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186 related items for PubMed ID: 32298758
21. Precipitation in the small intestine may play a more important role in the in vivo performance of poorly soluble weak bases in the fasted state: case example nelfinavir. Shono Y, Jantratid E, Dressman JB. Eur J Pharm Biopharm; 2011 Oct; 79(2):349-56. PubMed ID: 21527341 [Abstract] [Full Text] [Related]
22. Impact of Eudragit EPO and hydroxypropyl methylcellulose on drug release rate, supersaturation, precipitation outcome and redissolution rate of indomethacin amorphous solid dispersions. Xie T, Gao W, Taylor LS. Int J Pharm; 2017 Oct 05; 531(1):313-323. PubMed ID: 28844901 [Abstract] [Full Text] [Related]
23. Evaluating the predictability of the in vitro transfer model and in vivo rat studies as a surrogate to investigate the supersaturation and precipitation behaviour of different Albendazole formulations for humans. Ruff A, Holm R, Kostewicz ES. Eur J Pharm Sci; 2017 Jul 15; 105():108-118. PubMed ID: 28473227 [Abstract] [Full Text] [Related]
24. Enhancement of the apparent solubility and bioavailability of Tadalafil nanoparticles via antisolvent precipitation. Rao Q, Qiu Z, Huang D, Lu T, Zhang ZJ, Luo D, Pan P, Zhang L, Liu Y, Guan S, Li Q. Eur J Pharm Sci; 2019 Feb 01; 128():222-231. PubMed ID: 30553058 [Abstract] [Full Text] [Related]
25. Evaluation of the Impact of Excipients and an Albendazole Salt on Albendazole Concentrations in Upper Small Intestine Using an In Vitro Biorelevant Gastrointestinal Transfer (BioGIT) System. Kourentas A, Vertzoni M, Khadra I, Symillides M, Clark H, Halbert G, Butler J, Reppas C. J Pharm Sci; 2016 Sep 01; 105(9):2896-2903. PubMed ID: 27372549 [Abstract] [Full Text] [Related]
26. Dissolution behavior of co-amorphous amino acid-indomethacin mixtures: The ability of amino acids to stabilize the supersaturated state of indomethacin. Ojarinta R, Heikkinen AT, Sievänen E, Laitinen R. Eur J Pharm Biopharm; 2017 Mar 01; 112():85-95. PubMed ID: 27888143 [Abstract] [Full Text] [Related]
27. Model-Based Analysis of Biopharmaceutic Experiments To Improve Mechanistic Oral Absorption Modeling: An Integrated in Vitro in Vivo Extrapolation Perspective Using Ketoconazole as a Model Drug. Pathak SM, Ruff A, Kostewicz ES, Patel N, Turner DB, Jamei M. Mol Pharm; 2017 Dec 04; 14(12):4305-4320. PubMed ID: 28771009 [Abstract] [Full Text] [Related]
28. Intestinal bile secretion promotes drug absorption from lipid colloidal phases via induction of supersaturation. Yeap YY, Trevaskis NL, Quach T, Tso P, Charman WN, Porter CJ. Mol Pharm; 2013 May 06; 10(5):1874-89. PubMed ID: 23480483 [Abstract] [Full Text] [Related]
29. Characterization and optimization of AMG 517 supersaturatable self-emulsifying drug delivery system (S-SEDDS) for improved oral absorption. Gao P, Akrami A, Alvarez F, Hu J, Li L, Ma C, Surapaneni S. J Pharm Sci; 2009 Feb 06; 98(2):516-28. PubMed ID: 18543293 [Abstract] [Full Text] [Related]
30. Increasing the Robustness of Biopharmaceutical Precipitation Assays - Part II: Recommendations on the use of FaSSIF. Krollik K, Lehmann A, Wagner C, Kaidas J, Bülhoff J, Kubas H, Weitschies W. J Pharm Sci; 2022 Jan 06; 111(1):155-163. PubMed ID: 34461113 [Abstract] [Full Text] [Related]
31. A win-win solution in oral delivery of lipophilic drugs: supersaturation via amorphous solid dispersions increases apparent solubility without sacrifice of intestinal membrane permeability. Miller JM, Beig A, Carr RA, Spence JK, Dahan A. Mol Pharm; 2012 Jul 02; 9(7):2009-16. PubMed ID: 22632106 [Abstract] [Full Text] [Related]
32. Physicochemical properties of tadalafil solid dispersions - Impact of polymer on the apparent solubility and dissolution rate of tadalafil. Wlodarski K, Sawicki W, Haber K, Knapik J, Wojnarowska Z, Paluch M, Lepek P, Hawelek L, Tajber L. Eur J Pharm Biopharm; 2015 Aug 02; 94():106-15. PubMed ID: 25998701 [Abstract] [Full Text] [Related]
33. Supersaturation and Precipitation of Posaconazole Upon Entry in the Upper Small Intestine in Humans. Hens B, Brouwers J, Corsetti M, Augustijns P. J Pharm Sci; 2016 Sep 02; 105(9):2677-2684. PubMed ID: 26505884 [Abstract] [Full Text] [Related]
34. A Combined In-Vitro and GastroPlus® Modeling to Study the Effect of Intestinal Precipitation on Cinnarizine Plasma Profile in a Fasted State. Kesharwani SS, Ibrahim F. AAPS PharmSciTech; 2023 May 12; 24(5):121. PubMed ID: 37173520 [Abstract] [Full Text] [Related]
35. Supersaturation-nucleation behavior of poorly soluble drugs and its impact on the oral absorption of drugs in thermodynamically high-energy forms. Ozaki S, Minamisono T, Yamashita T, Kato T, Kushida I. J Pharm Sci; 2012 Jan 12; 101(1):214-22. PubMed ID: 21918988 [Abstract] [Full Text] [Related]
36. Supersaturation and Precipitation Applicated in Drug Delivery Systems: Development Strategies and Evaluation Approaches. Gan Y, Baak JPA, Chen T, Ye H, Liao W, Lv H, Wen C, Zheng S. Molecules; 2023 Feb 27; 28(5):. PubMed ID: 36903470 [Abstract] [Full Text] [Related]
37. Quantitative Investigation of Intestinal Drug Absorption Enhancement by Drug-Rich Nanodroplets Generated via Liquid-Liquid Phase Separation. Yoshikawa E, Ueda K, Hakata R, Higashi K, Moribe K. Mol Pharm; 2024 Apr 01; 21(4):1745-1755. PubMed ID: 38501717 [Abstract] [Full Text] [Related]
38. Gastrointestinal dissolution, supersaturation and precipitation of the weak base indinavir in healthy volunteers. Rubbens J, Brouwers J, Tack J, Augustijns P. Eur J Pharm Biopharm; 2016 Dec 01; 109():122-129. PubMed ID: 27693678 [Abstract] [Full Text] [Related]
39. Effectiveness of supersaturation promoting excipients on albendazole concentrations in upper gastrointestinal lumen of fasted healthy adults. Kourentas A, Vertzoni M, Symillides M, Goumas K, Gibbon R, Butler J, Reppas C. Eur J Pharm Sci; 2016 Aug 25; 91():11-9. PubMed ID: 27185297 [Abstract] [Full Text] [Related]
40. An Insight into Different Stabilization Mechanisms of Phenytoin Derivatives Supersaturation by HPMC and PVP. Otsuka N, Ueda K, Ohyagi N, Shimizu K, Katakawa K, Kumamoto T, Higashi K, Yamamoto K, Moribe K. J Pharm Sci; 2015 Aug 25; 104(8):2574-82. PubMed ID: 26059285 [Abstract] [Full Text] [Related] Page: [Previous] [Next] [New Search]