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248 related items for PubMed ID: 32326257

  • 1. Targeting Trypanothione Reductase, a Key Enzyme in the Redox Trypanosomatid Metabolism, to Develop New Drugs against Leishmaniasis and Trypanosomiases.
    Battista T, Colotti G, Ilari A, Fiorillo A.
    Molecules; 2020 Apr 21; 25(8):. PubMed ID: 32326257
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  • 3. Targeting Trypanothione Metabolism in Trypanosomatids.
    González-Montero MC, Andrés-Rodríguez J, García-Fernández N, Pérez-Pertejo Y, Reguera RM, Balaña-Fouce R, García-Estrada C.
    Molecules; 2024 May 09; 29(10):. PubMed ID: 38792079
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  • 4. Thiol redox biology of trypanosomatids and potential targets for chemotherapy.
    Leroux AE, Krauth-Siegel RL.
    Mol Biochem Parasitol; 2016 May 09; 206(1-2):67-74. PubMed ID: 26592324
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  • 9. Phenothiazine inhibitors of trypanothione reductase as potential antitrypanosomal and antileishmanial drugs.
    Chan C, Yin H, Garforth J, McKie JH, Jaouhari R, Speers P, Douglas KT, Rock PJ, Yardley V, Croft SL, Fairlamb AH.
    J Med Chem; 1998 Jan 15; 41(2):148-56. PubMed ID: 9457238
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  • 11. Biological Evaluation and X-ray Co-crystal Structures of Cyclohexylpyrrolidine Ligands for Trypanothione Reductase, an Enzyme from the Redox Metabolism of Trypanosoma.
    De Gasparo R, Brodbeck-Persch E, Bryson S, Hentzen NB, Kaiser M, Pai EF, Krauth-Siegel RL, Diederich F.
    ChemMedChem; 2018 May 08; 13(9):957-967. PubMed ID: 29624890
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  • 14. Parasite-specific trypanothione reductase as a drug target molecule.
    Krauth-Siegel RL, Inhoff O.
    Parasitol Res; 2003 Jun 08; 90 Suppl 2():S77-85. PubMed ID: 12709793
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  • 16. Binding to large enzyme pockets: small-molecule inhibitors of trypanothione reductase.
    Persch E, Bryson S, Todoroff NK, Eberle C, Thelemann J, Dirdjaja N, Kaiser M, Weber M, Derbani H, Brun R, Schneider G, Pai EF, Krauth-Siegel RL, Diederich F.
    ChemMedChem; 2014 Aug 08; 9(8):1880-91. PubMed ID: 24788386
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  • 17. Spiro-containing derivatives show antiparasitic activity against Trypanosoma brucei through inhibition of the trypanothione reductase enzyme.
    Turcano L, Battista T, De Haro ET, Missineo A, Alli C, Paonessa G, Colotti G, Harper S, Fiorillo A, Ilari A, Bresciani A.
    PLoS Negl Trop Dis; 2020 May 08; 14(5):e0008339. PubMed ID: 32437349
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  • 18. Developing imidazole analogues as potential inhibitor for Leishmania donovani trypanothione reductase: virtual screening, molecular docking, dynamics and ADMET approach.
    Pandey RK, Sharma D, Bhatt TK, Sundar S, Prajapati VK.
    J Biomol Struct Dyn; 2015 May 08; 33(12):2541-53. PubMed ID: 26305585
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  • 20. Kinetoplast as a potential chemotherapeutic target of trypanosomatids.
    Motta MC.
    Curr Pharm Des; 2008 May 08; 14(9):847-54. PubMed ID: 18473834
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