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Journal Abstract Search

201 related items for PubMed ID: 32339853

  • 21. Identification of novel non-toxic and anti-angiogenic α-fluorinated chalcones as potent colchicine binding site inhibitors.
    Sun M, Yuan M, Kang Y, Qin J, Zhang Y, Duan Y, Wang L, Yao Y.
    J Enzyme Inhib Med Chem; 2022 Dec; 37(1):339-354. PubMed ID: 34979843
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  • 22. Synthesis and biological evaluation of substituted N-(2-(1H-benzo[d]imidazol-2-yl)phenyl)cinnamides as tubulin polymerization inhibitors.
    Donthiboina K, Anchi P, Gurram S, Sai Mani G, Lakshmi Uppu J, Godugu C, Shankaraiah N, Kamal A.
    Bioorg Chem; 2020 Oct; 103():104191. PubMed ID: 32891862
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  • 23. (E)-N-Aryl-2-oxo-2-(3,4,5-trimethoxyphenyl)acetohydrazonoyl cyanides as tubulin polymerization inhibitors: Structure-based bioisosterism design, synthesis, biological evaluation, molecular docking and in silico ADME prediction.
    Wang G, Peng Z, Peng S, Qiu J, Li Y, Lan Y.
    Bioorg Med Chem Lett; 2018 Nov 01; 28(20):3350-3355. PubMed ID: 30197030
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  • 24. Synthesis and biological evaluation of quinoxaline derivatives as tubulin polymerization inhibitors that elevate intracellular ROS and triggers apoptosis via mitochondrial pathway.
    Qi J, Huang J, Zhou X, Luo W, Xie J, Niu L, Yan Z, Luo Y, Men Y, Chen Y, Zhang Y, Wang J.
    Chem Biol Drug Des; 2019 Apr 01; 93(4):617-627. PubMed ID: 30635972
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  • 25. Discovery of Novel Quinoline-Chalcone Derivatives as Potent Antitumor Agents with Microtubule Polymerization Inhibitory Activity.
    Li W, Xu F, Shuai W, Sun H, Yao H, Ma C, Xu S, Yao H, Zhu Z, Yang DH, Chen ZS, Xu J.
    J Med Chem; 2019 Jan 24; 62(2):993-1013. PubMed ID: 30525584
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  • 26. Synthesis of different heterocycles-linked chalcone conjugates as cytotoxic agents and tubulin polymerization inhibitors.
    Shankaraiah N, Nekkanti S, Brahma UR, Praveen Kumar N, Deshpande N, Prasanna D, Senwar KR, Jaya Lakshmi U.
    Bioorg Med Chem; 2017 Sep 01; 25(17):4805-4816. PubMed ID: 28774575
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  • 27. Synthesis of phenstatin/isocombretastatin-chalcone conjugates as potent tubulin polymerization inhibitors and mitochondrial apoptotic inducers.
    Kamal A, Kumar GB, Vishnuvardhan MV, Shaik AB, Reddy VS, Mahesh R, Sayeeda IB, Kapure JS.
    Org Biomol Chem; 2015 Apr 07; 13(13):3963-81. PubMed ID: 25721862
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  • 28. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
    Romagnoli R, Kimatrai Salvador M, Schiaffino Ortega S, Baraldi PG, Oliva P, Baraldi S, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Balzarini J, Liekens S, Mattiuzzo E, Basso G, Viola G.
    Eur J Med Chem; 2018 Jan 01; 143():683-698. PubMed ID: 29220790
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  • 29. Synthesis and structure-activity relationships of 5-phenyloxazole-2-carboxylic acid derivatives as novel inhibitors of tubulin polymerization.
    Zhang R, Mo H, Ma YY, Zhao DG, Zhang K, Zhang T, Chen X, Zheng X.
    Bioorg Med Chem Lett; 2021 May 15; 40():127968. PubMed ID: 33753264
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  • 30. Structure-Activity Relationship Study of Novel 6-Aryl-2-benzoyl-pyridines as Tubulin Polymerization Inhibitors with Potent Antiproliferative Properties.
    Chen H, Deng S, Wang Y, Albadari N, Kumar G, Ma D, Li W, White SW, Miller DD, Li W.
    J Med Chem; 2020 Jan 23; 63(2):827-846. PubMed ID: 31860298
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  • 31. Design, synthesis, and bioevaluation of pyrazolo[1,5-a]pyrimidine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site with potent anticancer activities.
    Li G, Wang Y, Li L, Ren Y, Deng X, Liu J, Wang W, Luo M, Liu S, Chen J.
    Eur J Med Chem; 2020 Sep 15; 202():112519. PubMed ID: 32650183
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  • 32. Development of triazolothiadiazine derivatives as highly potent tubulin polymerization inhibitors: Structure-activity relationship, in vitro and in vivo study.
    Ma W, Chen P, Huo X, Ma Y, Li Y, Diao P, Yang F, Zheng S, Hu M, You W, Zhao P.
    Eur J Med Chem; 2020 Dec 15; 208():112847. PubMed ID: 33022479
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  • 33. Structure-Based Design and Synthesis of N-Substituted 3-Amino-β-Carboline Derivatives as Potent αβ-Tubulin Degradation Agents.
    Li Y, Liu Y, Zhu Z, Yan W, Zhang C, Yang Z, Bai P, Tang M, Shi M, He W, Fu S, Liu J, Han K, Li J, Xie L, Ye H, Yang J, Chen L.
    J Med Chem; 2022 Feb 10; 65(3):2675-2693. PubMed ID: 35084853
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  • 34. SKLB060 Reversibly Binds to Colchicine Site of Tubulin and Possesses Efficacy in Multidrug-Resistant Cell Lines.
    Yan W, Yang T, Yang J, Wang T, Yu Y, Wang Y, Chen Q, Bai P, Li D, Ye H, Qiu Q, Zhou Y, Hu Y, Yang S, Wei Y, Li W, Chen L.
    Cell Physiol Biochem; 2018 Feb 10; 47(2):489-504. PubMed ID: 29794416
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  • 35. Synthesis and biological evaluation of new 2-methoxyestradiol derivatives: Potent inhibitors of angiogenesis and tubulin polymerization.
    Sun M, Zhang Y, Qin J, Ba M, Yao Y, Duan Y, Liu H, Yu D.
    Bioorg Chem; 2021 Aug 10; 113():104988. PubMed ID: 34034135
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  • 36. Cyclic bridged analogs of isoCA-4: Design, synthesis and biological evaluation.
    Pecnard S, Provot O, Levaique H, Bignon J, Askenatzis L, Saller F, Borgel D, Michallet S, Laisne MC, Lafanechère L, Alami M, Hamze A.
    Eur J Med Chem; 2021 Jan 01; 209():112873. PubMed ID: 33038796
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  • 37. Discovery of novel tubulin/HDAC dual-targeting inhibitors with strong antitumor and antiangiogenic potency.
    Wang Y, Sun M, Wang Y, Qin J, Zhang Y, Pang Y, Yao Y, Yang H, Duan Y.
    Eur J Med Chem; 2021 Dec 05; 225():113790. PubMed ID: 34454126
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  • 38. Design, synthesis, and biological evaluation of novel benzodiazepine derivatives as anticancer agents through inhibition of tubulin polymerization in vitro and in vivo.
    Pang Y, Lin H, Ou C, Cao Y, An B, Yan J, Li X.
    Eur J Med Chem; 2019 Nov 15; 182():111670. PubMed ID: 31499359
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  • 39. The discovery of novel indazole derivatives as tubulin colchicine site binding agents that displayed potent antitumor activity both in vitro and in vivo.
    Cui YJ, Ma CC, Zhang CM, Tang LQ, Liu ZP.
    Eur J Med Chem; 2020 Feb 01; 187():111968. PubMed ID: 31865012
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  • 40. Efficient Synthesis and Bioevaluation of Novel Dual Tubulin/Histone Deacetylase 3 Inhibitors as Potential Anticancer Agents.
    Peng X, Chen J, Li L, Sun Z, Liu J, Ren Y, Huang J, Chen J.
    J Med Chem; 2021 Jun 24; 64(12):8447-8473. PubMed ID: 34097389
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