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246 related items for PubMed ID: 32313953
1. High resolution crystal structure of a KRAS promoter G-quadruplex reveals a dimer with extensive poly-A π-stacking interactions for small-molecule recognition. Ou A, Schmidberger JW, Wilson KA, Evans CW, Hargreaves JA, Grigg M, O'Mara ML, Iyer KS, Bond CS, Smith NM. Nucleic Acids Res; 2020 Jun 04; 48(10):5766-5776. PubMed ID: 32313953 [Abstract] [Full Text] [Related]
2. High-resolution three-dimensional NMR structure of the KRAS proto-oncogene promoter reveals key features of a G-quadruplex involved in transcriptional regulation. Kerkour A, Marquevielle J, Ivashchenko S, Yatsunyk LA, Mergny JL, Salgado GF. J Biol Chem; 2017 May 12; 292(19):8082-8091. PubMed ID: 28330874 [Abstract] [Full Text] [Related]
4. Identification and characterization of a new G-quadruplex forming region within the kRAS promoter as a transcriptional regulator. Morgan RK, Batra H, Gaerig VC, Hockings J, Brooks TA. Biochim Biophys Acta; 2016 Feb 12; 1859(2):235-45. PubMed ID: 26597160 [Abstract] [Full Text] [Related]
8. The KRAS promoter responds to Myc-associated zinc finger and poly(ADP-ribose) polymerase 1 proteins, which recognize a critical quadruplex-forming GA-element. Cogoi S, Paramasivam M, Membrino A, Yokoyama KK, Xodo LE. J Biol Chem; 2010 Jul 16; 285(29):22003-16. PubMed ID: 20457603 [Abstract] [Full Text] [Related]
9. KRAS promoter oligonucleotide with decoy activity dimerizes into a unique topology consisting of two G-quadruplex units. Podbevšek P, Plavec J. Nucleic Acids Res; 2016 Jan 29; 44(2):917-25. PubMed ID: 26656490 [Abstract] [Full Text] [Related]
14. KRAS Promoter G-Quadruplexes from Sequences of Different Length: A Physicochemical Study. D'Aria F, Pagano B, Petraccone L, Giancola C. Int J Mol Sci; 2021 Jan 05; 22(1):. PubMed ID: 33466280 [Abstract] [Full Text] [Related]
15. Characterization of clinically used oral antiseptics as quadruplex-binding ligands. Calabrese DR, Zlotkowski K, Alden S, Hewitt WM, Connelly CM, Wilson RM, Gaikwad S, Chen L, Guha R, Thomas CJ, Mock BA, Schneekloth JS. Nucleic Acids Res; 2018 Apr 06; 46(6):2722-2732. PubMed ID: 29481610 [Abstract] [Full Text] [Related]
16. The human AP-endonuclease 1 (APE1) is a DNA G-quadruplex structure binding protein and regulates KRAS expression in pancreatic ductal adenocarcinoma cells. Pramanik S, Chen Y, Song H, Khutsishvili I, Marky LA, Ray S, Natarajan A, Singh PK, Bhakat KK. Nucleic Acids Res; 2022 Apr 08; 50(6):3394-3412. PubMed ID: 35286386 [Abstract] [Full Text] [Related]
17. Critical role of hnRNP A1 in activating KRAS transcription in pancreatic cancer cells: A molecular mechanism involving G4 DNA. Cogoi S, Rapozzi V, Cauci S, Xodo LE. Biochim Biophys Acta Gen Subj; 2017 May 08; 1861(5 Pt B):1389-1398. PubMed ID: 27888145 [Abstract] [Full Text] [Related]
18. Porphyrins to restrict progression of pancreatic cancer by stabilizing KRAS G-quadruplex: In silico, in vitro and in vivo validation of anticancer strategy. Pattanayak R, Barua A, Das A, Chatterjee T, Pathak A, Choudhury P, Sen S, Saha P, Bhattacharyya M. Eur J Pharm Sci; 2018 Dec 01; 125():39-53. PubMed ID: 30223034 [Abstract] [Full Text] [Related]
19. Indoloquinoline-Mediated Targeted Downregulation of KRAS through Selective Stabilization of the Mid-Promoter G-Quadruplex Structure. Psaras AM, Carty RK, Miller JT, Tumey LN, Brooks TA. Genes (Basel); 2022 Aug 13; 13(8):. PubMed ID: 36011352 [Abstract] [Full Text] [Related]
20. Binding of quinazolinones to c-KIT G-quadruplex; an interplay between hydrogen bonding and π-π stacking. Moghaddam KG, de Vries AH, Marrink SJ, Faraji S. Biophys Chem; 2019 Oct 13; 253():106220. PubMed ID: 31302375 [Abstract] [Full Text] [Related] Page: [Next] [New Search]