JM, Le Thomas A, Shemorry A, Marsters SA, Lawrence DA, Lu M, Chen YA, Qing J, Totpal K, Kan D, Segal E, Merchant M, Reichelt M, Ackerly Wallweber H, Wang W, Clark K, Kaufman S, Beresini MH, Laing ST, Sandoval W, Lorenzo M, Wu J, Ly J, De Bruyn T, Heidersbach A, Haley B, Gogineni A, Weimer RM, Lee D, Braun MG, Rudolph J, VanWyngarden MJ, Sherbenou DW, Gomez-Bougie P, Amiot M, Acosta-Alvear D, Walter P, Ashkenazi A.
    Proc Natl Acad Sci U S A; 2019 Aug 13; 116(33):16420-16429. PubMed ID: 31371506
    [Abstract] [Full Text] [Related]

  • 3. Targeting the IRE1α/XBP1s pathway suppresses CARM1-expressing ovarian cancer.
    Lin J, Liu H, Fukumoto T, Zundell J, Yan Q, Tang CA, Wu S, Zhou W, Guo D, Karakashev S, Hu CA, Sarma K, Kossenkov AV, Zhang R.
    Nat Commun; 2021 Sep 07; 12(1):5321. PubMed ID: 34493732
    [Abstract] [Full Text] [Related]

  • 4. IRE1α inhibitor enhances paclitaxel sensitivity of triple-negative breast cancer cells.
    Wu M, Zhang L, Pi L, Liu L, Wang S, Wu Y, Pan H, Liu M, Yi Z.
    Cell Oncol (Dordr); 2024 Oct 07; 47(5):1797-1809. PubMed ID: 38888849
    [Abstract] [Full Text] [Related]

  • 5. Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in ARID1A-Mutant Ovarian Cancers.
    Zundell JA, Fukumoto T, Lin J, Fatkhudinov N, Nacarelli T, Kossenkov AV, Liu Q, Cassel J, Hu CA, Wu S, Zhang R.
    Cancer Res; 2021 Oct 15; 81(20):5325-5335. PubMed ID: 34548333
    [Abstract] [Full Text] [Related]

  • 6. Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase.
    Merlot AM, Shafie NH, Yu Y, Richardson V, Jansson PJ, Sahni S, Lane DJR, Kovacevic Z, Kalinowski DS, Richardson DR.
    Biochem Pharmacol; 2016 Jun 01; 109():27-47. PubMed ID: 27059255
    [Abstract] [Full Text] [Related]

  • 7. ER stress and distinct outputs of the IRE1α RNase control proliferation and senescence in response to oncogenic Ras.
    Blazanin N, Son J, Craig-Lucas AB, John CL, Breech KJ, Podolsky MA, Glick AB.
    Proc Natl Acad Sci U S A; 2017 Sep 12; 114(37):9900-9905. PubMed ID: 28847931
    [Abstract] [Full Text] [Related]

  • 8. Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma.
    Mimura N, Fulciniti M, Gorgun G, Tai YT, Cirstea D, Santo L, Hu Y, Fabre C, Minami J, Ohguchi H, Kiziltepe T, Ikeda H, Kawano Y, French M, Blumenthal M, Tam V, Kertesz NL, Malyankar UM, Hokenson M, Pham T, Zeng Q, Patterson JB, Richardson PG, Munshi NC, Anderson KC.
    Blood; 2012 Jun 14; 119(24):5772-81. PubMed ID: 22538852
    [Abstract] [Full Text] [Related]

  • 9. IRE1α dissociates with BiP and inhibits ER stress-mediated apoptosis in cartilage development.
    Han X, Zhou J, Zhang P, Song F, Jiang R, Li M, Xia F, Guo FJ.
    Cell Signal; 2013 Nov 14; 25(11):2136-46. PubMed ID: 23816533
    [Abstract] [Full Text] [Related]

  • 10. Triazoloacridone C-1305 impairs XBP1 splicing by acting as a potential IRE1α endoribonuclease inhibitor.
    Bartoszewska S, Króliczewski J, Crossman DK, Pogorzelska A, Bagiński M, Collawn JF, Bartoszewski R.
    Cell Mol Biol Lett; 2021 Mar 17; 26(1):11. PubMed ID: 33730996
    [Abstract] [Full Text] [Related]

  • 11. Parallel Signaling through IRE1α and PERK Regulates Pancreatic Neuroendocrine Tumor Growth and Survival.
    Moore PC, Qi JY, Thamsen M, Ghosh R, Peng J, Gliedt MJ, Meza-Acevedo R, Warren RE, Hiniker A, Kim GE, Maly DJ, Backes BJ, Papa FR, Oakes SA.
    Cancer Res; 2019 Dec 15; 79(24):6190-6203. PubMed ID: 31672843
    [Abstract] [Full Text] [Related]

  • 12. ATF6 upregulates XBP1S and inhibits ER stress-mediated apoptosis in osteoarthritis cartilage.
    Guo FJ, Xiong Z, Lu X, Ye M, Han X, Jiang R.
    Cell Signal; 2014 Feb 15; 26(2):332-42. PubMed ID: 24269637
    [Abstract] [Full Text] [Related]

  • 13. SARS-CoV-2 Diverges from Other Betacoronaviruses in Only Partially Activating the IRE1α/XBP1 Endoplasmic Reticulum Stress Pathway in Human Lung-Derived Cells.
    Nguyen LC, Renner DM, Silva D, Yang D, Parenti NA, Medina KM, Nicolaescu V, Gula H, Drayman N, Valdespino A, Mohamed A, Dann C, Wannemo K, Robinson-Mailman L, Gonzalez A, Stock L, Cao M, Qiao Z, Moellering RE, Tay S, Randall G, Beers MF, Rosner MR, Oakes SA, Weiss SR.
    mBio; 2022 Oct 26; 13(5):e0241522. PubMed ID: 36125275
    [Abstract] [Full Text] [Related]

  • 14. IRE1α Activation in Bone Marrow-Derived Dendritic Cells Modulates Innate Recognition of Melanoma Cells and Favors CD8+ T Cell Priming.
    Medel B, Costoya C, Fernandez D, Pereda C, Lladser A, Sauma D, Pacheco R, Iwawaki T, Salazar-Onfray F, Osorio F.
    Front Immunol; 2018 Oct 26; 9():3050. PubMed ID: 30687308
    [Abstract] [Full Text] [Related]

  • 15. Screening and identification of inhibitors of endoplasmic reticulum stress-induced activation of the IRE1α-XBP1 branch.
    Tashiro E.
    J Antibiot (Tokyo); 2019 Dec 26; 72(12):899-905. PubMed ID: 31399644
    [Abstract] [Full Text] [Related]

  • 16. Interplay between the oxidoreductase PDIA6 and microRNA-322 controls the response to disrupted endoplasmic reticulum calcium homeostasis.
    Groenendyk J, Peng Z, Dudek E, Fan X, Mizianty MJ, Dufey E, Urra H, Sepulveda D, Rojas-Rivera D, Lim Y, Kim DH, Baretta K, Srikanth S, Gwack Y, Ahnn J, Kaufman RJ, Lee SK, Hetz C, Kurgan L, Michalak M.
    Sci Signal; 2014 Jun 10; 7(329):ra54. PubMed ID: 24917591
    [Abstract] [Full Text] [Related]

  • 17. Loss of p53 enhances the function of the endoplasmic reticulum through activation of the IRE1α/XBP1 pathway.
    Namba T, Chu K, Kodama R, Byun S, Yoon KW, Hiraki M, Mandinova A, Lee SW.
    Oncotarget; 2015 Aug 21; 6(24):19990-20001. PubMed ID: 26254280
    [Abstract] [Full Text] [Related]

  • 18. Sustained IRE1 and ATF6 signaling is important for survival of melanoma cells undergoing ER stress.
    Tay KH, Luan Q, Croft A, Jiang CC, Jin L, Zhang XD, Tseng HY.
    Cell Signal; 2014 Feb 21; 26(2):287-94. PubMed ID: 24240056
    [Abstract] [Full Text] [Related]

  • 19. IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling.
    Sheng X, Nenseth HZ, Qu S, Kuzu OF, Frahnow T, Simon L, Greene S, Zeng Q, Fazli L, Rennie PS, Mills IG, Danielsen H, Theis F, Patterson JB, Jin Y, Saatcioglu F.
    Nat Commun; 2019 Jan 24; 10(1):323. PubMed ID: 30679434
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of IRE1α-driven pro-survival pathways is a promising therapeutic application in acute myeloid leukemia.
    Sun H, Lin DC, Guo X, Kharabi Masouleh B, Gery S, Cao Q, Alkan S, Ikezoe T, Akiba C, Paquette R, Chien W, Müller-Tidow C, Jing Y, Agelopoulos K, Müschen M, Koeffler HP.
    Oncotarget; 2016 Apr 05; 7(14):18736-49. PubMed ID: 26934650
    [Abstract] [Full Text] [Related]

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