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Journal Abstract Search

196 related items for PubMed ID: 32348628

  • 1. Design and Synthesis of Dihydroxamic Acids as HDAC6/8/10 Inhibitors.
    Morgen M, Steimbach RR, Géraldy M, Hellweg L, Sehr P, Ridinger J, Witt O, Oehme I, Herbst-Gervasoni CJ, Osko JD, Porter NJ, Christianson DW, Gunkel N, Miller AK.
    ChemMedChem; 2020 Jul 03; 15(13):1163-1174. PubMed ID: 32348628
    [Abstract] [Full Text] [Related]

  • 2. The structural requirements of histone deacetylase inhibitors: C4-modified SAHA analogs display dual HDAC6/HDAC8 selectivity.
    Negmeldin AT, Knoff JR, Pflum MKH.
    Eur J Med Chem; 2018 Jan 01; 143():1790-1806. PubMed ID: 29150330
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis, and biological activity of NCC149 derivatives as histone deacetylase 8-selective inhibitors.
    Suzuki T, Muto N, Bando M, Itoh Y, Masaki A, Ri M, Ota Y, Nakagawa H, Iida S, Shirahige K, Miyata N.
    ChemMedChem; 2014 Mar 01; 9(3):657-64. PubMed ID: 24403121
    [Abstract] [Full Text] [Related]

  • 4. Design, synthesis, and biological evaluation of indole-based hydroxamic acid derivatives as histone deacetylase inhibitors.
    Jiang BE, Hu J, Liu H, Liu Z, Wen Y, Liu M, Zhang HK, Pang X, Yu LF.
    Eur J Med Chem; 2022 Jan 05; 227():113893. PubMed ID: 34656899
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and Investigation of Therapeutic Potential of Isoform-Specific HDAC8 Inhibitors for the Treatment of Cutaneous T Cell Lymphoma.
    Umamaheswari A, Puratchikody A, Hari N.
    Anticancer Agents Med Chem; 2019 Jan 05; 19(7):916-934. PubMed ID: 30836926
    [Abstract] [Full Text] [Related]

  • 6. The HDAC6/8/10 inhibitor TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines.
    Kolbinger FR, Koeneke E, Ridinger J, Heimburg T, Müller M, Bayer T, Sippl W, Jung M, Gunkel N, Miller AK, Westermann F, Witt O, Oehme I.
    Arch Toxicol; 2018 Aug 05; 92(8):2649-2664. PubMed ID: 29947893
    [Abstract] [Full Text] [Related]

  • 7. Hydroxamic acid derivatives as HDAC1, HDAC6 and HDAC8 inhibitors with antiproliferative activity in cancer cell lines.
    Sixto-López Y, Gómez-Vidal JA, de Pedro N, Bello M, Rosales-Hernández MC, Correa-Basurto J.
    Sci Rep; 2020 Jun 26; 10(1):10462. PubMed ID: 32591593
    [Abstract] [Full Text] [Related]

  • 8. Design, Synthesis, and Pharmacological Evaluation of First-in-Class Multitarget N-Acylhydrazone Derivatives as Selective HDAC6/8 and PI3Kα Inhibitors.
    Rodrigues DA, Guerra FS, Sagrillo FS, de Sena M Pinheiro P, Alves MA, Thota S, Chaves LS, Sant'Anna CMR, Fernandes PD, Fraga CAM.
    ChemMedChem; 2020 Mar 18; 15(6):539-551. PubMed ID: 32022441
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis and biological evaluation of 3, 4-disubstituted-imidazolidine-2, 5-dione derivatives as HDAC6 selective inhibitors.
    Liang T, Xue J, Yao Z, Ye Y, Yang X, Hou X, Fang H.
    Eur J Med Chem; 2021 Oct 05; 221():113526. PubMed ID: 33992929
    [Abstract] [Full Text] [Related]

  • 10. Structure-based design generated novel hydroxamic acid based preferential HDAC6 lead inhibitor with on-target cytotoxic activity against primary choroid plexus carcinoma.
    Kassab SE, Mowafy S, Alserw AM, Seliem JA, El-Naggar SM, Omar NN, Awad MM.
    J Enzyme Inhib Med Chem; 2019 Dec 05; 34(1):1062-1077. PubMed ID: 31072216
    [Abstract] [Full Text] [Related]

  • 11. Discovery of the first histone deacetylase 6/8 dual inhibitors.
    Olson DE, Wagner FF, Kaya T, Gale JP, Aidoud N, Davoine EL, Lazzaro F, Weïwer M, Zhang YL, Holson EB.
    J Med Chem; 2013 Jun 13; 56(11):4816-20. PubMed ID: 23672185
    [Abstract] [Full Text] [Related]

  • 12. Discovery of meta-sulfamoyl N-hydroxybenzamides as HDAC8 selective inhibitors.
    Zhao C, Zang J, Ding Q, Inks ES, Xu W, Chou CJ, Zhang Y.
    Eur J Med Chem; 2018 Apr 25; 150():282-291. PubMed ID: 29533873
    [Abstract] [Full Text] [Related]

  • 13. The structural requirements of histone deacetylase inhibitors: SAHA analogs modified at the C5 position display dual HDAC6/8 selectivity.
    Negmeldin AT, Pflum MKH.
    Bioorg Med Chem Lett; 2017 Aug 01; 27(15):3254-3258. PubMed ID: 28648461
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and applications of benzohydroxamic acid-based histone deacetylase inhibitors.
    De Vreese R, D'hooghe M.
    Eur J Med Chem; 2017 Jul 28; 135():174-195. PubMed ID: 28453994
    [Abstract] [Full Text] [Related]

  • 15. Design and synthesis of novel and highly-active pan-histone deacetylase (pan-HDAC) inhibitors.
    Tashima T, Murata H, Kodama H.
    Bioorg Med Chem; 2014 Jul 15; 22(14):3720-31. PubMed ID: 24864038
    [Abstract] [Full Text] [Related]

  • 16. Design, synthesis and biological evaluation of tyrosine-based hydroxamic acid analogs as novel histone deacetylases (HDACs) inhibitors.
    Zhang Y, Feng J, Liu C, Fang H, Xu W.
    Bioorg Med Chem; 2011 Aug 01; 19(15):4437-44. PubMed ID: 21733698
    [Abstract] [Full Text] [Related]

  • 17. Replacement of the hydroxamic acid group in the selective HDAC8 inhibitor PCI-34051.
    Long K, Close DA, Johnston PA, Huryn DM.
    Bioorg Med Chem Lett; 2024 Aug 01; 108():129810. PubMed ID: 38782078
    [Abstract] [Full Text] [Related]

  • 18. Selective Inhibition of Histone Deacetylase 10: Hydrogen Bonding to the Gatekeeper Residue is Implicated.
    Géraldy M, Morgen M, Sehr P, Steimbach RR, Moi D, Ridinger J, Oehme I, Witt O, Malz M, Nogueira MS, Koch O, Gunkel N, Miller AK.
    J Med Chem; 2019 May 09; 62(9):4426-4443. PubMed ID: 30964290
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and Biological Investigation of Oxazole Hydroxamates as Highly Selective Histone Deacetylase 6 (HDAC6) Inhibitors.
    Senger J, Melesina J, Marek M, Romier C, Oehme I, Witt O, Sippl W, Jung M.
    J Med Chem; 2016 Feb 25; 59(4):1545-55. PubMed ID: 26653328
    [Abstract] [Full Text] [Related]

  • 20. Discovery of a series of hydroximic acid derivatives as potent histone deacetylase inhibitors.
    Zhang L, Wang X, Li X, Zhang L, Xu W.
    J Enzyme Inhib Med Chem; 2014 Aug 25; 29(4):582-9. PubMed ID: 24059701
    [Abstract] [Full Text] [Related]

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