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208 related items for PubMed ID: 32357547

  • 1. Upregulation of Sortilin, a Lysosomal Sorting Receptor, Corresponds with Reduced Bioavailability of Latent TGFβ in Mucolipidosis II Cells.
    Barnes JW, Aarnio-Peterson M, Norris J, Haskins M, Flanagan-Steet H, Steet R.
    Biomolecules; 2020 Apr 26; 10(5):. PubMed ID: 32357547
    [Abstract] [Full Text] [Related]

  • 2. The interactomics of sortilin: an ancient lysosomal receptor evolving new functions.
    Canuel M, Libin Y, Morales CR.
    Histol Histopathol; 2009 Apr 26; 24(4):481-92. PubMed ID: 19224451
    [Abstract] [Full Text] [Related]

  • 3. The inactivation of the sortilin gene leads to a partial disruption of prosaposin trafficking to the lysosomes.
    Zeng J, Racicott J, Morales CR.
    Exp Cell Res; 2009 Nov 01; 315(18):3112-24. PubMed ID: 19732768
    [Abstract] [Full Text] [Related]

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  • 5. Inappropriate cathepsin K secretion promotes its enzymatic activation driving heart and valve malformation.
    Lu PN, Moreland T, Christian CJ, Lund TC, Steet RA, Flanagan-Steet H.
    JCI Insight; 2020 Oct 15; 5(20):. PubMed ID: 33055423
    [Abstract] [Full Text] [Related]

  • 6. Analysis of mucolipidosis II/III GNPTAB missense mutations identifies domains of UDP-GlcNAc:lysosomal enzyme GlcNAc-1-phosphotransferase involved in catalytic function and lysosomal enzyme recognition.
    Qian Y, van Meel E, Flanagan-Steet H, Yox A, Steet R, Kornfeld S.
    J Biol Chem; 2015 Jan 30; 290(5):3045-56. PubMed ID: 25505245
    [Abstract] [Full Text] [Related]

  • 7. WNK4 enhances the degradation of NCC through a sortilin-mediated lysosomal pathway.
    Zhou B, Zhuang J, Gu D, Wang H, Cebotaru L, Guggino WB, Cai H.
    J Am Soc Nephrol; 2010 Jan 30; 21(1):82-92. PubMed ID: 19875813
    [Abstract] [Full Text] [Related]

  • 8. Sortilin mediates the lysosomal targeting of cathepsins D and H.
    Canuel M, Korkidakis A, Konnyu K, Morales CR.
    Biochem Biophys Res Commun; 2008 Aug 22; 373(2):292-7. PubMed ID: 18559255
    [Abstract] [Full Text] [Related]

  • 9. Cathepsin-Mediated Alterations in TGFß-Related Signaling Underlie Disrupted Cartilage and Bone Maturation Associated With Impaired Lysosomal Targeting.
    Flanagan-Steet H, Aarnio M, Kwan B, Guihard P, Petrey A, Haskins M, Blanchard F, Steet R.
    J Bone Miner Res; 2016 Mar 22; 31(3):535-48. PubMed ID: 26404503
    [Abstract] [Full Text] [Related]

  • 10. Sortilin associates with transforming growth factor-beta family proteins to enhance lysosome-mediated degradation.
    Kwon S, Christian JL.
    J Biol Chem; 2011 Jun 17; 286(24):21876-85. PubMed ID: 21521695
    [Abstract] [Full Text] [Related]

  • 11. The perlecan-interacting growth factor progranulin regulates ubiquitination, sorting, and lysosomal degradation of sortilin.
    Tanimoto R, Palladino C, Xu SQ, Buraschi S, Neill T, Gomella LG, Peiper SC, Belfiore A, Iozzo RV, Morrione A.
    Matrix Biol; 2017 Dec 17; 64():27-39. PubMed ID: 28433812
    [Abstract] [Full Text] [Related]

  • 12. UDP-GlcNAc-1-Phosphotransferase Is a Clinically Important Regulator of Human and Mouse Hair Pigmentation.
    Tiede S, Hundt JE, Paus R.
    J Invest Dermatol; 2021 Dec 17; 141(12):2957-2965.e5. PubMed ID: 34116066
    [Abstract] [Full Text] [Related]

  • 13. The lysosomal trafficking of acid sphingomyelinase is mediated by sortilin and mannose 6-phosphate receptor.
    Ni X, Morales CR.
    Traffic; 2006 Jul 17; 7(7):889-902. PubMed ID: 16787399
    [Abstract] [Full Text] [Related]

  • 14. Neuronal brain-derived neurotrophic factor is synthesized in excess, with levels regulated by sortilin-mediated trafficking and lysosomal degradation.
    Evans SF, Irmady K, Ostrow K, Kim T, Nykjaer A, Saftig P, Blobel C, Hempstead BL.
    J Biol Chem; 2011 Aug 26; 286(34):29556-67. PubMed ID: 21730062
    [Abstract] [Full Text] [Related]

  • 15. Lysosomal storage causes cellular dysfunction in mucolipidosis II skin fibroblasts.
    Otomo T, Higaki K, Nanba E, Ozono K, Sakai N.
    J Biol Chem; 2011 Oct 07; 286(40):35283-90. PubMed ID: 21846724
    [Abstract] [Full Text] [Related]

  • 16. Altered Met receptor phosphorylation and LRP1-mediated uptake in cells lacking carbohydrate-dependent lysosomal targeting.
    Aarnio-Peterson M, Zhao P, Yu SH, Christian C, Flanagan-Steet H, Wells L, Steet R.
    J Biol Chem; 2017 Sep 08; 292(36):15094-15104. PubMed ID: 28724630
    [Abstract] [Full Text] [Related]

  • 17. The novel Drosophila lysosomal enzyme receptor protein mediates lysosomal sorting in mammalian cells and binds mammalian and Drosophila GGA adaptors.
    Dennes A, Cromme C, Suresh K, Kumar NS, Eble JA, Hahnenkamp A, Pohlmann R.
    J Biol Chem; 2005 Apr 01; 280(13):12849-57. PubMed ID: 15664992
    [Abstract] [Full Text] [Related]

  • 18. Protein catabolism in fibroblasts cultured from patients with mucolipidosis II and other lysosomal disorders.
    Kopitz J, Arnold A, Meissner T, Cantz M.
    Biochem J; 1993 Oct 15; 295 ( Pt 2)(Pt 2):577-80. PubMed ID: 8240260
    [Abstract] [Full Text] [Related]

  • 19. Sortilin and prosaposin localize to detergent-resistant membrane microdomains.
    Canuel M, Bhattacharyya N, Balbis A, Yuan L, Morales CR.
    Exp Cell Res; 2009 Jan 15; 315(2):240-7. PubMed ID: 18992238
    [Abstract] [Full Text] [Related]

  • 20. Sortilin turnover is mediated by ubiquitination.
    Dumaresq-Doiron K, Jules F, Lefrancois S.
    Biochem Biophys Res Commun; 2013 Mar 29; 433(1):90-5. PubMed ID: 23485461
    [Abstract] [Full Text] [Related]

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