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Journal Abstract Search

270 related items for PubMed ID: 32320483

  • 1. Clinically Relevant Cytochrome P450 3A4 Induction Mechanisms and Drug Screening in Three-Dimensional Spheroid Cultures of Primary Human Hepatocytes.
    Hendriks DFG, Vorrink SU, Smutny T, Sim SC, Nordling Å, Ullah S, Kumondai M, Jones BC, Johansson I, Andersson TB, Lauschke VM, Ingelman-Sundberg M.
    Clin Pharmacol Ther; 2020 Oct; 108(4):844-855. PubMed ID: 32320483
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  • 5. CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes.
    Luo G, Cunningham M, Kim S, Burn T, Lin J, Sinz M, Hamilton G, Rizzo C, Jolley S, Gilbert D, Downey A, Mudra D, Graham R, Carroll K, Xie J, Madan A, Parkinson A, Christ D, Selling B, LeCluyse E, Gan LS.
    Drug Metab Dispos; 2002 Jul; 30(7):795-804. PubMed ID: 12065438
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  • 7. Megestrol acetate is a specific inducer of CYP3A4 mediated by human pregnane X receptor.
    Chen Y, Tang Y, Nie JZ, Zhang Y, Nie D.
    Cancer Chemother Pharmacol; 2021 Dec; 88(6):985-996. PubMed ID: 34524495
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  • 8. Modulation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation by ursolic acid (UA) attenuates rifampin-isoniazid cytotoxicity.
    Chang HY, Chen CJ, Ma WC, Cheng WK, Lin YN, Lee YR, Chen JJ, Lim YP.
    Phytomedicine; 2017 Dec 01; 36():37-49. PubMed ID: 29157826
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  • 10. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
    Cerveny L, Svecova L, Anzenbacherova E, Vrzal R, Staud F, Dvorak Z, Ulrichova J, Anzenbacher P, Pavek P.
    Drug Metab Dispos; 2007 Jul 01; 35(7):1032-41. PubMed ID: 17392393
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  • 11. Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor.
    Casabar RC, Das PC, Dekrey GK, Gardiner CS, Cao Y, Rose RL, Wallace AD.
    Toxicol Appl Pharmacol; 2010 Jun 15; 245(3):335-43. PubMed ID: 20361990
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  • 12. A comparison of hepato-cellular in vitro platforms to study CYP3A4 induction.
    Bulutoglu B, Rey-Bedón C, Mert S, Tian L, Jang YY, Yarmush ML, Usta OB.
    PLoS One; 2020 Jun 15; 15(2):e0229106. PubMed ID: 32106230
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  • 13. Constitutive androstane receptor weakens the induction of panaxytriol on CYP3A4 by repressing the activation of pregnane X receptor.
    Hu Q, Yao N, Wu J, Liu M, Liu F, Zhang H, Xiong Y, Xia C.
    Biochem Pharmacol; 2019 Jan 15; 159():32-39. PubMed ID: 30414935
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  • 14. Induction of human cytochrome P450 3A4 by the irreversible myeloperoxidase inactivator PF-06282999 is mediated by the pregnane X receptor.
    Moscovitz JE, Lin Z, Johnson N, Tu M, Goosen TC, Weng Y, Kalgutkar AS.
    Xenobiotica; 2018 Jul 15; 48(7):647-655. PubMed ID: 28685622
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  • 15. Mechanistic Insights of Phenobarbital-Mediated Activation of Human but Not Mouse Pregnane X Receptor.
    Li L, Welch MA, Li Z, Mackowiak B, Heyward S, Swaan PW, Wang H.
    Mol Pharmacol; 2019 Sep 15; 96(3):345-354. PubMed ID: 31436536
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  • 17. Differences in the induction of cytochrome P450 3A4 by taxane anticancer drugs, docetaxel and paclitaxel, assessed employing primary human hepatocytes.
    Nallani SC, Goodwin B, Buckley AR, Buckley DJ, Desai PB.
    Cancer Chemother Pharmacol; 2004 Sep 15; 54(3):219-29. PubMed ID: 15175893
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  • 20. Quantitative Cytochrome P450 3A4 Induction Risk Assessment Using Human Hepatocytes Complemented with Pregnane X Receptor-Activating Profiles.
    Ekiciler A, Chen WLK, Bo Y, Pugliano A, Donzelli M, Parrott N, Umehara K.
    Drug Metab Dispos; 2023 Mar 15; 51(3):276-284. PubMed ID: 36460477
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